Results 1 to 10 of about 2,052,125 (407)

Fibroblast Growth Factors in Depression. [PDF]

Front Pharmacol, 2019
Major depressive disorder (MDD) is one of the most serious diseases and now becomes a major public health problem in the world. The pathogenesis of depression remains poorly understood. Fibroblast growth factors (FGFs) belong to a large family of growth factors that are involved in brain development during early periods as well as maintenance and ...
Deng Z, Deng S, Zhang MR, Tang MM.
europepmc   +7 more sources

Fibroblast growth factors as tissue repair and regeneration therapeutics. [PDF]

PeerJ, 2016
Cell communication is central to the integration of cell function required for the development and homeostasis of multicellular animals. Proteins are an important currency of cell communication, acting locally (auto-, juxta-, or paracrine) or ...
Nunes QM, Li Y, Sun C, Kinnunen TK, Fernig DG.   +4 more
europepmc   +6 more sources

Fibroblast growth factors [PDF]

Current Biology, 2003
What are they? Fibroblast growth factors (FGFs) are a family of small (20–30kDa) intercellular signalling proteins which are frequently found to be glycosylated. The first draft of the human genome identified 29 potential FGF genes, and so far transcripts have been identified for 23 of them.
I. Mason
openaire   +5 more sources

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. [PDF]

Cytokine & Growth Factor Reviews, 2005
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans ...
Aigner, Arany, Asplin, Auguste, Baird, Baird, Barleon, Bastaki, Bergonzoni, Bikfalvi, Birkle, Blotnick, Bornstein, Bossard, Bottazzi, Breviario, Brown, Brustle, Cao, Cao, Carmeliet, Carmeliet, Carmeliet, Castellon, Chadderton, Chang, Chang, Chang, Chi, Collo, Coltrini, Colvin, Comerota, Compagni, Conforti, Connolly, Costa, Cozzolino, Cross, Czubayko, Daviet, Davis, De Marchis, Dell’Era, Dell’Era, Dell’Era, Deng, Dennis, Desbaillets, Dirix, Eliceiri, Ensoli, Eriksson, Ferrara, Ferrara, Florkiewicz, Folkman, Folkman, Folkman, Freedman, Fulgham, Gabler, Gajdusek, Gajdusek, Garlanda, Gerritsen, Giavazzi, Giavazzi, Gillis, Giordano, Gleich, Gloe, Gonzalez, Griffioen, Grines, Gross, Gualandris, Gualandris, Hanahan, Hanneken, Hanneken, Hartnett, Henke, Herbert, Hiraoka, Ho, Hollingsworth, Hori, Hoying, Hsia, Iozzo, Itoh, Jaakkola, Javerzat, Jih, Kage, Kanda, Kanda, Kandel, Kaneko, Kasahara, Kazemi, Kitayama, Kiuru-Kuhlefelt, Klein, Konerding, Konkle, Koochekpour, Kumar, Kumar, Kumar, Kurz, Kuwabara, Laham, Landgren, Latini, Lazarous, Leali, Lederman, Lee, Lee, Li, Li, Lindahl, Liotta, Lopez, Lozano, Maciag, Magnusson, Mantovani, Margosio, Mathew, Matsumoto, Mattila, McCarthy, McCrohan, Mignatti, Mignatti, Miller, Mongiat, Montesano, Montesano, Morbidelli, Moscatelli, Nachman, Nguyen, Nico, Nicosia, Nurcombe, Ozaki, Padro, Parsons-Wingerter, Partridge, Passaniti, Pellegrini, Pendurthi, Peoples, Pepper, Pepper, Pepper, Perollet, Placanica, Polnaszek, Poole, Poon, Post, Presta, Presta, Presta, Presta, Presta, Presta, Pugh, Quarto, Rak, Reuss, Ria, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Rissanen, Rousseau, Ruegg, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Russo, Sahni, Sahni, Sahni, Sahni, Salgado, Salmivirta, Salustri, Schnaper, Schnaper, Seghezzi, Sellke, Senn, Sepp, Shaw, Sheibani, Shing, Shono, Shono, Simons, Simons, Singh, Souttou, Stokes, Syed, Tabata, Takahashi, Takei, Talarico, Tanghetti, Taraboletti, Taraboletti, Tassi, Taverna, Terranova, Tiefenbacher, Tille, Tobe, Tomanek, Ueno, Underwood, Unger, Vacca, Vlodavsky, Walford, Wang, Wang, Weidner, Weinstein, Wempe, Xu, Xue, Yamaguchi, Yamayoshi, Yoon, Zhang, Zhang, Zhao, Zhou, Zhou, Ziche, Ziche   +253 more
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Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells. [PDF]

, 2015
Epithelial-to-mesenchymal transition (EMT) plays a critical role in cancer metastasis, and is regulated by growth factors such as transforming growth factor β (TGF-β) and fibroblast growth factors (FGF) secreted from the stromal and tumor cells. However,
Hamada, Yoshinosuke, Ito, Ayano, Kawaguchi, Naomasa, Kodaira, Moe, Matsuura, Nariaki, Mori, Seiji, Okazaki, Mika, Takada, Yoshikazu   +7 more
core   +17 more sources

Conversion of a Paracrine Fibroblast Growth Factor into an Endocrine Fibroblast Growth Factor [PDF]

Journal of Biological Chemistry, 2012
FGFs 19, 21, and 23 are hormones that regulate in a Klotho co-receptor-dependent fashion major metabolic processes such as glucose and lipid metabolism (FGF21) and phosphate and vitamin D homeostasis (FGF23). The role of heparan sulfate glycosaminoglycan in the formation of the cell surface signaling complex of endocrine FGFs has remained unclear. Here
Goetz R, Ohnishi M, Kir S, Kurosu H, Wang L, Pastor J, Ma J, Gai W, Kuro-o M, Razzaque MS, Mohammadi M   +10 more
openaire   +2 more sources

Role of Fibroblast Growth Factor Receptor 2 in Pancreatic Cancer: Potential Target for New Therapeutic Approach? [PDF]

, 2015
Fibroblast growth factors and their receptors play a key role in cell proliferation, migration and differentiation. Fibroblast growth factor receptor 2 (FGFR2) is involved in carcinogenesis and its altered expression has been shown in several tumors ...
Angeloni, Antonio, Ceccarelli, Simona, Vescarelli, Enrica   +2 more
core   +1 more source

Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes [PDF]

, 2020
Fibroblast growth factors (FGFs) are key regulators of tissue development, homeostasis and repair, and abnormal FGF signalling is associated with various human diseases.
Ben-Yehuda Greenwald, Maya, Chen, Lin, Iizuka, Haruka, Jukic, Marko, Kubo, Fumimasa, Meyer, Michael, Ornitz, David M, Rauschendorfer, Theresa, Sänger, Catharina, Werner, Sabine   +9 more
core   +2 more sources

Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]

, 2017
An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto, Ferroni, Letizia, Gardin, Chiara, Mijiritsky, Eitan, Piattelli, Adriano, Zanette, Gastone, Zavan, Barbara   +6 more
core   +2 more sources

Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]

, 2017
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo, Altissimi, Giancarlo, Artico, Marco, Bardella, Lia, Giangaspero, Felice, Minni, Antonio, Parnigotto, Pier Paolo, Pastore, Francesco Saverio, Spoletini, Marialuisa, Taurone, Samanta, Tombolini, Mario, Wierzbicki, Venceslao   +11 more
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