Results 41 to 50 of about 234,528 (304)

TIMING BEHAVIOR AND CONDITIONED FEAR [PDF]

Journal of the Experimental Analysis of Behavior, 1964
Rats were trained on a two‐response timing procedure which required that response B follow response A by at least a minimum specified interval in order to be reinforced with food. Repeated presentation (5 min on, 5 min off) of an auditory warning stimulus terminated by a brief electric shock to the feet (conditioned fear) produced a marked suppression ...
B, MIGLER, J V, BRADY
openaire   +2 more sources

Conditioned Fear Associated Phenotypes as Robust, Translational Indices of Trauma-, Stressor-, and Anxiety-related Behaviors

Frontiers in Psychiatry, 2014
Posttraumatic stress disorder (PTSD) is a heterogeneous disorder that affects individuals exposed to trauma (e.g., combat, interpersonal violence, and natural disasters).
Maria Anne Briscione, Tanja eJovanovic, Seth Davin Norrholm   +2 more
doaj   +1 more source

Trace Fear Conditioning in Mice [PDF]

Journal of Visualized Experiments, 2014
In this experiment we present a technique to measure learning and memory. In the trace fear conditioning protocol presented here there are five pairings between a neutral stimulus and an unconditioned stimulus. There is a 20 sec trace period that separates each conditioning trial.
Joaquin N, Lugo, Gregory D, Smith, Andrew J, Holley   +2 more
openaire   +2 more sources

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Measuring human trace fear conditioning

Psychophysiology, 2021
Abstract Trace fear conditioning is an important research paradigm to model aversive learning in biological or clinical scenarios, where predictors (conditioned stimuli, CS) and aversive outcomes (unconditioned stimuli, US) are separated in time.
Wehrli, Jelena M, Xia, Yanfang, Gerster, Samuel, Bach, Dominik R   +3 more
openaire   +5 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress

eLife, 2018
Glucocorticoid receptor (GR) is crucial for signaling mediated by stress-induced high levels of glucocorticoids. The lateral nucleus of the amygdala (LA) is a key structure underlying auditory-cued fear conditioning.
Ran Inoue, Kareem Abdou, Ayumi Hayashi-Tanaka, Shin-ichi Muramatsu, Kaori Mino, Kaoru Inokuchi, Hisashi Mori   +6 more
doaj   +1 more source

Fear expression is suppressed by tyrosine administration [PDF]

, 2019
Animal studies have demonstrated that catecholamines regulate several aspects of fear conditioning. In humans, however, pharmacological manipulations of the catecholaminergic system have been scarce, and their primary focus has been to interfering with ...
A Gerlicher, AD Abraham, BJ Jongkees, BS Glaeser, CA Hardman, CC Luck, CJ Merz, D Hermans, D Sevenster, DE Bush, DOL Teik, F Brischoux, FA Guarraci, FA Guarraci, FC Heath, GP McNally, HD Foster, HM Lachman, J Haaker, J Haaker, J Haaker, J Morriss, JD Fernstrom, JJ Li, JM Otis, JP Johansen, K Nader, K Raczka, KA de Souza Caetano, L Colzato, L Díaz-Mataix, LM Riby, LS Colzato, LY Atlas, M Kindt, M Matsumoto, M Nasehi, M Soeter, M Toth, MC Mithoefer, MC Mithoefer, MF Davies, N Whittle, O Dennison, O Holtzman-Assif, OA Onur, P Duits, P Waelti, R Cacciaglia, R Cools, R Marzagalli, RA Rescorla, RM Visser, RS Sutton, S Lissek, S Mathôt, S-Y Tam, SA Carmack, ST Mueller, T Agren, TB Lonsdorf, TB Lonsdorf, TD Zbozinek, TF Giustino, W Schultz, Y Ho, Z Brodnik   +66 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Short-Term Total Sleep-Deprivation Impairs Contextual Fear Memory, and Contextual Fear-Conditioning Reduces REM Sleep in Moderately Anxious Swiss Mice

Frontiers in Behavioral Neuroscience, 2017
The conditioning tasks have been widely used to model fear and anxiety and to study their association with sleep. Many reports suggest that sleep plays a vital role in the consolidation of fear memory.
Munazah F. Qureshi, Sushil K. Jha
doaj   +1 more source