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ICTV Virus Taxonomy Profile: Filoviridae [PDF]

open access: hybridJournal of General Virology, 2019
Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of 15–19 kb. Several filoviruses (e.g., Ebola virus) are pathogenic for humans and are highly virulent.
Jens H Kuhn   +2 more
exaly   +6 more sources

Current perspectives on the phylogeny of Filoviridae

open access: greenInfection, Genetics and Evolution, 2011
(Uploaded by Plazi for the Bat Literature Project) Sporadic fatal outbreaks of disease in humans and non-human primates caused by Ebola or Marburg viruses have driven research into the characterization of these viruses with the hopes of identifying host tropisms and potential reservoirs.
Roger W Barrette
exaly   +4 more sources

ICTV Virus Taxonomy Profile: <i>Filoviridae</i> 2024. [PDF]

open access: greenJ Gen Virol
Filoviridae is a family of negative-sense RNA viruses with genomes of about 13.1-20.9 kb that infect fish, mammals and reptiles. The filovirid genome is a linear, non-segmented RNA with five canonical open reading frames (ORFs) that encode a nucleoprotein (NP), a polymerase cofactor (VP35), a glycoprotein (GP1,2), a transcriptional activator (VP30) and
Biedenkopf N   +14 more
europepmc   +5 more sources

Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations [PDF]

open access: bronzeArchives of Virology, 2010
The taxonomy of the family Filoviridae (marburgviruses and ebolaviruses) has changed several times since the discovery of its members, resulting in a plethora of species and virus names and abbreviations. The current taxonomy has only been partially accepted by most laboratory virologists.
Jens H Kuhn   +2 more
exaly   +7 more sources

Filoviridae: Insights into Immune Responses to Ebolavirus

open access: greenSSRN Electronic Journal, 2023
Ebola virus is a zoonotic virus comprised of 6 different species designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an Ebola virus (EBOV) was in Yambuku, Zaire (ZEBOV) in 1976, followed by Sudan Ebola virus (SUBOV) later that year. Outbreaks have been increasing throughout the 21st century, and mortality rates
Brent Brown
  +5 more sources

Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]

open access: greenMolecular Aspects of Medicine, 2007
Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
Paolo Ascenzi   +7 more
openalex   +11 more sources

Filoviridae: a Taxonomic Home for Marburg and Ebola Viruses ? [PDF]

open access: bronzeIntervirology, 1982
Michael P. Kiley   +16 more
openalex   +4 more sources

Developments in Negative-Strand RNA Virus Reverse Genetics [PDF]

open access: yesMicroorganisms
Many epidemics are caused by negative-stranded RNA viruses, leading to serious disease outbreaks that threaten human life and health. These viruses also have a significant impact on animal husbandry, resulting in substantial economic losses and ...
Mengyi Wang   +6 more
doaj   +2 more sources

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