Results 11 to 20 of about 14,279 (236)
Which is the best lipid-modifying strategy in metabolic syndrome and diabetes: fibrates, statins or both? [PDF]
Cardiovascular Diabetology, 2004 Although less clinical intervention studies have been performed with fibrates than with statins, there are evidences indicating that fibrates may reduce risk of cardiovascular events. The potential clinical benefit of the fenofibrate will be specified by
Tenenbaum Alexander, Fisman Enrique Z
doaj +2 more sources
BMC Research NotesFibrates can prevent and treat ischemic stroke (IS), the occurrence and development of IS is closely related to hypoxia-inducible factor-1A (HIF-1A). However, the exact mechanism by which fibrates regulate HIF-1A to treat IS remains unclear.
Fengjiao Yang +8 more
doaj +2 more sources
Lipid management in the prevention of stroke: a meta-analysis of fibrates for stroke prevention [PDF]
BMC Neurology, 2013 Background Fibrates has been extensively used to improve plasma lipid levels and prevent adverse cardiovascular outcomes. However, the effect of fibrates on stroke is unclear at the present time. We therefore carried out a comprehensive systematic review
Zhou Yu-Hao +6 more
doaj +3 more sources
Fibrates for the Treatment of Primary Biliary Cholangitis Unresponsive to Ursodeoxycholic Acid: An Exploratory Study [PDF]
Frontiers in Pharmacology, 2022 Aim: Up to 40% of patients with primary biliary cholangitis (PBC) will have a suboptimal biochemical response to ursodeoxycholic acid (UDCA), which can be improved by the addition of fibrates.
Guilherme Grossi Lopes Cançado +23 more
doaj +2 more sources
Milan Journal of Mathematics, 2022 AbstractWe review the theory of Lagrangian fibrations of hyperkähler manifolds as initiated by Matsushita. We also discuss more recent work of Shen–Yin and Harder–Li–Shen–Yin. Occasionally, we give alternative arguments and complement the discussion by additional observations.
D. Huybrechts, M. Mauri
openaire +4 more sources
Latent Fibrations: Fibrations for Categories of Partial Maps
Theory and Applications of Categories, 2021 65 pages, submitted to "Theory and Applications of Categories"
Cockett, Robin +3 more
openaire +3 more sources
Hepatology, EarlyView., 2022 Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan +22 more
wiley +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran +17 more
wiley +1 more source
Statins, fibrates and retinoic acid upregulate mitochondrial acylcarnitine carrier gene expression [PDF]
, 2009 In this study, we investigated the effects of statins, fibrates, 9-cis-retinoic acid and forskolin on the transcription of the mitochondrial carnitine/acylcarnitine carrier (CAC) gene.
Iacobazzi V +5 more
core +3 more sources