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Exploratory Temporal and Evolutionary Insights into the Filoviridae Family Through Multiprotein Phylogeny [PDF]

Microorganisms
Filoviruses are among the most lethal viral human pathogens known, with significant relevance to public health, yet their evolutionary history remains poorly resolved.
Thiago S. Messias, Kaique C. P. Silva, Narciso A. Vieira, Gislaine A. Querino, Elaine C. Marcos, Mateus J. de C. Stefani, Ana P. R. Battochio, Thaís M. Oliveira, Ivan S. Vieira, Aline S. Ibanes, Taylor E. T. Olivo, Edson C. de Melo, Silvia C. Arantes, Pedro C. R. da Luz, Maria G. R. Mengoa, Simone Soares   +15 more
doaj   +5 more sources

Filoviridae: insights into immune responses to Ebola virus [PDF]

Exploration of Immunology
Ebola virus (EBOV) is a zoonotic virus comprising of six known different species, designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an EBOV disease (EVD) was in Yambuku, Zaire EBOV (ZEBOV) in 1976, followed by ...
Brent Brown, Chinua Imarogbe, Enrique Chacon-Cruz, Ingo Fricke   +3 more
doaj   +3 more sources

The New Members of Filoviridae Family: Distribution, Natural Reservoirs, Potential Epidemic Danger

Вестник войск РХБ защиты, 2023
The purpose of the work is to analyze the distribution, natural reservoirs and potential epidemic hazard of new members of the Filoviridae family – Bombali viruses (genus Ebolavirus), Lloviu (genus Cuevavirus), Mengla (genus Dianlovirus), Xylang (genus ...
T. E. Sizikova, N. V. Boyarskaya, A. V. Kovalchuk, V. N. Lebedev, S. V. Borisevich   +4 more
doaj   +4 more sources

ICTV Virus Taxonomy Profile: <i>Filoviridae</i> 2024. [PDF]

J Gen Virol
Filoviridae is a family of negative-sense RNA viruses with genomes of about 13.1-20.9 kb that infect fish, mammals and reptiles. The filovirid genome is a linear, non-segmented RNA with five canonical open reading frames (ORFs) that encode a nucleoprotein (NP), a polymerase cofactor (VP35), a glycoprotein (GP1,2), a transcriptional activator (VP30) and
Biedenkopf N, Bukreyev A, Chandran K, Di Paola N, Formenty PBH, Griffiths A, Hume AJ, Mühlberger E, Netesov SV, Palacios G, Pawęska JT, Smither S, Takada A, Wahl V, Kuhn JH.   +14 more
europepmc   +5 more sources

Bombali virus (Filoviridae: Orthoebolavirus: Orthoebolavirus bombaliense)

Вопросы вирусологии
Introduction. Members of genus Orthoebolavirus of family Filoviridae cause severe hemorrhagic fever in humans with high fatality rates (up to 90%). The first outbreaks of disease caused by the members of genus Orthoebolavirus were registered in 1976 in ...
Tatiana E. Sizikova, Vitaliy N. Lebedev, Sergey V. Borisevich   +2 more
doaj   +3 more sources

Development of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats [PDF]

Viruses, 2023
Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no pan-filovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses.
Jessica Coertse, Marinda Mortlock, Antoinette Grobbelaar, Naazneen Moolla, Wanda Markotter, Jacqueline Weyer   +5 more
doaj   +2 more sources

Filoviridae: Insights into Immune Responses to Ebolavirus

SSRN Electronic Journal, 2023
Ebola virus is a zoonotic virus comprised of 6 different species designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an Ebola virus (EBOV) was in Yambuku, Zaire (ZEBOV) in 1976, followed by Sudan Ebola virus (SUBOV) later that year. Outbreaks have been increasing throughout the 21st century, and mortality rates
Brent Brown
  +8 more sources

Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations

Вопросы вирусологии, 2021
Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the ...
I. V. Dolzhikova, D. N. Shcherbinin, D. Yu. Logunov, A. L. Gintsburg   +3 more
doaj   +3 more sources

Viral diversity in wild rodents in the regions of Canaã de Carajás and Curionopólis, State of Pará, Brazil [PDF]

Frontiers in Microbiology
Wild rodents serve as crucial reservoirs for zoonotic viruses. Anthropogenic and environmental disruptions, particularly those induced by mining activities, can destabilize rodent populations and facilitate the emergence of viral agents. In the Canaã dos
Adriana Freitas Moraes Monteiro, Adriana Freitas Moraes Monteiro, Fábio Silva da Silva, Ana Cecília Ribeiro Cruz, Ana Cecília Ribeiro Cruz, Sandro Patroca da Silva, Alice Louize Nunes Queiroz, Livia Medeiros Neves Casseb, Livia Medeiros Neves Casseb, Livia Carício Martins, Livia Carício Martins, Daniele Barbosa de Almeida Medeiros, Daniele Barbosa de Almeida Medeiros   +12 more
doaj   +2 more sources

Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]

Molecular Aspects of Medicine, 2007
Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
Paolo Ascenzi, Alessio Bocedi, J Heptonstall, Maria Rosaria Capobianchi, Antonino Di, Eloise Mastrangelo, Martino Bolognesi, Giuseppe Ippolito   +7 more
openalex   +10 more sources