Results 61 to 70 of about 6,653 (163)

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini, E. Tartaglia, F. Cristofanelli, S. Gili, F. Maggi   +4 more
wiley   +1 more source

Systematic characterization of ubiquitination modification of EuFPS1 in Eucommia ulmoides

Industrial Crops and Products
The enzyme Farnesyl pyrophosphate Synthase (FPS) plays a critical role in the production process of Eucommia ulmoides rubber (Eu-rubber), catalyzing the production of farnesyl pyrophosphate (FPP), the direct precursor for rubber formation.
Yuhuan Jia, Qing Liang, Yi Zhang, Dan Zhao, Degang Zhao   +4 more
doaj   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Isolation and Characterization of Two Monoterpene Synthases and a Sesquiterpene Synthase from Asarum heterotropoides

Metabolites
Background: Asarum heterotropoides, a prominent medicinal plant in China, is well known for producing an abundance of monoterpenes and sesquiterpenes, which constitute the primary components of its essential oil and serve as the principal active ...
Jiayi Li, Qianhua Shen, Yongze Zhang, Hanshu Tao, Bingyi Xu, Xiaoyan Min, Haiyang Liu, Na Han, Xin Fang   +8 more
doaj   +1 more source

Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process

Journal of Diabetes Research, 2015
The proliferation of vascular smooth muscle cells (VSMCs) is one of the main features of atherosclerosis induced by high glucose. Mevalonate pathway is an important metabolic pathway that plays a key role in multiple cellular processes.
Guo-Ping Chen, Xiao-Qin Zhang, Tao Wu, Liang Li, Jie Han, Chang-Qing Du   +5 more
doaj   +1 more source

Expression of NAC6 Transcription Factor and Its Impact on Carotenoid Metabolism in Postharvest Mango Fruit [PDF]

Shipin Kexue
The NAC transcription factors play an important regulatory role in plant growth and development. In order to explore the impact of NAC6 on carotenoid metabolism in postharvest mango fruit, this study investigated changes in the carotenoid contents as ...
LIANG Minhua, LIANG Ruijin, YANG Zhenfeng, DENG Hongling
doaj   +1 more source

Aphid alarm pheromone (E)‐β‐farnesene: mechanisms, applications, and challenges in pest management

New Plant Protection, Volume 3, Issue 2, June 2026.
This review highlights the advances in the application of the aphid alarm pheromone (E)‐β‐farnesene (EβF) for pest management. It focuses on smart delivery systems, molecular optimization, synthetic biology, and integration with digital agriculture. Additionally, it discusses key challenges and future directions for enhancing stability, field efficacy,
Yi Yan, Yunhui Zhang, Xuguo Zhou, Xiangrui Li   +3 more
wiley   +1 more source

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto, Lucia Buccarello, Giuseppe Carota, Rocco Salvatore Calabrò, Carmela Rifici, Emanuela Esposito, Alessio Ardizzone, Giuseppe Caruso   +7 more
wiley   +1 more source

Targeting Brain Cholesterol Homeostasis in Alzheimer's Disease: Mechanisms and Therapeutic Perspectives

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan, Ameer Y. Taha, Walter Swardfager   +2 more
wiley   +1 more source

Production of borneol, camphor, and bornyl acetate using engineered Saccharomyces cerevisiae

Metabolic Engineering Communications
Microbial production of bicyclic monoterpenes is of great interest because their production primarily utilizes non-sustainable resources. Here, we report an engineered Saccharomyces cerevisiae yeast that produces bicyclic monoterpenes, including borneol,
Masahiro Tominaga, Kazuma Kawakami, Hiro Ogawa, Tomomi Nakamura, Akihiko Kondo, Jun Ishii   +5 more
doaj   +1 more source