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Plasma anti-FDX1 autoantibody as a potential biomarker for detection and diagnosis of breast cancer

Clinical Immunology
Autoantibodies have emerged as highly valuable biomarkers for cancer detection. Ferredoxin 1 (FDX1), a key cuproptosis regulator, significantly influences breast cancer prognosis. This study aimed to investigate whether the anti-FDX1 autoantibody can serve as a novel biomarker for breast cancer detection and diagnosis. Anti-FDX1 levels were detected in
Fangfang, Liu   +3 more
openaire   +2 more sources

High FDX1 expression enhances the sensitivity of multiple myeloma cells to elesclomol

Blood
Abstract Background:Copper is an essential micronutrient required for regular physiological functions in the body. Dysregulated copper metabolism plays a crucial role in the progression of various types of cancer.
Hongyan Zhao   +13 more
openaire   +1 more source

Anti-FDX1 Autoantibody as a Potential Biomarker for Non–Small Cell Lung Cancer Detection

Cancer Epidemiology, Biomarkers & Prevention
Abstract Background: Autoantibodies can be readily identified prior to biopsy and may serve as valuable biomarkers for cancer detection. Ferredoxin 1 (FDX1) is a key regulator in the process of cuproptosis and affects the prognosis of lung cancer. In this study, we investigated whether the anti-
Jing Li   +11 more
openaire   +2 more sources

Targeting the cuproptosis regulator FDX1 for cancer therapy

Genome Instability & Disease
Luoling Wang, Weilin Chen
openaire   +1 more source

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