Role of fibroblast growth factors in bone regeneration. [PDF]
Inflamm Regen, 2017 Bone is a metabolically active organ that undergoes continuous remodeling throughout life. However, many complex skeletal defects such as large traumatic bone defects or extensive bone loss after tumor resection may cause failure of bone healing ...
Charoenlarp P, Rajendran AK, Iseki S.
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Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration [PDF]
Journal of Tissue Engineering, 2010 Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation.
Ye-Rang Yun +8 more
doaj +2 more sources
Fibroblast Growth Factors in Schizophrenia [PDF]
Schizophrenia Bulletin, 2009 A large association study by O'Donovan et al recently suggested that genetic variation in fibroblast growth factor receptor (FGFR) 2 increases the risk for developing schizophrenia. Fibroblast growth factors (FGFs) are part of the family of glial growth factors; they control the growth and patterning of specific brain structures and regulate the ...
Steven C. Bakker +2 more
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System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity [PDF]
PLoS Genetics, 2013 Many fibroblast-secreted proteins promote tumorigenicity, and several factors secreted by cancer cells have in turn been proposed to induce these proteins.
Egeblad, M. +3 more
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Model of the early development of thalamo-cortical connections and area patterning via signaling molecules [PDF]
Journal of Computational Neuroscience 17: 347-363 (2004), 2004 The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors.
Ermentrout, G. B., Karbowski, Jan
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Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation. [PDF]
Sci Rep, 2023 Image-guided radiofrequency ablation (RFA) is used to treat focal tumors in the liver and other organs. Despite potential advantages over surgery, hepatic RFA can promote local and distant tumor growth by activating pro-tumorigenic growth factor and ...
Markezana A +14 more
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Endocrine Fibroblast Growth Factors in Relation to Stress Signaling. [PDF]
Cells, 2022 Fibroblast growth factors (FGFs) play important roles in various growth signaling processes, including proliferation, development, and differentiation.
Shimizu M, Sato R.
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Roles of Fibroblast Growth Factors and Their Therapeutic Potential in Treatment of Ischemic Stroke. [PDF]
Front Pharmacol, 2021 Stroke is the leading cause of death worldwide, and its treatment remains a challenge. Complex pathological processes are involved in stroke, which causes a reduction in the supply of oxygen and energy to the brain that triggers subsequent cascade events,
Dordoe C +6 more
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The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors. [PDF]
Molecular and Cellular Biology, 1988 Xiaobei Zhan +3 more
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Fibroblast growth factors in the management of spinal cord injury. [PDF]
J Cell Mol Med, 2018 Spinal cord injury (SCI) possesses a significant health and economic burden worldwide. Traumatic SCI is a devastating condition that evolves through two successive stages.
Zhou Y, Wang Z, Li J, Li X, Xiao J.
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