Fibroblast Growth Factors in Depression [PDF]
Frontiers in Pharmacology, 2019 Major depressive disorder (MDD) is one of the most serious diseases and now becomes a major public health problem in the world. The pathogenesis of depression remains poorly understood.
Zheng Deng +7 more
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Fibroblast growth factors as tissue repair and regeneration therapeutics [PDF]
PeerJ, 2016 Cell communication is central to the integration of cell function required for the development and homeostasis of multicellular animals. Proteins are an important currency of cell communication, acting locally (auto-, juxta-, or paracrine) or ...
Quentin M. Nunes +4 more
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Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation [PDF]
Scientific Reports, 2023 Image-guided radiofrequency ablation (RFA) is used to treat focal tumors in the liver and other organs. Despite potential advantages over surgery, hepatic RFA can promote local and distant tumor growth by activating pro-tumorigenic growth factor and ...
Aurelia Markezana +14 more
doaj +2 more sources
Endocrine Fibroblast Growth Factors in Relation to Stress Signaling [PDF]
Cells, 2022 Fibroblast growth factors (FGFs) play important roles in various growth signaling processes, including proliferation, development, and differentiation.
Makoto Shimizu, Ryuichiro Sato
doaj +2 more sources
Roles of Fibroblast Growth Factors and Their Therapeutic Potential in Treatment of Ischemic Stroke [PDF]
Frontiers in Pharmacology, 2021 Stroke is the leading cause of death worldwide, and its treatment remains a challenge. Complex pathological processes are involved in stroke, which causes a reduction in the supply of oxygen and energy to the brain that triggers subsequent cascade events,
Confidence Dordoe +8 more
doaj +2 more sources
Role of fibroblast growth factors in bone regeneration [PDF]
Inflammation and Regeneration, 2017 Bone is a metabolically active organ that undergoes continuous remodeling throughout life. However, many complex skeletal defects such as large traumatic bone defects or extensive bone loss after tumor resection may cause failure of bone healing ...
Pornkawee Charoenlarp +2 more
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System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. [PDF]
PLoS Genetics, 2013 Many fibroblast-secreted proteins promote tumorigenicity, and several factors secreted by cancer cells have in turn been proposed to induce these proteins.
Megha Rajaram +3 more
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Fibroblast Growth Factors in the Management of Acute Kidney Injury Following Ischemia-Reperfusion [PDF]
Frontiers in Pharmacology, 2020 Ischemia-reperfusion injury (IRI), which is triggered by a transient reduction or cessation of blood flow followed by reperfusion, is a significant cause of acute kidney injury (AKI).
Lian-Cheng Deng +5 more
doaj +2 more sources
Antagonism of interferon signaling by fibroblast growth factors promotes viral replication [PDF]
EMBO Molecular Medicine, 2020 Fibroblast growth factors (FGFs) play key roles in the pathogenesis of different human diseases, but the cross‐talk between FGFs and other cytokines remains largely unexplored.
Luigi Maddaluno +17 more
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Functional Diversity of Fibroblast Growth Factors in Bone Formation [PDF]
International Journal of Endocrinology, 2015 The functional significance of fibroblast growth factor (FGF) signaling in bone formation has been demonstrated through genetic loss-of-function and gain-of-function approaches.
Yuichiro Takei +2 more
doaj +2 more sources