Results 81 to 90 of about 2,914 (186)
, 2023 Background: Kidney renal clear cell carcinoma (KIRC) is not sensitive to radiotherapy and chemotherapy, and only some KIRC patients can benefit from immunotherapy and targeted therapy.
Haixin Chen (4613332) +3 more
core +1 more source
, 2023 Background: Kidney renal clear cell carcinoma (KIRC) is not sensitive to radiotherapy and chemotherapy, and only some KIRC patients can benefit from immunotherapy and targeted therapy.
Haixin Chen (4613332) +3 more
core +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Exploration, EarlyView.The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng +10 more
wiley +1 more source
Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges
The Chemical Record, EarlyView.Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley +1 more source
Paired CycleGAN‐based virtual staining for 3D X‐ray histology of bone‐implant systems
Journal of Synchrotron Radiation, EarlyView.This work demonstrates virtual staining for 3D X‐ray histology using a modified CycleGAN trained on paired synchrotron radiation microtomography (SR‐µCT) and histology images of bone‐implant specimens. The method enables the generation of artificially coloured contrast resembling conventional histological staining from label‐free SR‐µCT data and is ...
Sarah C. Irvine +5 more
wiley +1 more source
Pharmacogenomics and Personalized Medicine, 2022 Cuproptosis is a novel copper-dependent cell death, and the copper level was increased in lung cancer patients. However, few studies evaluated the association between single-nucleotide polymorphisms (SNPs) in cuproptosis-related genes and lung cancer risk.Six SNPs of the SLC31A1, FDX1 and ATP7B genes were genotyped in a case-control cohort including ...
Yun Y, Wang Y, Yang E, Jing X
openaire +3 more sources
, 2010 Mammalian adrenodoxin (ferredoxin 1; Fdx1) is essential for the synthesis of various steroid hormones in adrenal glands. As a member of the [2Fe-2S] cluster-containing ferredoxin family, Fdx1 reduces mitochondrial cytochrome P450 enzymes, which then ...
Ulrich Mühlenhoff +9 more
core +1 more source
, 2023 Background: Kidney renal clear cell carcinoma (KIRC) is not sensitive to radiotherapy and chemotherapy, and only some KIRC patients can benefit from immunotherapy and targeted therapy.
Haixin Chen (4613332) +3 more
core +1 more source
, 2023 Background: Kidney renal clear cell carcinoma (KIRC) is not sensitive to radiotherapy and chemotherapy, and only some KIRC patients can benefit from immunotherapy and targeted therapy.
Haixin Chen (4613332) +3 more
core +1 more source