Results 171 to 180 of about 2,914 (186)

Punicalagin Targets FDX1 to Induce Cuproptosis for the Treatment of Gastric Cancer

IUBMB Life
ABSTRACT Gastric cancer represents the fifth most common malignancy globally and the third leading cause of cancer‐related deaths. Due to its insidious early symptoms and frequent metastasis at diagnosis, the survival rate remains dismal.
Yuan‐yuan Fang, Si‐yi Zhang, Chuan‐yu Leng, null Jing‐Lv, Shu‐fen Zhao, Xue‐ying Sun, null Xin‐Li, Yang‐yang Lu, null Bing‐Wang, Wei‐wei Qi   +9 more
openaire   +2 more sources

Genetic polymorphisms in TNFSF13 and FDX1 are associated with IgA nephropathy in the Han Chinese population

Human Immunology, 2015
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, and its pathogenesis is influenced by both genetic and environmental factors. In this study, we evaluated 23 tag single-nucleotide polymorphisms (tSNPs) in 21 IgAN-associated genes, in 200 subjects with IgAN and 310 healthy gender- and age-matched unrelated control subjects
Dan, Niu, Ya, Gao, Liyi, Xie, Jiping, Sun, Wanhong, Lu, Gang, Jin, Yaning, Hao, Yali, Zhang, Aiping, Yin, Yingzhou, Geng, Wenjing, Zhang, Cuiping, Chen, Shengbin, Li   +12 more
openaire   +2 more sources

Cuproptosis-Related Gene FDX1 Identified as a Potential Target for Human Ovarian Aging

Reproductive Sciences
Cuproptosis is a recently discovered mode of cell death that has garnered attention due to its association with various diseases. However, the intricate genetic relationship between cuproptosis and ovarian aging has remained largely unexplored.
Chia-Chun Wu, Chia-Jung Li, Li-Te Lin, Pei-Hsuan Lin, Zhi-Hong Wen, Jiin-Tsuey Cheng, Kuan-Hao Tsui   +6 more
openaire   +2 more sources

Mettl1 mitigates sepsis-induced cardiomyopathy via inhibition of FDX1-dependent cuproptosis

Gene
Sepsis-induced cardiomyopathy (SICM) significantly contributes to sepsis-related mortality, yet its molecular mechanisms remain incompletely understood. Here, we identify cuproptosis-a copper-dependent mitochondrial cell death pathway-as a critical driver of SICM pathogenesis.
Wei, Siang, Wang, Guoyun, Feng, Yan, Lin, Wenji   +3 more
openaire   +2 more sources

Assignment of ferredoxin 1 (FDX1) to bovine chromosome 15 with somatic cell hybrids.

Cytogenetics and cell genetics, 1998
1 tables 1 graph.
Elduque, C., Eggen, Andre, A.
openaire   +2 more sources

Anti-FDX1 Autoantibody as a Potential Biomarker for Non–Small Cell Lung Cancer Detection

Cancer Epidemiology, Biomarkers & Prevention
Abstract Background: Autoantibodies can be readily identified prior to biopsy and may serve as valuable biomarkers for cancer detection. Ferredoxin 1 (FDX1) is a key regulator in the process of cuproptosis and affects the prognosis of lung cancer. In this study, we investigated whether the anti-
Jing Li, Xiaobin Cao, Lulu Zhang, Aichen Liu, Siyu Liu, Fengqi Chen, Yutong Li, Hanke Ma, Wenke Sun, Songyun Ouyang, Liping Dai, Jingjing Liu   +11 more
openaire   +2 more sources

High FDX1 expression enhances the sensitivity of multiple myeloma cells to elesclomol

Blood
Abstract Background:Copper is an essential micronutrient required for regular physiological functions in the body. Dysregulated copper metabolism plays a crucial role in the progression of various types of cancer.
Hongyan Zhao, Fen He, Ruixin Gao, Maoyou Lu, Siqi Wang, Yu Chen, Wenya Pei, Xiuyun Tang, Jinyu Yan, Qianhao Li, Weihui Chen, Jiayu Liu, Lijun Peng, Jiliang Xia   +13 more
openaire   +1 more source

High expression of cuproptosis-related gene FDX1 in relation to good prognosis and immune cells infiltration in colon adenocarcinoma (COAD)

Journal of Cancer Research and Clinical Oncology, 2022
Jingyun Xu
exaly  

Cuproptosis-Related MiR-21-5p/FDX1 Axis in Clear Cell Renal Cell Carcinoma and Its Potential Impact on Tumor Microenvironment

Cells, 2023
Kun Han, Rongyang Dai, Ronghao Wang
exaly  

Functional genomics identifies a protective role for FDX1 in atherosclerosis

Nature Cardiovascular Research
Nicole Wayne, Marie A. Guerraty
openaire   +2 more sources