Results 91 to 100 of about 3,880 (180)

Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis [PDF]

, 2014
Infantile hemangiomas (IHs) are non-malignant, largely cutaneous vascular tumors affecting approximately 5–10% of children to varying degrees. During the first year of life, these tumors are strongly proliferative, reaching an average size ranging from 2
AMAYA, CLARISSA, BISCHOFF, JOYCE, BOUCHERON, LAURA E., BRYAN, BRAD A., KOKTA, VICTOR, LACAZE, MARY, MITCHELL, DIANNE C., MULNE, ARLYNN, PHAM, ROBERT, ROWNTREE, REBECCA K., STILES, JESSICA   +10 more
core   +1 more source

Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats

Journal of Animal Breeding and Genetics, Volume 143, Issue 1, Page 152-171, January 2026.
ABSTRACT Detecting selection footprints offers valuable insight into evolutionary processes and the mechanisms underlying phenotypic diversity in selected traits. Domestication, natural and artificial selection, and breeding have produced indigenous goats well‐adapted to their local environments, making them crucial genetic resources. Understanding the
Sang Van Le, Panoraia Alexandri, Julius H.J. van der Werf, Luisa Olmo, Stephen W. Walkden‐Brown, Sara de Las Heras‐Saldana   +5 more
wiley   +1 more source

Distinct roles and molecular mechanisms of nicotine and benzo(a)pyrene in ferroptosis of lung adenocarcinoma and lung squamous cell carcinoma

Tobacco Induced Diseases
Introduction The essence of ferroptosis is the accumulation of membrane lipid peroxides caused by increased iron, which disrupts the redox balance within cells and triggers cell death.
Min G. Wen, Hui X. Zheng, Ying Z. Zhao, Pu Xia   +3 more
doaj   +1 more source

A transcriptomic approach for evaluating the relative potency and mechanism of action of azoles in the rat Whole Embryo Culture. [PDF]

, 2017
We evaluated the effect of six azoles on embryonic development in the rat whole embryo culture (WEC). Using the total morphological scoring system (TMS), we calculated the ID10concentration (effective dose for 10% decrease in TMS).
Dimopoulou, Myrto, Pennings, Jeroen L A, Piersma, Aldert H, Rietjens, Ivonne M C M, van Ravenzwaay, Bennard, Verhoef, Aart   +5 more
core   +3 more sources

Population-based genome-wide association study of plasma complex lipid species

Nature Communications
The human lipidome comprises numerous complex lipids, dysregulation of which can contribute to the pathogenesis of a wide range of diseases. Despite the high heritability of parts of the lipidome, the genetic architecture of many circulating lipid ...
Elvire N. Landstra, Mohammed A. Imtiaz, Valentina Talevi, Fabian Eichelmann, Matthias B. Schulze, N. Ahmad Aziz, Monique M. B. Breteler   +6 more
doaj   +1 more source

Cordyceps sinensis (CS) Alleviates Chronic Obstructive Pulmonary Disease Symptoms (COPD) by Targeting Inflammation, Apoptosis, and Oxidative Stress Through Ingredient–Gene–Disease Interaction

Immunity, Inflammation and Disease, Volume 13, Issue 12, December 2025.
Our findings indicate that Cordyceps Sinensis (CS) alleviates COPD symptoms by inhibiting inflammation and oxidative stress, with key biomarkers such as interleukins (ILs), tumor necrosis factor (TNF), and reactive oxygen species (ROS) identified. Activating autophagy serves as a protective mechanism against COPD development induced by oxidative stress.
Zirui Zang, Yuhan Kong, Qi Kong
wiley   +1 more source

Distinctive metabolic disturbances associated with redox homeostasis, nervous and hormonal functions during gut microbial enrichment upon polystyrene microplastic exposure

iMetaOmics, Volume 2, Issue 4, December 2025.
Microplastic‐induced gut microbial enrichment was dominated by bacteria within Eubacteriales, correlated with the virome, and accompanied by colitis. The polyamine synthetic pathway was activated to maintain glutathionylspermidine homeostasis, concurrent with decreases in pathways involved in the production of energy and reactive oxygen species under ...
Guozhu Ye, Zeming Wu, Guoyou Chen, Xuyi Liu, Yifang Duan, Minghui Li, Qiansheng Huang   +6 more
wiley   +1 more source

Additional file 1 of Raman spectroscopy biochemical characterisation of bladder cancer cisplatin resistance regulated by FDFT1: a review

, 2022
Additional file 1: Table S1. Raman peak assignments obtained from healthy bladder, low-grade bladder tumour and high-grade bladder tumour with symbols indicating, / : a peak with low intensity, // : a peak with greater intensity than / but lower than /// and /// : peak of high intensity.
Kanmalar, M., Abdul Sani, Siti Fairus, Kamri, Nur Izzahtul Nabilla B., Said, Nur Akmarina B. M., Jamil, Amirah Hajirah B. A., Kuppusamy, S., Mun, K. S., Bradley, D. A.   +7 more
openaire   +1 more source

A detailed genome-wide reconstruction of mouse metabolism based on human Recon 1 [PDF]

, 2010
Background Well-curated and validated network reconstructions are extremely valuable tools in systems biology. Detailed metabolic reconstructions of mammals have recently emerged, including human reconstructions.
Bernhard Ø Palsson, Eirikur Steingrimsson, Ines Thiele, Martin I Sigurdsson, Neema Jamshidi   +4 more
core   +2 more sources

Multiomics analyses reveal that PRMT5 regulates membrane transport and cholesterol synthesis in white adipocytes

iMetaOmics, Volume 2, Issue 4, December 2025.
Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen, Zhihao Jia, Xiashiyao Zhang, Feng Yue, James F. Markworth, Christina R. Ferreira, Jun Wan, Shihuan Kuang   +7 more
wiley   +1 more source