Results 41 to 50 of about 85,509 (245)

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

Advanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis, Joanne Heade, Cristiana Cunha, Marco van de Weert, Lasse Saaby, Stine Rønholt, Hanne Mørck Nielsen   +6 more
wiley   +1 more source

Synthesis of unsaturated fatty acids in the slime mold Physarum polycephalum and the zooflagellates Leishmania tarentolae, Trypanosoma lewisi, and Crithidia sp.: a comparative study

Journal of Lipid Research, 1965
On the basis of the unsaturated fatty acids which they synthesize, protists can be grouped in a meaningful way. Thus, the unsaturated fatty acids of the true slime mold are identical with the unsaturated fatty acids of the soil amoebae Acanthamoeba and ...
Edward D. Korn, Charles L. Greenblatt, Ann M. Lees   +2 more
doaj  

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Seasonal changes of fatty acids in Nerita textiles on intertidal area of Chabahar Bay (Oman Sea)

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2012
The aim of this research was to identify and isolate the fatty acids composition of Nerita textiles in intertidal area of Chabahar Bay, and also to explore the seasonal changes of fatty acid content in Nerita textiles.
N. Sajjadi email ; P. Eghtesadi; K. Darvish Bastami
doaj  

Recent Advances in Heterogeneous Frustrated Lewis Pair: Synthesis, Characterization, and Catalysis

Advanced Materials, EarlyView.
This review provides a concise analysis of heterogeneous frustrated Lewis pair (FLP) chemistry, focusing on their synthesis, characterization, and application in small‐molecule activation. It highlights current challenges in developing solid FLP systems and explores promising advancements through emerging technologies, offering critical insights into ...
Jiasi Li, Shik Chi Edman Tsang, Guangchao Li   +2 more
wiley   +1 more source

Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids

EBioMedicine, 2018
Depending on the length of their carbon backbone and their saturation status, natural fatty acids have rather distinct biological effects. Thus, longevity of model organisms is increased by extra supply of the most abundant natural cis-unsaturated fatty ...
Allan Sauvat, Guo Chen, Kevin Müller, Mingming Tong, Fanny Aprahamian, Sylvère Durand, Giulia Cerrato, Lucillia Bezu, Marion Leduc, Joakim Franz, Patrick Rockenfeller, Junichi Sadoshima, Frank Madeo, Oliver Kepp, Guido Kroemer   +14 more
doaj  

Chemoenzymatic Synthesis of ABC-Type Enantiostructured Triacylglycerols by the Use of the p-Methoxybenzyl Protective Group

Molecules
This report demonstrates the first asymmetric synthesis of enantiopure structured triacylglycerols (TAGs) of the ABC type presenting three non-identical fatty acids, two of which are unsaturated. The unsaturated fatty acids included monounsaturated oleic
Hafdis Haraldsdottir, Haraldur G. Gudmundsson, Kaisa M. Linderborg, Baoru Yang, Gudmundur G. Haraldsson   +4 more
doaj   +1 more source

INFLUENCE OF BREED AND SEASON ON THE FATTY ACID COMPOSITION OF GOAT MILK [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2023
It was analyzed how the content of fatty acids in the milk of Saanen goats and goats of Ukrainian breeding depended on the breed of goats. The experiment was based on a comparison of the content of fatty acids in the milk of 20 goats, of which 10 were ...
Oleksandr MYKHALKO, Victor OPARA, Iryna LEVCHENKO, Mykola PRIHODKO, Igor RUBTSOV, Tetiana CHERNIAVSKA   +5 more
doaj  

Bioinspired Design of Heterogenous Single‐Atomic‐Site Catalysts for Electrocatalysis and Photocatalysis

Advanced Materials, EarlyView.
This review gives a summary on the representative bioinspired single‐atomic‐site catalysts (SACs) and their applications in heterogeneous electrocatalysis and photocatalysis. The fundamentals of bioinspired design strategies are systematically discussed in the context of the first shell coordination, the second/long‐range coordination, and the outer ...
Ying Wang, Guangri Jia, Piaoping Yang, Linshan Zhang, Kwok‐Yin Wong   +4 more
wiley   +1 more source

Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C δ pathway

Journal of Lipid Research, 2007
Abnormal HDL metabolism among patients with diabetes and insulin resistance may contribute to their increased risk of atherosclerosis. ABCA1 mediates the transport of cholesterol and phospholipids from cells to HDL apolipoproteins and thus modulates HDL ...
Wang Yutong, John F. Oram
doaj