Results 71 to 80 of about 4,930 (172)
Research progress on biomarkers of traumatic brain injury
Animal Models and Experimental Medicine, Volume 9, Issue 6, Page 1065-1104, June 2026.Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source
Respiratory Research, 2019 Background The incidence of infectious disease caused by nontuberculous mycobacteria is increasing worldwide. Pulmonary Mycobacterium avium complex (MAC) disease is difficult to treat with chemotherapy, and its mechanism of infection, infection route ...
Tomofumi Kobayashi +10 more
doaj +1 more source
Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 126-138, June 2026.High‐resolution single‐cell atlas of normal gastric tissue, primary gastric cancer, and metastatic lesions. (A) Schematic diagram of experimental design. (B) Bar plot for qualified cell numbers in each lesion. (C) Cells annotation by canon markers for all cells. (D) Bubble chart for canon marker genes for each cell subtype.
Min Sun +3 more
wiley +1 more source
The Role of Ficolins in Innate Immunity
Immunobiology, 2002 Ficolins are a group of proteins containing both a collagen-like domain and a fibrinogen-like domain and are found in varying tissues. Ficolins present in sera have a lectin activity toward N-acetylglucosamine through their fibrinogen-like domains. The domain organizations between ficolins and mannose-binding lectin (MBL) are very similar in that both ...
Misao, Matsushita, Teizo, Fujita
openaire +2 more sources
Association of L-ficolin levels and FCN2 genotypes with chronic Chagas disease.
PLoS ONE, 2013 BackgroundL-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the complement system.MethodsWe investigated L-ficolin levels in 160 T.
Paola R Luz +5 more
doaj +1 more source
Clinical and Translational Science, Volume 19, Issue 5, May 2026.ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein +8 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao +3 more
wiley +1 more source
Iranian Journal of Parasitology, 2013 Background: Malaria remains a serious public health problem with significant morbidity and mortal-ity. This study was conducted to identify whether ficolin-A could play an active role of against mala-ria infection.
F Chen +7 more
doaj +2 more sources
Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo
Scientific Reports, 2017 Ficolins are a family of pattern recognition molecules that are capable of activating the lectin pathway of complement. A limited number of reports have demonstrated a protective role of ficolins in animal models of infection.
Ninette Genster +5 more
doaj +1 more source