Results 61 to 70 of about 3,880 (180)
Background A genome-wide scan in unrelated US Caucasians identified rs7001819 upstream of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) and multiple variants within catenin (cadherin-associated protein), β-like 1 (CTNNBL1) to associate strongly with
Almind Katrine +9 more
doaj +1 more source
A case–control study in Taiwanese cohort and meta-analysis of serum ferritin in pancreatic cancer
Pancreatic cancer is one of the most lethal diseases which lack an early diagnostic marker. We investigated whether serum ferritin (SF) reflects risk for pancreatic cancer and potential genes that may contribute ferritin and pancreatic cancer risks.
Ji Min Park +7 more
doaj +1 more source
Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism [PDF]
Background Eukaryotic gene expression is a complex process involving multiple cis and trans activating molecules to either facilitate or inhibit transcription.
Sridar V Chittur +2 more
core +1 more source
Mapping molluscan endocrinology: a systematic and critical appraisal
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis +3 more
wiley +1 more source
An abundantly growing body of literature implicates conjugation of SUMO in the regulation of many proteins and processes, yet the regulation of SUMO pathways is poorly understood.
Brian J Wilson
core +2 more sources
Unilateral mastication, a common oral habit, induces cognitive decline in rats by disrupting hippocampal cholesterol metabolism. It triggers astrocyte hyperplasia, enhances cholesterol synthesis, impairs transport/degradation, and reduces 24‐hydroxycholesterol (24‐OHC), ultimately damaging synaptic function.
Xiaoting Zhai +9 more
wiley +1 more source
Genome-wide search identified DNA methylation sites that regulate the metabolome
Background: Identifying DNA methylation sites that regulate the metabolome is important for several purposes. In this study, publicly available GWAS data were integrated to find methylation sites that impact metabolome through a discovery and replication
Majid Nikpay
doaj +1 more source
Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the liver disease of our age? [PDF]
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to one-third of the adult population in industrialised countries.
Firneisz, Gábor
core +1 more source
An Improved Genome Assembly of Azadirachta indica A. Juss.
Neem (Azadirachta indica A. Juss.), an evergreen tree of the Meliaceae family, is known for its medicinal, cosmetic, pesticidal and insecticidal properties.
Neeraja M. Krishnan +4 more
doaj +1 more source
Immune and Metabolic Biomarkers in a Rodent Model of Spinal Cord Contusion
Study Design: Basic science animal research study. Objectives: Using T10 spinal contused rats, we sought to identify molecular and circulating, metabolic and immune biomarkers during the subchronic and chronic recovery periods that may inform us ...
Christiano dos Santos e Santos MD +6 more
doaj +1 more source

