Results 21 to 30 of about 5,298,587 (157)

Repetitive Early 68Ga-FAPI PET Acquisition Comparing 68Ga-FAPI-02, 68Ga-FAPI-46, and 68Ga-FAPI-74: Methodologic and Diagnostic Implications for Malignant, Inflammatory/Reactive, and Degenerative Lesions. [PDF]

, 2022
68Ga-labeled fibroblast activation protein (FAP) inhibitor (68Ga-FAPI) PET targets 68Ga-FAPI-positive activated fibroblasts and is a promising imaging technique for various types of cancer and nonmalignant pathologies.
Liew, Dawn P, Huber, Peter E, Glatting, Frederik M, van Genabith, Antonia, Steinbach, Levin, Hubert, Alexander, Spektor, Anna-Maria, Kratochwil, Clemens, Kauczor, Hans-Ulrich, Haberkorn, Uwe, Dendl, Katharina, Giesel, Frederik L, Rathke, Hendrik, Hoppner, Jorge, Röhrich, Manuel, Levin Steinbach, Glatting, Frederik M., Dawn P. Liew, Jorge Hoppner, Manuel Röhrich, Peter E. Huber, Huber, Peter E., Liew, Dawn P., Clemens Kratochwil, Hans-Ulrich Kauczor, Hendrik Rathke, Alexander Hubert, Anna-Maria Spektor, Antonia van Genabith, Frederik M. Glatting, Katharina Dendl, Giesel, Frederik L., Uwe Haberkorn, Frederik L. Giesel   +33 more
core   +1 more source

DataSheet1_Mesoporous Polydopamine Loaded Pirfenidone Target to Fibroblast Activation Protein for Pulmonary Fibrosis Therapy.pdf

, 2022
Recently, fibroblast activation protein (FAP), an overexpressed transmembrane protein of activated fibroblast in pulmonary fibrosis, has been considered as the new target for diagnosing and treating pulmonary fibrosis.
Peng Hou (262071), Xinlu Wang (157696), Qun Luo (600767), Shaoyu Liu (3924080), Youcai Li (13152288), Ruiyue Zhao (6383009), Xiaoyao Zhang (13152291), Qi Fang (199280), Jiangyu Cui (10199588), Qian Han (133047), Jie Lv (235936)   +10 more
core   +1 more source

(68)Ga-FAPI-04 PET/CT Findings in Patients with Liver Cirrhosis

, 2023
Fibroblast activation protein (FAP) is expressed as a pro-inflammatory agent from fibrous tissue in liver cirrhosis and in the tumor microenvironment. Cirrhosis is the last stage of any chronic liver disease, and the natural course of cirrhosis is the ...
Beyhan, Ediz, Çermik, Tevfik Fikret, Tatar, Gamze, Fenercioglu, Ozge Erol, Sevindir, Isa, Sevindi, İsa, Erol Fenercioğlu, Özge, Ergül, Nurhan   +7 more
core   +1 more source

Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and FibrosisSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Fibroblast activation protein (FAP) is expressed on activated fibroblast. Its role in fibrosis and desmoplasia is controversial, and data on pharmacological FAP inhibition are lacking.
Ai-Ting Yang, Yong-Ook Kim, Xu-Zhen Yan, Hiroyuki Abe, Misbah Aslam, Kyoung-Sook Park, Xin-Yan Zhao, Ji-Dong Jia, Thomas Klein, Hong You, Detlef Schuppan   +10 more
doaj   +1 more source

Clinical and research applications of fibroblast activation protein-α inhibitor tracers: a review. [PDF]

Br J Radiol
Desaulniers M, Rousseau É, Pabst KM.
europepmc   +2 more sources

A Simple Kit Formulation for Preparation and Exploratory Human Studies of a Novel ^99mTc-Labeled Fibroblast Activation Protein Inhibitor Tracer for Imaging of the Fibroblast Activation Protein in Cancers

