Exploratory Temporal and Evolutionary Insights into the Filoviridae Family Through Multiprotein Phylogeny [PDF]
Filoviruses are among the most lethal viral human pathogens known, with significant relevance to public health, yet their evolutionary history remains poorly resolved.
Thiago S. Messias +15 more
doaj +3 more sources
Development of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats [PDF]
Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no pan-filovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses.
Jessica Coertse +5 more
doaj +2 more sources
Filoviridae: insights into immune responses to Ebola virus [PDF]
Ebola virus (EBOV) is a zoonotic virus comprising of six known different species, designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an EBOV disease (EVD) was in Yambuku, Zaire EBOV (ZEBOV) in 1976, followed by ...
Brent Brown +3 more
doaj +2 more sources
The New Members of Filoviridae Family: Distribution, Natural Reservoirs, Potential Epidemic Danger
The purpose of the work is to analyze the distribution, natural reservoirs and potential epidemic hazard of new members of the Filoviridae family – Bombali viruses (genus Ebolavirus), Lloviu (genus Cuevavirus), Mengla (genus Dianlovirus), Xylang (genus ...
T. E. Sizikova +4 more
doaj +3 more sources
Characteristics of the family Filoviridae and the Ebola virus: an update of its implications in the human population The family Filoviridae is integrated by a group of filamentous RNA viruses that cause severe hemorrhagic fevers in primates and other ...
Burgueño-Sosa, E. +3 more
core +3 more sources
Human and murine IFIT1 proteins do not restrict infection of negative-sense RNA viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae families [PDF]
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amarasinghe, Gaya +12 more
core +5 more sources
Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations
Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the ...
I. V. Dolzhikova +3 more
doaj +3 more sources
Bombali virus (Filoviridae: Orthoebolavirus: Orthoebolavirus bombaliense)
Introduction. Members of genus Orthoebolavirus of family Filoviridae cause severe hemorrhagic fever in humans with high fatality rates (up to 90%). The first outbreaks of disease caused by the members of genus Orthoebolavirus were registered in 1976 in ...
Tatiana E. Sizikova +2 more
doaj +2 more sources
Viral diversity in wild rodents in the regions of Canaã de Carajás and Curionopólis, State of Pará, Brazil [PDF]
Wild rodents serve as crucial reservoirs for zoonotic viruses. Anthropogenic and environmental disruptions, particularly those induced by mining activities, can destabilize rodent populations and facilitate the emergence of viral agents. In the Canaã dos
Adriana Freitas Moraes Monteiro +12 more
doaj +2 more sources
Global distribution and genetic diversity of orthoebolaviruses: Mapping and evolutionary analysis [PDF]
Orthoebolavirus genus (Family: Filoviridae) poses an ongoing threat to both human and animal health. To better understand and address this persistent threat, we conducted a comprehensive analysis.
Nuo Cheng +5 more
doaj +2 more sources

