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ICTV Virus Taxonomy Profile: <i>Filoviridae</i> 2024. [PDF]
Filoviridae is a family of negative-sense RNA viruses with genomes of about 13.1-20.9 kb that infect fish, mammals and reptiles. The filovirid genome is a linear, non-segmented RNA with five canonical open reading frames (ORFs) that encode a nucleoprotein (NP), a polymerase cofactor (VP35), a glycoprotein (GP1,2), a transcriptional activator (VP30) and
Biedenkopf N +14 more
europepmc +5 more sources
Filoviridae: Insights into Immune Responses to Ebolavirus
Ebola virus is a zoonotic virus comprised of 6 different species designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an Ebola virus (EBOV) was in Yambuku, Zaire (ZEBOV) in 1976, followed by Sudan Ebola virus (SUBOV) later that year. Outbreaks have been increasing throughout the 21st century, and mortality rates
Brent Brown
+8 more sources
Developments in Negative-Strand RNA Virus Reverse Genetics [PDF]
Many epidemics are caused by negative-stranded RNA viruses, leading to serious disease outbreaks that threaten human life and health. These viruses also have a significant impact on animal husbandry, resulting in substantial economic losses and ...
Mengyi Wang +6 more
doaj +2 more sources
Characteristics of Filoviridae: Marburg and Ebola Viruses [PDF]
Filoviruses are enveloped, nonsegmented negative-stranded RNA viruses. The two species, Marburg and Ebola virus, are serologically, biochemically, and genetically distinct. Marburg virus was first isolated during an outbreak in Europe in 1967, and Ebola virus emerged in 1976 as the causative agent of two simultaneous outbreaks in southern Sudan and ...
Brigitte Beer +2 more
openalex +3 more sources
Viruses of the Filoviridae family
The article considers representatives of the Filoviridae family, some of which are the causative agents of hemorrhagic fever, which is fatal to humans. The current state of development of immunobiological drugs for the treatment and medical prevention of diseases caused by filoviruses has been analyzed.
A. Chernykh, A. Hancharou
openalex +3 more sources
Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High-Throughput Sequencing Data Mining. [PDF]
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Wang H +19 more
europepmc +2 more sources
Evaluation of Amino Acids Change in Structural Protein of Filoviridae Family during Evolution Process [PDF]
Maryam Mohammadlou, Maryam Mohammadlou
openalex +2 more sources
Filoviridae: a Taxonomic Home for Marburg and Ebola Viruses ? [PDF]
Michael P. Kiley +16 more
openalex +3 more sources