, 2023
Fibroblast activation protein (FAP) is a potential target for tumor diagnosis and treatment because it is selectively expressed on the cell membrane of cancer-associated fibroblasts in most solid tumor stroma. The aim of this study was to develop a 99mTc-
Cheng Zhou, Qianna Wang, Qing Ruan, Junhong Feng, Junbo Zhang, Junhong Feng (11835903), Jing Wang, Guoquan Li (1728292), Shu Zong (1728289), Fei Kang (476831), Yuhao Jiang (472152), Jing Wang (6206297), Shu Zong, Yuhao Jiang, Junbo Zhang (5715440), Guoquan Li, Cheng Zhou (307152), Qianna Wang (11835906), Qing Ruan (349572), Fei Kang   +19 more
core   +1 more source

Different Uptake of ⁶⁸Ga-FAPI and ¹⁸F-FDG in Lymphadenopathy Caused by Angioimmunoblastic T-Cell Lymphoma in a Patient with Colon Cancer

Diagnostics, 2022
An 82-year-old man with a history of colon cancer was found with multiple lymphadenopathies and a pulmonary mass. Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) detected generalized hypermetabolic lymph ...
Meiqi Wu, Qingqing Pan, Yaping Luo
doaj   +1 more source

False-Positive 68Ga-Fibroblast Activation Protein-Specific Inhibitor Uptake of Benign Lymphoid Tissue in a Patient With Breast Cancer

, 2021
Ga-68-fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT was performed in a patient with left lower outer quadrant breast cancer who had F-18-FDG PET/CT imaging.
Guzel, Yunus, Can, Canan, Alabalik, Ulas, Komek, Halil, Gundogan, Cihan   +4 more
core   +1 more source

Clinical applications of fibroblast activation protein‐targeted theranostics in oncologic and nononcologic disease: Current status and future directions

iRADIOLOGY, 2023
Quinoline‐based fibroblast activation protein (FAP) inhibitor (FAPI)‐based positron emission tomography (PET) imaging and radioligand therapy (RLT) are being investigated for use in a wide variety of diseases, and recent results have been promising. This
Hao Fu, Wei Guo, Jingxiong Huang, Hua Wu, Haojun Chen   +4 more
doaj   +1 more source

Visualization of fibroblast activation using (68)Ga-FAPI PET/CT after pulmonary vein isolation with pulsed field compared with cryoballoon ablation

, 2023
BACKGROUND: Pulsed-field ablation (PFA) is a novel ablation modality for atrial fibrillation (AF) ablating myocardium by electroporation without tissue-heating.
Christoph Rischpler, Tienush Rassaf, Rischpler, Christoph, Reza Wakili, Wakili, Reza, Ken Hermann, Kessler, Lukas, Lukas Kessler, Dobrev, Dobromir, Rassaf, Tienush, Johannes Siebermair, Dobromir Dobrev, Nekolla, Stephan G., Weber, Manuel M., Bruns, Florian, Bohnen, Jan-Eric, Lauenroth, Anna, Rattka, Manuel, Jana Kupusovic, Kupusovic, Jana, Stephan G. Nekolla, Siebermair, Johannes, Kupusovic, Jana;Kessler, Lukas;Bruns, Florian;Bohnen, Jan-Eric;Nekolla, Stephan G;Weber, Manuel M;Lauenroth, Anna;Rattka, Manuel;Hermann, Ken;Dobrev, Dobromir;Rassaf, Tienush;Wakili, Reza;Rischpler, Christoph;Siebermair, Johannes, Manuel Rattka, Hermann, Ken, Florian Bruns, Jan-Eric Bohnen, Kupusovic, Jana ; Kessler, Lukas ; Bruns, Florian ; Bohnen, Jan-Eric ; Nekolla, Stephan G. ; Weber, Manuel M. ; Lauenroth, Anna ; Rattka, Manuel ; Hermann, Ken ; Dobrev, Dobromir ; Rassaf, Tienush ; Wakili, Reza ; Rischpler, Christoph ; Siebermair, Johannes, Manuel M. Weber, Anna Lauenroth   +29 more
core   +1 more source