Results 91 to 100 of about 7,998 (276)

Antibiotics Increase Gut Metabolism and Antioxidant Proteins and Decrease Acute Phase Response and Necrotizing Enterocolitis in Preterm Neonates [PDF]

, 2012
Background: The appropriate use of antibiotics for preterm infants, which are highly susceptible to develop necrotizing enterocolitis (NEC), is not clear.
Cilieborg, MS, Jensen, ML, Jiang, P, Sangild, PT, Sit, WH, Thymann, T, Tipoe, GL, Wan, JMF   +7 more
core   +1 more source

Analysis of the distribution of ficolin gene polymorphisms (FCN2) in children with bronchial asthmas of various severity

Medical Immunology
Asthma is one of the most common chronic diseases in all age groups. Asthma has heterogeneous phenotypes with different etiologies. Many parameters are used to classify asthma, for example, the severity and level of flow control.
M. Smolnikova, K. Afonicheva, I. Marchenko, S. Tereshchenko   +3 more
semanticscholar   +1 more source

H-ficolin (ficolin-3) concentrations and FCN3 gene polymorphism in neonates

Immunobiology, 2012
Serum H-ficolin (ficolin-3) concentrations (n=613) and FCN3 genotypes (n=529) from a large group of neonates are presented. Both pre-term deliveries and low birthweight (independently of gestational age) were significantly associated with low H-ficolin concentrations but not with heterozygosity for the FCN3 1637delC frameshift mutation. The presence of
Agnieszka Szala, Anna St. Swierzko, David C. Kilpatrick, Anna Sokolowska, Iwona Domzalska-Popadiuk, Jolanta Lukasiewicz, Czeslaw Lugowski, Czeslaw Lugowski, Mateusz Michalski, Jerzy Szczapa, Maciej Cedzynski, Anna Maciejewska, Monika Borkowska-Klos, Misao Matsushita   +13 more
openaire   +3 more sources

Association of Ficolin-2 Serum Levels and FCN2 Genetic Variants with Indian Visceral Leishmaniasis. [PDF]

PLoS ONE, 2015
Visceral leishmaniasis (VL), one of the neglected tropical diseases, is endemic in the Indian subcontinent. Ficolins are circulating serum proteins of the lectin complement system and involved in innate immunity.We have estimated ficolin-2 serum levels ...
Anshuman Mishra, Justin S Antony, Pandarisamy Sundaravadivel, Hoang Van Tong, Christian G Meyer, Reshma D Jalli, Thirumalaisamy P Velavan, Kumarasamy Thangaraj   +7 more
doaj   +1 more source

Quantitative Proteomic Analysis of Cardiac Xenograft Failure in a Pig‐to‐Non‐Human Primate Model Identifies NF‐κB as a Critical Immunomodulatory Target

Xenotransplantation, Volume 32, Issue 3, May/June 2025.
ABSTRACT Introduction Shortage of donor organs is one of the greatest challenges of cardiac transplantation. Xenotransplantation is a potential way to solve the contradiction of imbalance and pigs are considered ideal donor sources. However, xenotransplantation still faces the problem of immune rejection at present.
Hao Cui, Zirui Liu, Songren Shu, Xin Yan, Xiumeng Hua, Yuan Chang, Xiao Chen, Menghao Tao, Mingming Su, Mengxia Fu, Shengshou Hu, Jiangping Song   +11 more
wiley   +1 more source

Serum MASP-1 in complex with MBL activates endothelial cells. [PDF]

, 2014
The complement system plays an important role in the induction of inflammation. In this study we demonstrate that the initiation complexes of the lectin pathway, consisting of mannose-binding lectin (MBL) and associated serine proteases (MASPs) elicit ...
Ambrus, Balázs Major, Beinrohr, Dahl, Davis, Degn, Degn, Degn, Degn, Dobó, Dobó, Dobó, Endre Schwaner, Erika Kajdácsi, Gulla, Gál, Hansen, Heja, Heja, Hess, Jensenius, János Rigó, József Dobó, Kidmose, Kocsis, László Cervenak, Matsushita, Matsushita, Matsushita, Megyeri, Megyeri, Márton Megyeri, Møller-Kristensen, Oroszlán, Paréj, Paréj, Péter Gál, Péter K. Jani, Péter Závodszky, Ricklin, Saeed, Skjoedt, Steffen Thiel, Stover, Takahashi, Thiel, Thiel, Thiel, Thiel, Thiel, van der Pol   +50 more
core   +1 more source

Repetitive transcranial magnetic stimulation elicits weight loss and improved insulin sensitivity in type 2 diabetic rats

Animal Models and Experimental Medicine, Volume 8, Issue 4, Page 739-749, April 2025.
Repetitive transcranial magnetic stimulation (rTMS) can significant improve insulin sensitivity in rats with type 2 diabetes, accompanied by weight loss. The beneficial effects of rTMS are partly attributable to a central‐to‐peripheral regulatory action of rTMS on hepatic lipid metabolism, a novel finding which is worth further exploration.
Xuanjin Chen, Ruru Wang, Xin Wang, Ming Liu, Zhipeng Liu, Tao Yin, Chen Li   +6 more
wiley   +1 more source

Using Interleukin 6 and 8 in Blood and Bronchoalveolar Lavage Fluid to Predict Survival in Hematological Malignancy Patients With Suspected Pulmonary Mold Infection. [PDF]

, 2019
Background: Molds and other pathogens induce elevated levels of several cytokines, including interleukin (IL)-6 and IL-8. The objective of this study was to investigate the prognostic value of IL-6 and IL-8 as well as fungal biomarkers in blood and ...
Eigl, Susanne, Flick, Holger, Heldt, Sven, Hoenigl, Martin, Jenks, Jeffrey D, Krause, Robert, Neumeister, Peter, Prattes, Juergen, Prüller, Florian, Rabensteiner, Jasmin, Rawlings, Stephen A, Strohmaier, Heimo, Wölfler, Albert   +12 more
core   +1 more source

The Role of Cholesterol Metabolism and Its Regulation in Tumor Development

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Background Within the tumor microenvironment, tumor cells undergo metabolic reprogramming of cholesterol due to intrinsic cellular alterations and changes in the extracellular milieu. Furthermore, cholesterol reprogramming within this microenvironment influences the immune landscape of tumors, facilitating immune evasion and consequently ...
Yongmei Wu, Wenqian Song, Min Su, Jing He, Rong Hu, Youbo Zhao   +5 more
wiley   +1 more source

Differential Role of the Lectin Pathway of Complement Activation in Susceptibility to Neonatal Sepsis [PDF]

, 2017
Background. The incidence of bacterial sepsis during the neonatal period is high. Mannan-binding lectin (MBL), L-ficolin, and H-ficolin recognize microorganisms and activate the complement system viaMBL-associated serine proteases (MASPs).
Boillat, Colette, Christoph, Aebi, Jensenius, Jens C., Mattmann, Maika, Nelle, Mathias, Otth, Margrith, Schlapbach, Luregn J., Thiel, Steffen, Wagner, Bendicht   +8 more
core