Results 41 to 50 of about 18,150,697 (227)

Decrease of fibrinolytic potential in the occurrence of cerebral ischemia [PDF]

Journal of Medical Biochemistry, 2008
One of the most present clinical manifestations of long and progressive atherothrombotic occurrences is the ischemic cerebrovascular insult, one of the leading causes of death and illness in the world.
Vučković Biljana, Đerić Mirjana, Ilić Tatjana, Čanak Višnja, Žarkov Marija   +4 more
doaj  

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Gene Targeting of Components of the Fibrinolytic System

, 2002
SummaryA number of in vitro and in vivo observations have implicated components of the fibrinolytic system in events associated with diverse physiological and pathophysiological processes, ranging from embryo implantation to cancer.
Francis Castellino, Victoria Ploplis
core   +1 more source

A STUDY ON THE CORRELATION BETWEEN THE CLINICAL COURSE OF EPIPHARYNGITIS AND THE ACTIVITY OF FIBRINOLYTIC SYSTEM [PDF]

, 1966
Although epipharyngitis shows few local symptoms, the inflammation is severe and connected with overall body symptoms. This is bionomical and pathological specificity of epipharyngitis. The pathology of epipharyngitis was investigated and the correlation
Shozo TANAKA, Sinsak HORIGUTI
core   +1 more source

Fibrinolytic Changes in Women with Preeclampsia

Clinical and Applied Thrombosis/Hemostasis, 2022
Objectives Preeclampsia (PE) is a serious complication of pregnancy. The fibrinolytic system play crucial roles regarding placentation and evolution of PE.
Anne Cathrine Godtfredsen MD, Johannes Jakobsen Sidelmann PhD, Britta Blume Dolleris MD, Jan Stener Jørgensen MD, PhD, Emma Kathrine Jungjohan Johansen, Melissa Fernard Bøg Pedersen, Yaseelan Palarasah PhD, Jørgen Brodersen Gram MD, D. Sc   +7 more
doaj   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Units of fibrinolytic system in mice with urokinase gene knockout in presence of growing B16/F10 melanoma

Южно-Российский онкологический журнал
Purpose of the study. Was to reveal the effect of urokinase gene knockout in male and female mice with transplanted  B16/F10 melanoma on the functions of the fibrinolytic system units.Materials and methods. Male and female mice were used: main group with
E. M. Frantsiyants, V. A. Bandovkina, E. I. Surikova, I. V. Kaplieva, Yu. A. Pogorelova, I. V. Neskubina, L. K. Trepitaki, N. D. Cheryarina, N. D. Ushakova, O. G. Ishonina, M. A. Gusareva, I. A. Udalenkova   +11 more
doaj   +1 more source

Evaluation of Anticoagulant Proteins and Fibrinolytic System Markers in Children with Pneumonia

Journal of Pediatric Research, 2019
Aim:Coagulation and fibrinolytic systems play an important role in the pathogenesis of complicated pneumonia. This study aims to evaluate and compare coagulation and fibrinolytic system markers and natural anticoagulant proteins with acute phase ...
Zahide Yalaki, Bülent Alioğlu, Nurdan Çiftçi, Fatma İnci Arıkan   +3 more
doaj   +1 more source