Results 91 to 100 of about 5,164 (112)

Accumulation of nonesterified fatty acids in ischemic canine myocardium

American Journal of Physiology-Heart and Circulatory Physiology, 1984
In ischemic myocardium the time course of nonesterified fatty acid (NEFA) accumulation was studied in relation to changes in regional metabolism and mechanics. In open-chest dogs a coronary artery was partially occluded for 120 min. In the ischemic myocardium no increase was observed in NEFA content within 10 min, whereas changes were found in ...
Will A. Coumans, Robert S. Reneman, Frits W. Prinzen, Theo Arts, G. J. Van Der Vusse, Theo H.M. Roemen   +5 more
openaire   +3 more sources

Nonesterified fatty acids and endothelial dysfunction

International Congress Series, 2003
Nonesterified fatty acids (NEFA) induce vascular effects, such as the inhibition of insulin-induced nitric oxide (NO) production. In small arteries, relaxation is largely NO-independent. We aimed to assess the effect of elevated NEFA on NO-independent vasodilation. Protocols were performed before and after 120 min of a lipid emulsion infusion.
AVOGARO, ANGELO, DE KREUTZENBERG S, KIWANUKA E, TIENGO, ANTONIO   +3 more
openaire   +3 more sources

Mono‐ and polyenoic acid distribution in plasma nonesterified fatty acids in Kwashiorkor

Lipids, 1971
AbstractPlasma NEFA levels were determined in Kwashiorkor (17 cases) and normal infants (13 cases) by Dole's method. The distribution of mono‐ and polyenoic acids was investigated by Abdel‐Wahab's method. Plasma NEFA levels were found to be significantly lower in Kwashiorkor infants (445 μEq/L±32) than in normals (591 μEq/L±66).
F. Abdel-Wahab, K. Fayek, I. Fayad, A. A. Hafiez, K. Khalifa, L. Soliman   +5 more
openaire   +3 more sources

The effect of nonesterified fatty acids and progesterone on bupivacaine protein binding

Clinical Pharmacology and Therapeutics, 1986
We examined the influence of elevations in levels of nonesterified fatty acids (NEFAs) and progesterone concentrations on bupivacaine protein binding. The addition of NEFAs to isolated binding proteins of bupivacaine (alpha 1-acid glycoprotein and serum albumin) resulted in an increased binding to alpha 1-acid glycoprotein and an inconsistent decrease ...
Dennis E. Coyle, Divina J. Santos, Scott K. Essell, Donald D. Denson   +3 more
openaire   +3 more sources

Nonesterified fatty acids in blood pressure control and cardiovascular complications

Current Hypertension Reports, 2001
The fact that cardiovascular risk factors cluster among individuals with the insulin resistance syndrome strongly suggests a common pathogenetic denominator. For many years, abnormalities of nonesterified fatty acid metabolism have been implicated in the disturbances of carbohydrate and lipid metabolism that characterize the cluster.
Theodore L. Goodfriend, Eddie L. Greene, Brent M. Egan   +2 more
openaire   +2 more sources

Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells

American Journal of Physiology-Endocrinology and Metabolism, 1989
The effects of nonesterified fatty acids (NEFA) in modulating testosterone synthesis stimulated by luteinizing hormone (LH, 10 ng/sample) were investigated in isolated adult mouse Leydig cells. LH-stimulated testosterone production was inhibited by triglycerides (0-500 mg/dl, 50 mg/dl, 94% of the control and 500 mg/dl, 40%) and by a mixture of NEFA ...
W. D. Boam, John D. Stringham, A. W. Meikle, Xan-Hua Liu, S. J. Benson   +4 more
openaire   +3 more sources

Assay of Serum Nonesterified Fatty Acids by Atomic Absorption Spectrophotometry

American Journal of Clinical Pathology, 1973
Assay of nonesterified fatty acids in 100 μ l. of serum is described. The fatty acids are extracted with chloroform-heptane-methanol solvent, and their copper complexes are determined by atomic absorption spectrophotometry. This technic possesses the sensitivity (20 μ moles per 1.) and reliability (4.2% coefficient of variation) required for clinical ...
Derek P. Lehane, Mario Werner
openaire   +3 more sources

Nonesterified Fatty Acids and Development of Graft Failure in Renal Transplant Recipients

Transplantation, 2013
Chronic transplant dysfunction is the most common cause of graft failure on the long term. Proteinuria is one of the cardinal clinical signs of chronic transplant dysfunction. Albumin-bound fatty acids (FA) have been hypothesized to be instrumental in the etiology of renal damage induced by proteinuria.
Henri G. D. Leuvenink, Reinold O. B. Gans, H. Sijbrand Hofker, Astrid Klooster, Stephan J. L. Bakker, Gerjan Navis, Harry van Goor, Jaap J. Homan van der Heide   +7 more
openaire   +4 more sources

Effects of Nonesterified Fatty Acids on Glucose Metabolism After Glucose Ingestion

Diabetes, 1997
Impaired suppression of plasma nonesterified fatty acids (NEFAs) after glucose ingestion may contribute to glucose intolerance, but the mechanisms are unclear. Evidence that insulin inhibits hepatic glucose output (HGO), in part by suppressing plasma NEFA levels, suggests that impaired suppression of plasma NEFA after glucose ingestion would impair HGO
Joseph G. Yu, Debra Armstrong, Jerrold M. Olefsky, Mim I. Mulford, Yolanta T. Kruszynska   +4 more
openaire   +3 more sources

Nonesterified fatty acids in normal and diabetic rat sciatic nerve

Lipids, 1992
AbstractAlloxan‐induced diabetes in rats results in elevated levels of nonesterified fatty acids (NEFA) in whole sciatic nerve and its endoneurium. Increases in NEFA levels are more pronounced in whole diabetic nerve (40% over control) than in its endoneurial portion (20–30%).
Jyotiprakas Chattopadhyay, Harald H.O. Schmid, Ed W. Thompson   +2 more
openaire   +3 more sources