Results 61 to 70 of about 3,880 (180)

Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes

open access: yesBMC Medical Genetics, 2009
Background A genome-wide scan in unrelated US Caucasians identified rs7001819 upstream of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) and multiple variants within catenin (cadherin-associated protein), β-like 1 (CTNNBL1) to associate strongly with
Almind Katrine   +9 more
doaj   +1 more source

A case–control study in Taiwanese cohort and meta-analysis of serum ferritin in pancreatic cancer

open access: yesScientific Reports, 2021
Pancreatic cancer is one of the most lethal diseases which lack an early diagnostic marker. We investigated whether serum ferritin (SF) reflects risk for pancreatic cancer and potential genes that may contribute ferritin and pancreatic cancer risks.
Ji Min Park   +7 more
doaj   +1 more source

Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism [PDF]

open access: yes, 2008
Background Eukaryotic gene expression is a complex process involving multiple cis and trans activating molecules to either facilitate or inhibit transcription.
Sridar V Chittur   +2 more
core   +1 more source

Mapping molluscan endocrinology: a systematic and critical appraisal

open access: yesBiological Reviews, Volume 101, Issue 2, Page 970-1002, April 2026.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis   +3 more
wiley   +1 more source

Meta-analysis of SUMO1 [PDF]

open access: yes, 2008
An abundantly growing body of literature implicates conjugation of SUMO in the regulation of many proteins and processes, yet the regulation of SUMO pathways is poorly understood.
Brian J Wilson
core   +2 more sources

Unilateral mastication‐induced memory deficits linked to disrupted hippocampal cholesterol metabolism in rats

open access: yesVIEW, Volume 7, Issue 2, April 2026.
Unilateral mastication, a common oral habit, induces cognitive decline in rats by disrupting hippocampal cholesterol metabolism. It triggers astrocyte hyperplasia, enhances cholesterol synthesis, impairs transport/degradation, and reduces 24‐hydroxycholesterol (24‐OHC), ultimately damaging synaptic function.
Xiaoting Zhai   +9 more
wiley   +1 more source

Genome-wide search identified DNA methylation sites that regulate the metabolome

open access: yesFrontiers in Genetics, 2023
Background: Identifying DNA methylation sites that regulate the metabolome is important for several purposes. In this study, publicly available GWAS data were integrated to find methylation sites that impact metabolome through a discovery and replication
Majid Nikpay
doaj   +1 more source

Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the liver disease of our age? [PDF]

open access: yes, 2014
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to one-third of the adult population in industrialised countries.
Firneisz, Gábor
core   +1 more source

An Improved Genome Assembly of Azadirachta indica A. Juss.

open access: yesG3: Genes, Genomes, Genetics, 2016
Neem (Azadirachta indica A. Juss.), an evergreen tree of the Meliaceae family, is known for its medicinal, cosmetic, pesticidal and insecticidal properties.
Neeraja M. Krishnan   +4 more
doaj   +1 more source

Immune and Metabolic Biomarkers in a Rodent Model of Spinal Cord Contusion

open access: yesGlobal Spine Journal, 2022
Study Design: Basic science animal research study. Objectives: Using T10 spinal contused rats, we sought to identify molecular and circulating, metabolic and immune biomarkers during the subchronic and chronic recovery periods that may inform us ...
Christiano dos Santos e Santos MD   +6 more
doaj   +1 more source

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