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Fibroblast Growth Factors in Depression [PDF]
Frontiers in Pharmacology, 2019 Major depressive disorder (MDD) is one of the most serious diseases and now becomes a major public health problem in the world. The pathogenesis of depression remains poorly understood.
Zheng Deng +7 more
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Role of fibroblast growth factors in bone regeneration [PDF]
Inflammation and Regeneration, 2017 Bone is a metabolically active organ that undergoes continuous remodeling throughout life. However, many complex skeletal defects such as large traumatic bone defects or extensive bone loss after tumor resection may cause failure of bone healing ...
Pornkawee Charoenlarp +2 more
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New developments in the biology of fibroblast growth factors. [PDF]
WIREs Mech Dis, 2022 The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine kinases (FGFRs 1-4) and four intracellular proteins (intracellular FGFs or iFGFs)
Ornitz DM, Itoh N.
europepmc +2 more sources
Fibroblast growth factors [PDF]
Current Biology, 2003 What are they? Fibroblast growth factors (FGFs) are a family of small (20–30kDa) intercellular signalling proteins which are frequently found to be glycosylated. The first draft of the human genome identified 29 potential FGF genes, and so far transcripts have been identified for 23 of them.
I. Mason
semanticscholar +4 more sources
Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation [PDF]
Scientific Reports, 2023 Image-guided radiofrequency ablation (RFA) is used to treat focal tumors in the liver and other organs. Despite potential advantages over surgery, hepatic RFA can promote local and distant tumor growth by activating pro-tumorigenic growth factor and ...
Aurelia Markezana +14 more
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Endocrine Fibroblast Growth Factors in Relation to Stress Signaling [PDF]
Cells, 2022 Fibroblast growth factors (FGFs) play important roles in various growth signaling processes, including proliferation, development, and differentiation.
Makoto Shimizu, Ryuichiro Sato
doaj +2 more sources
Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration [PDF]
Journal of Tissue Engineering, 2010 Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation.
Ye-Rang Yun +8 more
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Fibroblast growth factors in the management of spinal cord injury. [PDF]
J Cell Mol Med, 2018 Spinal cord injury (SCI) possesses a significant health and economic burden worldwide. Traumatic SCI is a devastating condition that evolves through two successive stages.
Zhou Y, Wang Z, Li J, Li X, Xiao J.
europepmc +2 more sources
Recent Advances in the Role of Fibroblast Growth Factors in Hair Follicle Growth [PDF]
BiomoleculesHair follicles are essential to hair formation and cyclic regeneration, experiencing growth and degeneration, and quiescence phases involving complex signaling pathways.
Junchao Wang +3 more
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Roles of Fibroblast Growth Factors and Their Therapeutic Potential in Treatment of Ischemic Stroke [PDF]
Frontiers in Pharmacology, 2021 Stroke is the leading cause of death worldwide, and its treatment remains a challenge. Complex pathological processes are involved in stroke, which causes a reduction in the supply of oxygen and energy to the brain that triggers subsequent cascade events,
Confidence Dordoe +8 more
doaj +2 more sources