Results 31 to 40 of about 12,053 (162)

Prognostic value of triglyceride-derived metabolic parameters for micro- and macrovascular complications and mortality in individuals with type 2 diabetes: The Rio de Janeiro type 2 diabetes cohort study. [PDF]

open access: yesDiabet Med
Prognostic value of triglyceride‐derived metabolic parameters for micro‐ and macrovascular complications and mortality in individuals with type 2 diabetes. Abstract Aims Triglyceride‐derived metabolic parameters have been proposed as indirect measures of insulin resistance and also as predictors of worse prognosis, mainly in Asian populations. However,
Cardoso CRL   +3 more
europepmc   +2 more sources

EFFICACY AND SAFETY OF SELADELPAR IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS PREVIOUSLY TREATED WITH FIBRATES OR OBETICHOLIC ACID

open access: yesAnnals of Hepatology
Introduction and Objectives: Seladelpar was evaluated as monotherapy or with ursodeoxycholic acid in RESPONSE (NCT04620733) among patients with primary biliary cholangitis.
Alejandra M. Villamil   +9 more
doaj   +1 more source

Lipid management in the prevention of stroke: a meta-analysis of fibrates for stroke prevention

open access: yesBMC Neurology, 2013
Background Fibrates has been extensively used to improve plasma lipid levels and prevent adverse cardiovascular outcomes. However, the effect of fibrates on stroke is unclear at the present time. We therefore carried out a comprehensive systematic review
Zhou Yu-Hao   +6 more
doaj   +1 more source

The Small Molecule PPARγ Agonist GL516 Induces Feeding-Stimulatory Effects in Hypothalamus Cells Hypo-E22 and Isolated Hypothalami

open access: yesMolecules, 2022
PPARγ agonists are implicated in the regulation of diabetes and metabolic syndrome and have therapeutic potential in brain disorders. PPARγ modulates appetite through its central effects, especially on the hypothalamic arcuate nucleus (ARC).
Annalisa Chiavaroli   +5 more
doaj   +1 more source

Statin and fibrate associed myopathy: study of eight patients [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2004
Lipid-lowering drugs have been occasionally associated with neuromuscular symptoms and muscle biopsy changes. We reported the clinical course and the muscle biopsy in eight patients with hyperlipoproteinemia, treated with lipid -lowering drugs (statins ...
Alzira A. Siqueira Carvalho   +2 more
doaj   +1 more source

Elucidating the Effects of the Lipids Regulators Fibrates and Statins on the Health Status of Finfish Species: A Review

open access: yesAnimals, 2023
The most documented fibrates are gemfibrozil, clofibrate and bezafibrate, while for statins, the majority of the published literature focuses on atorvastatin and simvastatin.
Manuel Blonç   +5 more
doaj   +1 more source

Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin

open access: yesLipids in Health and Disease, 2011
Background Fibrates have been reported to cause paradoxical decreases in HDL-C in certain patients. Design and methods This post-hoc analysis explored the frequency/magnitude of HDL-C reductions in a pooled database of mixed dyslipidemic patients (LDL-C ...
Farnier Michel   +4 more
doaj   +1 more source

Metabolic, Inflammatory and Imaging Biomarkers in Evaluation of Coronary Arteries Anatomical Stenosis in Patients with Stable Coronary Artery Disease

open access: yesРациональная фармакотерапия в кардиологии, 2020
Aim. To reveal the statistically significant determinants of the coronary artery (CA) stenosis ≥70% in patients with chronic stable CA disease receiving drug therapy.Material and methods.
O. A. Koshelskaya   +6 more
doaj   +1 more source

Ciprofibrate therapy in patients with hypertriglyceridemia and low high density lipoprotein (HDL)-cholesterol: greater reduction of non-HDL cholesterol in subjects with excess body weight (The CIPROAMLAT study)

open access: yesCardiovascular Diabetology, 2004
Background Hypertriglyceridemia in combination with low HDL cholesterol levels is a risk factor for cardiovascular disease. Our objective was to evaluate the efficacy of ciprofibrate for the treatment of this form of dyslipidemia and to identify factors ...
Medel Octavio   +25 more
doaj   +1 more source

The G\"odel Fibration

open access: yes, 2021
Comment: 39 ...
Trotta D., Spadetto M., Paiva V. D.
openaire   +4 more sources

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