Results 71 to 80 of about 5,298,587 (157)

PET/CT and PET/MRI in Cancer Diagnosis and Management: A Comparative Clinical Perspective

iMetaMed, Volume 2, Issue 2, June 2026.
This review compares PET/CT and PET/MRI in cancer imaging, highlighting their complementary roles for precise diagnosis and staging. It evaluates their technical strengths, clinical performance across various cancers, and future directions, including AI and novel tracers.
Zijian Ding, Ran Xue, Qianxi Jin, Wangzheqi Zhang, Yali Wu, Baixuan Xu   +5 more
wiley   +1 more source

Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives

iRADIOLOGY, Volume 4, Issue 3, Page 206-218, June 2026.
This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo, Yuling Cui, Zhiye Fan, Chenxin Jiang, Bowen Fu, Guangbin Cui, Yanli He   +6 more
wiley   +1 more source

The Negative Impact of a Non‐Therapeutic Laparotomy in Patients With Inoperable Colorectal Peritoneal Metastases

Journal of Surgical Oncology, Volume 133, Issue 7, Page 843-851, June 2026.
ABSTRACT Background The peritoneum is the third most prevalent location for metastases of colorectal cancer. In patients with resectable disease, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS‐HIPEC) is the preferred treatment in the Netherlands, achieving median overall survival (OS) of 36–42 months. However, during
Teun van den Heuvel, Lars van Kesteren, Simon Nienhuijs, Pim Burger, Tineke Buffart, Jurriaan Tuynman, Ignace De Hingh   +6 more
wiley   +1 more source

The FAPI-FDG Mismatch: Unmasking an Occult Pancreatic Lesion via Fibroblast Activation Imaging Amidst Negative Glucose Metabolism and Morphological Findings [PDF]

Background: Fibroblast activation protein inhibitor (FAPI) positron emission tomography (PET) has emerged as a promising modality for imaging the tumor microenvironment, specifically targeting cancer-associated fibroblasts (CAFs).
Trias Nugrahadi, Arifudin Achmad, Hendra Budiawan, Nur Rohmat Maulana Saepudin, A Hussein S Kartamihardja   +4 more
core   +1 more source

Application of 18F‐FAPI PET/CT in Deep Infiltrating Endometriosis

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT This case report demonstrates the enhanced visualization capabilities of FAPI in visualizing deep infiltrating endometriosis (DIE) lesions compared to ultrasonography and MRI, suggesting its potential as a powerful diagnostic tool in the future.
Tongxin Chen, Ruyu Cai, Minge S. Li, Pingyue Yu, Xiangcheng Wang, Yifan Huang, Haili Li   +6 more
wiley   +1 more source

Next generation fibroblast activation protein (FAP) targeting PET tracers - The tetrazine ligation allows an easy and convenient way to 18F-labeled (4-quinolinoyl)glycyl-2-cyanopyrrolidines

, 2023
: Small-molecular fibroblast activation protein inhibitor (FAPI)-based tracer have been shown to be promising Positron Emission Tomography (PET) 68Ga-labeled radiopharmaceuticals to image a variety of tumors including pancreatic, breast, and colorectal ...
Moon, Euy-Sung, Battisti, Umberto Maria, R\uf6sch, Frank, De Loose, Joni, Herth, Matthias M., Van Rymenant, Yentl, De Meester, Ingrid, Poulie, Christian B.M., Shalgunov, Vladimir, Elvas, Filipe, Pieter Van Der Veken, Christian B.M. Poulie, Joni De Loose, Moon, Euy Sung, Van Der Veken, Pieter, Matthias M. Herth, Umberto Maria Battisti, Frank Rösch, Vladimir Shalgunov, Yentl Van Rymenant, Euy-Sung Moon, Ingrid De Meester, Filipe Elvas, Rösch, Frank   +23 more
core   +1 more source

Evaluation of myocardial fibrosis and wall motion abnormality with 68Ga-FAPI PET/MR in coronary heart disease

EJNMMI Research
Background To explore the characteristics of cardiac fibroblast activation protein inhibitor (FAPI) PET/MR in coronary heart disease (CHD) and its association with abnormal wall motion.
Rui Luo, Zhenyu Zhao, Chuan Zhang, Ru-Shuai Li, Yanrong Wang, Qingle Meng, Yudan Ni, Bolin Wang, Lanhua Li, Luan Feng, Rui Yang, Lin Xie, Xin Chen, Ming-Rong Zhang, Feng Wang   +14 more
doaj   +1 more source

Bioconjugation of a Fibroblast Activation Protein Targeted Interleukin‑4

Interleukin-4 (IL-4) is an immune-modulating therapeutic with growing potential for the treatment of inflammatory diseases. Current challenges of IL-4 therapy include a low serum half-life and pleiotropic activity, suggesting effective targeting of IL-4.
Olaf Prante (1626031), Tessa Lühmann (1532524), Matthias Ruopp (8585067), Simone Maschauer (1626028), Dorothee Haas (11888271), Lorenz Meinel (3509), Sha Zhu (312080), Rafael Worschech (17000685)   +7 more
core   +1 more source

Valvular and Myocardial Fibroblast Activation in Aortic Stenosis [PDF]

Activated fibroblasts drive leaflet thickening and left ventricular decompensation in aortic stenosis. Gallium-68 Fibroblast Activation Protein Inhibitor (68Ga-FAPI) binds to these key effector cells, and provides a readout of fibroblast activation.
van Beek, Edwin, Dey, Damini, McDermott, Michael, Williams, Michelle, Clark, Laura, Mahendran, Menaka, Whittington, Beth, Barton, Anna, Craig, Neil, Geers, Jolien, Loganath, Krithika, Balmforth, Craig, Lenell, Joel, Newby, David, Dweck, Marc, Slomka, Piotr, White, Audrey   +16 more
core   +1 more source

Applications of FAPI PET/CT in the diagnosis and treatment of breast and the most common gynecologic malignancies: a literature review

Frontiers in Oncology
The fibroblast activating protein (FAP) is expressed by some fibroblasts found in healthy tissues. However, FAP is overexpressed in more than 90% of epithelial tumors, including breast and gynecological tumors.
Tengfei Li, Tengfei Li, Tengfei Li, Jintao Zhang, Jintao Zhang, Jintao Zhang, Yuanzhuo Yan, Yuanzhuo Yan, Yuanzhuo Yan, Min Tan, Min Tan, Min Tan, Yue Chen, Yue Chen, Yue Chen   +14 more
doaj   +1 more source