Results 71 to 80 of about 7,922 (214)
M-ficolin in children with cancer
Immunobiology, 2011 M-ficolin (ficolin-1) is a complement-activating pattern-recognition molecule structurally related to mannan-binding lectin. It is produced by monocytes and neutrophils, and is found in serum. Its biological role is largely unknown. We assessed M-ficolin concentration in serum from pediatric cancer patients.
Schlapbach, Luregn J. +6 more
openaire +4 more sources
Mouse mannose-binding lectin-A and ficolin-A inhibit lipopolysaccharide-mediated pro-inflammatory responses on mast cells [PDF]
BMB Reports, 2013 It is unknown how soluble pattern-recognition receptors inblood, such as mannose-binding lectin (MBL) and ficolins,modulate mast cell-mediated inflammatory responses. Weinvestigate how mouse MBL-A or ficolin-A regulate mouse bonemarrow-derived mast cells
Ying Jie Ma +5 more
doaj +1 more source
GALDIERO is CO-FIRST AUTHOR. Phagocytes as Corrupted Policemen in Cancer-Related Inflammation [PDF]
, 2015 Inflammation is a key component of the tumor microenvironment. Tumor-associated macrophages (TAMs) and tumor-associated neutrophils (TANs) are prototypic inflammatory cells in cancer-related inflammation.
Bonavita, Eduardo +3 more
core +1 more source
The Disulfide Bonding Pattern in Ficolin Multimers [PDF]
Journal of Biological Chemistry, 2004 Ficolin is a plasma lectin, consisting of a short N-terminal multimerization domain, a middle collagen domain, and a C-terminal fibrinogen-like domain. The collagen domains assemble the subunits into trimers, and the N-terminal domain assembles four trimers into 12-mers.
Tomoo, Ohashi, Harold P, Erickson
openaire +2 more sources
PLoS ONE, 2012 BackgroundThe innate immune system encompasses various recognition molecules able to sense both exogenous and endogenous danger signals arising from pathogens or damaged host cells.
Christian Gytz Ammitzbøll +7 more
doaj +1 more source
Frontiers in Immunology, 2018 Enteroaggregative Escherichia coli (EAEC) causes acute and persistent diarrhea worldwide. Still, the involvement of host factors in EAEC infections is unresolved. Binding of recognition molecules from the lectin pathway of complement to EAEC strains have
Camilla Adler Sørensen +5 more
doaj +1 more source
Yersinia enterocolitica O:3 Outer Membrane Vesicles as a Platform for Complement Activation
Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.Basic characteristics and biological activity of outer membrane vesicles (OMVs) secreted by Yersinia enterocolitica O:3 (YeO3), depending on LPS chemotype and growth temperature. ABSTRACT Lipopolysaccharide (LPS) is the major component of the outer membrane vesicles (OMVs) of Gram‐negative bacteria.
Cédric Battaglino +15 more
wiley +1 more source
Scientific Reports, 2021 H-ficolin recognizes patterns on microorganisms and stressed cells and can activate the lectin pathway of the complement system. We aimed to assess H-ficolin in relation to the progression of diabetic kidney disease (DKD), all-cause mortality, diabetes ...
Jakob Appel Østergaard +9 more
doaj +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.Proteomic profiling of tissue explant‐ and plasma‐derived extracellular vesicles identified colon adenocarcinoma‐associated and healthy‐associated EV proteins. A 10‐protein EV panel enabled highly sensitive blood‐based detection of colon adenocarcinoma, showed marked postoperative changes, and retained performance in an independent validation cohort ...
Yura Seo +33 more
wiley +1 more source
Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin [PDF]
, 2009 Udgivelsesdato: 2009-Sep-15Chitin is a highly acetylated compound and the second most abundant biopolymer in the world next to cellulose. Vertebrates are exposed to chitin both through food ingestion and when infected with parasites, and fungi and chitin
Holmskov, Uffe +7 more
core +1 more source