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ICTV Virus Taxonomy Profile: Filoviridae [PDF]
Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of 15–19 kb. Several filoviruses (e.g., Ebola virus) are pathogenic for humans and are highly virulent.
Jens H Kuhn+2 more
exaly +6 more sources
Current perspectives on the phylogeny of Filoviridae
(Uploaded by Plazi for the Bat Literature Project) Sporadic fatal outbreaks of disease in humans and non-human primates caused by Ebola or Marburg viruses have driven research into the characterization of these viruses with the hopes of identifying host tropisms and potential reservoirs.
Roger W Barrette
exaly +4 more sources
ICTV Virus Taxonomy Profile: <i>Filoviridae</i> 2024. [PDF]
Filoviridae is a family of negative-sense RNA viruses with genomes of about 13.1-20.9 kb that infect fish, mammals and reptiles. The filovirid genome is a linear, non-segmented RNA with five canonical open reading frames (ORFs) that encode a nucleoprotein (NP), a polymerase cofactor (VP35), a glycoprotein (GP1,2), a transcriptional activator (VP30) and
Biedenkopf N+14 more
europepmc +5 more sources
Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations [PDF]
The taxonomy of the family Filoviridae (marburgviruses and ebolaviruses) has changed several times since the discovery of its members, resulting in a plethora of species and virus names and abbreviations. The current taxonomy has only been partially accepted by most laboratory virologists.
Jens H Kuhn+2 more
exaly +7 more sources
Filoviridae: Insights into Immune Responses to Ebolavirus
Ebola virus is a zoonotic virus comprised of 6 different species designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an Ebola virus (EBOV) was in Yambuku, Zaire (ZEBOV) in 1976, followed by Sudan Ebola virus (SUBOV) later that year. Outbreaks have been increasing throughout the 21st century, and mortality rates
Brent Brown
+5 more sources
Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]
Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
Paolo Ascenzi+7 more
openalex +11 more sources
Filoviridae: a Taxonomic Home for Marburg and Ebola Viruses ? [PDF]
Michael P. Kiley+16 more
openalex +4 more sources
Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae [PDF]
Jens H Kuhn, Sina Bavari, Stephan Becker
exaly +2 more sources
Developments in Negative-Strand RNA Virus Reverse Genetics [PDF]
Many epidemics are caused by negative-stranded RNA viruses, leading to serious disease outbreaks that threaten human life and health. These viruses also have a significant impact on animal husbandry, resulting in substantial economic losses and ...
Mengyi Wang+6 more
doaj +2 more sources