Results 81 to 90 of about 2,459 (190)

The 3D Dynamics of a Wildfire Plume Extending Across the Top of the Planetary Boundary Layer Using an Airborne Doppler Lidar

Geophysical Research Letters, Volume 52, Issue 11, 16 June 2025.
Abstract As wildfire pervasiveness increases with a changing climate, there is a need to develop new techniques with emerging technologies to understand the interaction between wildfires and the surrounding atmosphere at a high spatiotemporal resolution.
E. J. Strobach, S. Baidar, B. J. Carroll, W. A. Brewer   +3 more
wiley   +1 more source

Aryl hydrocarbon receptor (AHR) is a novel druggable pathway controlling malignant progenitor proliferation in chronic myeloid leukemia (CML).

PLoS ONE, 2018
Aryl Hydrocarbon Receptor (AHR) is an ubiquitous basic helix-loop-helix transcription factor, which is ligand-activated and involved in numerous biological processes including cell division, cell quiescence and inflammation. It has been shown that AHR is
Melanie Gentil, Patricia Hugues, Christophe Desterke, Gladys Telliam, Ivan Sloma, Lucas E B Souza, Seda Baykal, Jerome Artus, Frank Griscelli, Agnes Guerci, Hyacinthe Johnson-Ansah, Adlen Foudi, Annelise Bennaceur-Griscelli, Ali G Turhan   +13 more
doaj   +1 more source

Multifaceted Role of Microbiota‐Derived Indole‐3‐Acetic Acid in Human Diseases and Its Potential Clinical Application

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
The complexity of indole‐3‐acetic acid's (IAA's) role in human health and disease. IAA is a multifaceted compound with significant consequences for several physiological and pathological processes. ABSTRACT Indole‐3‐acetic acid (IAA) is recognized as a common plant growth hormone.
Nargis Shaheen, Jiaxing Miao, Boyu Xia, Yutong Zhao, Jing Zhao   +4 more
wiley   +1 more source

Epigenetically Mediated Pathogenic Effects of Phenanthrene on Regulatory T Cells

Journal of Toxicology, 2013
Phenanthrene (Phe), a polycyclic aromatic hydrocarbon (PAH), is a major constituent of urban air pollution. There have been conflicting results regarding the role of other AhR ligands 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and 6-formylindolo [3,2-b ...
Jing Liu, Luhua Zhang, Lisa C. Winterroth, Marco Garcia, Shannon Weiman, Jillian W. Wong, John B. Sunwoo, Kari C. Nadeau   +7 more
doaj   +1 more source

Photo-oxidation products of skin surface squalene mediate metabolic and inflammatory responses to solar UV in human keratinocytes.

PLoS ONE, 2012
UnlabelledThe study aimed to identify endogenous lipid mediators of metabolic and inflammatory responses of human keratinocytes to solar UV irradiation.
Vladimir Kostyuk, Alla Potapovich, Andrea Stancato, Chiara De Luca, Daniela Lulli, Saveria Pastore, Liudmila Korkina   +6 more
doaj   +1 more source

Effects of UV and FICZ on the EGFR signalling in NHEK.

, 2012
A. Western blot detection of the phosphorylated forms of EGFR (P-EGFR) and ERK (P-ERK) in total lysates of untreated NHEK (-) and post-UV irradiation; B.
Daniela Lulli (139088), Chiara De Luca (139084), Liudmila Korkina (122497), Andrea Stancato (139081), Alla Potapovich (139075), Saveria Pastore (139092), Vladimir Kostyuk (139070)   +6 more
core   +1 more source

Additional file 3 of Aryl hydrocarbon receptor signals attenuate lung fibrosis in the bleomycin-induced mouse model for pulmonary fibrosis through increase of regulatory T cells

, 2020
Additional file 3: Figure S3. FICZ did not affect the number of CD4+Foxp3+ Tregs in the spleen. BLM at 0.06 units/animal was intratracheally administered with (denoted as FICZ) or without FICZ (vehicle).
Hiroshi Takei (38173), Tsutomu Takeuchi (163145), Keiko Yoshimoto (839655), Hidekata Yasuoka (522923)   +3 more
core   +1 more source

Evaluation of the role of AHR agonist FICZ in the growth of leukemic CD34+ cells.

, 2018
CML CD34+ cells were cultured in the presence of indicated concentrations of FICZ and the cell numbers at day7 were compared to day 0. The use of FICZ induced a decrease of the growth of CD34+ cells at day+7 with the most inhibitory effects observed at ...
Patricia Hugues (5616785), Gladys Telliam (5616788), Jerome Artus (5616800), Ali G. Turhan (155505), Annelise Bennaceur-Griscelli (155516), Lucas E. B. Souza (5616794), Hyacinthe Johnson-Ansah (5616806), Adlen Foudi (5616809), Seda Baykal (5616797), Christophe Desterke (760909), Ivan Sloma (5616791), Melanie Gentil (5616782), Frank Griscelli (171241), Agnes Guerci (5616803)   +13 more
core   +1 more source

Mechanistic Role of the Ah Receptor (AHR) Ligand 6-Formyllindolo[3,2-b]Carbazole (FICZ) in Cytochrome P450 (CYP)1a Induction by Hyperoxia, and Protection of Lung Injury by FICZ [PDF]

A51. PEDIATRIC CRITICAL CARE INCLUDING INTERVENTIONAL BRONCHOSCOPY, 2020
B. Moorthy, K. Lingappan, X. Couroucli
openaire   +1 more source

Quercetin, Resveratrol, and Curcumin Are Indirect Activators of the Aryl Hydrocarbon Receptor (AHR)

, 2016
Several polyphenols have been shown to activate the aryl hydrocarbon receptor (AHR) in spite of the fact that they bind to the receptor with low affinity.
Ulf Rannug (1375752), Afshin Mohammadi-Bardbori (1456156), Johanna Bengtsson (2043952), Emma Wincent (1375749), Agneta Rannug (1375758)   +4 more
core   +1 more source