Results 11 to 20 of about 6,972 (216)
ICTV Virus Taxonomy Profile: <i>Filoviridae</i> 2024. [PDF]
J Gen VirolFiloviridae is a family of negative-sense RNA viruses with genomes of about 13.1-20.9 kb that infect fish, mammals and reptiles. The filovirid genome is a linear, non-segmented RNA with five canonical open reading frames (ORFs) that encode a nucleoprotein (NP), a polymerase cofactor (VP35), a glycoprotein (GP1,2), a transcriptional activator (VP30) and
Biedenkopf N +14 more
europepmc +5 more sources
Filoviridae: Insights into Immune Responses to Ebolavirus
SSRN Electronic Journal, 2023 Ebola virus is a zoonotic virus comprised of 6 different species designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an Ebola virus (EBOV) was in Yambuku, Zaire (ZEBOV) in 1976, followed by Sudan Ebola virus (SUBOV) later that year. Outbreaks have been increasing throughout the 21st century, and mortality rates
Brent Brown
+8 more sources
Characteristics of Filoviridae: Marburg and Ebola Viruses [PDF]
Naturwissenschaften, 1999 Filoviruses are enveloped, nonsegmented negative-stranded RNA viruses. The two species, Marburg and Ebola virus, are serologically, biochemically, and genetically distinct. Marburg virus was first isolated during an outbreak in Europe in 1967, and Ebola virus emerged in 1976 as the causative agent of two simultaneous outbreaks in southern Sudan and ...
Brigitte Beer +2 more
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Current perspectives on the phylogeny of Filoviridae
Infection, Genetics and Evolution, 2011 (Uploaded by Plazi for the Bat Literature Project) Sporadic fatal outbreaks of disease in humans and non-human primates caused by Ebola or Marburg viruses have driven research into the characterization of these viruses with the hopes of identifying host tropisms and potential reservoirs.
Roger W. Barrette +3 more
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Strategic Preparedness of Broad-Spectrum Antivirals for Rapid Response Towards Next Pandemics. [PDF]
Small SciNanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
N SR, Jin GW, Choy JH.
europepmc +2 more sources
Filoviridae: a Taxonomic Home for Marburg and Ebola Viruses ? [PDF]
Intervirology, 1982 Michael P. Kiley +16 more
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ICTV Virus Taxonomy Profile: Filoviridae [PDF]
Journal of General Virology, 2019 Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of 15–19 kb. Several filoviruses (e.g., Ebola virus) are pathogenic for humans and are highly virulent.
Jens H. Kuhn +22 more
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Molecular Evolution of Viruses of the Family Filoviridae Based on 97 Whole-Genome Sequences [PDF]
Journal of Virology, 2012 ABSTRACT Viruses in the Ebolavirus and Marburgvirus genera (family Filoviridae ) have been associated with large outbreaks of hemorrhagic fever in human and nonhuman primates.
Serena A. Carroll +8 more
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