New developments in the biology of fibroblast growth factors. [PDF]
WIREs Mech Dis, 2022 The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine kinases (FGFRs 1-4) and four intracellular proteins (intracellular FGFs or iFGFs)
Ornitz DM, Itoh N.
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Sulfated polysaccharides interact with fibroblast growth factors and protect from denaturation [PDF]
FEBS Open Bio, 2019 Fibroblast growth factors (FGFs) regulate embryonic development and homeostasis, including tissue and organ repair and specific aspects of metabolism.
Changye Sun +6 more
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Fibroblast Growth Factors in Schizophrenia [PDF]
Schizophrenia Bulletin, 2009 A large association study by O'Donovan et al recently suggested that genetic variation in fibroblast growth factor receptor (FGFR) 2 increases the risk for developing schizophrenia. Fibroblast growth factors (FGFs) are part of the family of glial growth factors; they control the growth and patterning of specific brain structures and regulate the ...
Afke F, Terwisscha van Scheltinga +2 more
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Agent based modelling helps in understanding the rules by which fibroblasts support keratinocyte colony formation [PDF]
, 2008 Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and bovine serum for clinical use. With growing concerns about the safety of these xenobiotic materials, it is desirable to culture keratinocytes in media ...
A Macieira-Coelho +90 more
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Role of FGF-18 in Bone Regeneration
Journal of Functional Biomaterials, 2023 In tissue engineering, three key components are cells, biological/mechanical cues, and scaffolds. Biological cues are normally proteins such as growth factors and their derivatives, bioactive molecules, and the regulators of a gene.
Kavipriya Murugaiyan +3 more
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The Regenerative Potential of bFGF in Dental Pulp Repair and Regeneration
Frontiers in Pharmacology, 2021 Regenerative endodontic therapy intends to induce the host’s natural wound-healing process, which can restore the vitality, immunity, and sensitivity of the inflammatory or necrotic pulp tissue destroyed by infection or trauma.
Keyue Liu, Sijing Yu, Ling Ye, Bo Gao
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Comparative genomic analysis of eutherian fibroblast growth factor genes
BMC Genomics, 2020 Background The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either ...
Marko Premzl
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Serum intact fibroblast growth factor 23 in healthy paediatric population
Open Medicine, 2021 It is believed that fibroblast growth factor 23 (FGF23) can become an early biomarker of chronic kidney disease progression. Data on FGF23 age dependency are inconsistent.
Stanczyk Malgorzata +3 more
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The Efficacy of Fibroblast Growth Factor for the Treatment of Chronic Vocal Fold Scarring: From Animal Model to Clinical Application [PDF]
Clinical and Experimental Otorhinolaryngology, 2017 Objectives This study assessed the regenerative efficacy of basic fibroblast growth factor (FGF) in a rabbit model of chronic vocal fold scarring and then confirmed its utility and safety in a prospective trial of patients with this condition.
Myung Jin Ban +6 more
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Fibroblast growth factors in the management of spinal cord injury. [PDF]
J Cell Mol Med, 2018 Spinal cord injury (SCI) possesses a significant health and economic burden worldwide. Traumatic SCI is a devastating condition that evolves through two successive stages.
Zhou Y, Wang Z, Li J, Li X, Xiao J.
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