Results 41 to 50 of about 630,244 (294)

Redox-dependent anti-inflammatory signaling actions of unsaturated fatty acids.

Annual Review of Physiology, 2014
Unsaturated fatty acids are metabolized to reactive products that can act as pro- or anti-inflammatory signaling mediators. Electrophilic fatty acid species, including nitro- and oxo-containing fatty acids, display salutary anti-inflammatory and ...
Meghan M Delmastro-Greenwood, B. Freeman, S. Wendell   +2 more
semanticscholar   +1 more source

Long chain saturated and unsaturated fatty acids exert opposing effects on viability and function of GLP-1-producing cells: Mechanisms of lipotoxicity. [PDF]

PLoS ONE, 2017
BACKGROUND AND AIM:Fatty acids acutely stimulate GLP-1 secretion from L-cells in vivo. However, a high fat diet has been shown to reduce the density of L-cells in the mouse intestine and a positive correlation has been indicated between L-cell number and
Ketan Thombare, Stelia Ntika, Xuan Wang, Camilla Krizhanovskii   +3 more
doaj   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Membrane Fatty Acids and Physiological Disorders in Cold-Stored ‘Golden Delicious’ Apples Treated with 1-MCP and Calcium Chloride

Horticulturae, 2022
The present research intents to study skin fatty acids and physiological disorders developed during cold storage in ‘Golden Delicious’ apples treated with 1-MCP and calcium.
Maria Dulce Antunes, Ana Clara Guimarães, Custódia Gago, Adriana Guerreiro, Jorge Panagopoulos, Eduardo Vilas Boas, Maria Graça Miguel   +6 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Mixotrophic cultivation of Chlamydomonas for value added biomass production: Valorization of organic acid rich spent effluent

Current Research in Green and Sustainable Chemistry, 2021
This study explored on evaluation of Fatty Acid Methyl Ester (FAME) profile of Chlamydomonas sp. strain TERI-1 biomass, grown mixotrophically in organic acid rich Spent Effluent (SE).
Narasimhan Ramkumar, Debojyoti Mazumdar, Pallavi Mishra, Sanjukta Subudhi   +3 more
doaj  

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Tannin, protein contents and fatty acid compositions of the seeds of several Vicia L. species from Turkey

Grasas y Aceites, 2010
The seedoils of six Vicia species (Leguminosae) were investigated for their protein, tannin contents and fatty acid compositions. The protein contents of the seeds were found to be between 21.87%-31.33%.
Kağan Kökten, Alpaslan Koçak, Eyüp Bağci, Mevlüt Akçura, Sait Çelik   +4 more
doaj   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Saturated Fatty Acids, but Not Unsaturated Fatty Acids, Induce the Expression of Cyclooxygenase-2 Mediated through Toll-like Receptor 4*

Journal of Biological Chemistry, 2001
Results from our previous studies demonstrated that activation of Toll-like receptor 4 (Tlr4), the lipopolysaccharide (LPS) receptor, is sufficient to induce nuclear factor κB activation and expression of inducible cyclooxygenase (COX-2) in macrophages ...
J. Lee, K. Sohn, S. Rhee, D. Hwang
semanticscholar   +1 more source