Results 1 to 10 of about 10,264 (194)

DegP Initiates Regulated Processing of Filamentous Hemagglutinin in Bordetella bronchiseptica [PDF]

mBio, 2021
Two-partner secretion (TPS) systems are broadly distributed among Gram-negative bacteria and play important roles in bacterial pathogenesis. FhaB-FhaC is the prototypical member of the TPS family and we here identified the protease that initiates a ...
Richard M. Johnson, Zachary M. Nash, Margaret R. Dedloff, John C. Shook, Peggy A. Cotter   +4 more
doaj   +7 more sources

Pertactin-Negative and Filamentous Hemagglutinin-Negative Bordetella pertussis, Australia, 2013–2017 [PDF]

Emerging Infectious Diseases, 2019
During the 2008–2012 pertussis epidemic in Australia, pertactin (Prn)–negative Bordetella pertussis emerged. We analyzed 78 isolates from the 2013–2017 epidemic and documented continued expansion of Prn-negative ptxP3 B. pertussis strains.
Zheng Xu, Sophie Octavia, Laurence Don Wai Luu, Michael Payne, Verlaine Timms, Chin Yen Tay, Anthony D. Keil, Vitali Sintchenko, Nicole Guiso, Ruiting Lan   +9 more
doaj   +6 more sources

Pseudomonas fluorescens filamentous hemagglutinin, an iron-regulated protein, is an important virulence factor that modulates bacterial pathogenicity [PDF]

Frontiers in Microbiology, 2016
Pseudomonas fluorescens is a common bacterial pathogen to a wide range of aquaculture animals including various species of fish. In this study, we employed proteomic analysis and identified filamentous hemagglutinin (FHA) as an iron-responsive protein ...
Yuan-yuan Sun, Yuan-yuan Sun, Yuan-yuan Sun, Heng Chi, Heng Chi, Li Sun, Li Sun   +6 more
doaj   +4 more sources

Cooperative Roles for Fimbria and Filamentous Hemagglutinin in Bordetella Adherence and Immune Modulation [PDF]

mBio, 2015
Bordetella fimbriae (FIM) are generally considered to function as adhesins despite a lack of experimental evidence supporting this conclusion for Bordetella pertussis and evidence against a requirement for FIM in adherence of Bordetella bronchiseptica to
Erich V. Scheller, Jeffrey A. Melvin, Amanda J. Sheets, Peggy A. Cotter   +3 more
doaj   +5 more sources

The use of filamentous hemagglutinin adhesin to detect immune responses to Campylobacter hepaticus infections in layer hens [PDF]

Frontiers in Veterinary Science, 2022
Campylobacter hepaticus is the aetiological agent of Spotty Liver Disease (SLD). SLD can cause significant production loss and mortalities among layer hens at and around peak of lay.
Chithralekha Muralidharan, José A. Quinteros, Arif Anwar, Timothy B. Wilson, Peter C. Scott, Robert J. Moore, Thi Thu Hao Van   +6 more
doaj   +2 more sources

Subcutaneous administration of a fusion protein composed of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis induces mucosal and systemic immune responses [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): After decades of containment, pertussis disease, caused by Bordetella pertussis seems to be re-emerging and still remains a major cause of reported vaccine-preventable deaths worldwide.
Ali Torkashvand, Fariborz Bahrami, Minoo Adib, Soheila Ajdary   +3 more
doaj   +2 more sources

Pasteurella multocida filamentous hemagglutinin B1 (fhaB1) gene is not involved with avian fowl cholera pathogenesis in turkey poults [PDF]

BMC Veterinary Research
Background Pasteurella multocida is a Gram-negative coccobacillus and is the causative agent of fowl cholera in avian species. P. multocida expresses two large filamentous hemagglutinin (FhaB) proteins encoded by fhaB1 and fhaB2 genes. Previously, it was
Rohana P. Dassanayake, Robert E. Briggs, Bryan S. Kaplan, Harish Menghwar, Carly Kanipe, Eduardo Casas, Fred M. Tatum   +6 more
doaj   +2 more sources

Bordetella filamentous hemagglutinin and adenylate cyclase toxin interactions on the bacterial surface are consistent with FhaB-mediated delivery of ACT to phagocytic cells [PDF]

mBio
Bordetella species that cause respiratory infections in mammals include B. pertussis, which causes human whooping cough, and B. bronchiseptica, which infects nearly all mammals.
Zachary M. Nash, Carol S. Inatsuka, Peggy A. Cotter, Richard M. Johnson   +3 more
doaj   +2 more sources

Pathogenicity and vaccine protection of circulating pertactin- and filamentous hemagglutinin-deficient Bordetella pertussis strains [PDF]

Emerging Microbes and Infections
The increasing emergence of vaccine antigen-deficient Bordetella pertussis (Bp) variants has raised concerns regarding disease control and prevention. Here, we characterized the pathogenicity and vaccine protection of circulating pertactin-deficient (PRN−
Hanying Dai, Xiuwen Sui, Jie Che, Chunying Zhang, Jiayu Zhao, Jie Li, Bohan Chen, Luyao Guo, Dongshan Yan, Hairui Wang, Xueping Liu, Li Xu, Yuan Gao, Aiping Qin, Tao Zhu, Maojun Zhang, Zhujun Shao   +16 more
doaj   +2 more sources

Multiplexed bead-based assay for the simultaneous quantification of human serum IgG antibodies to tetanus, diphtheria, pertussis toxin, filamentous hemagglutinin, and pertactin [PDF]

Frontiers in Immunology, 2023
BackgroundLuminex bead-based assays offer multiplexing to test antibodies against multiple antigens simultaneously; however, this requires validation using internationally certified reference standards.
Vishal Rathod, Laxmikant Kadam, Manish Gautam, Prabhu Dasu Gumma, Kevin Marke, Cathy Asokanathan, Alex Douglas-Bardsley, Laura Hassell, Sachin Bhandare, Sumit Gupta, Sameer Parekh, Pramod Pujari, Harish Rao, Hitt Sharma, Umesh Shaligram, Sunil Gairola   +15 more
doaj   +2 more sources