Results 31 to 40 of about 4,457 (158)

The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent. [PDF]

open access: yesPLoS ONE, 2016
Ebola and marburgviruses, members of the family Filoviridae, can cause severe hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in Western Africa claimed more than 11,300 lives and was associated with secondary cases outside ...
Markus Hoffmann   +4 more
doaj   +1 more source

An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells.

open access: yesPLoS ONE, 2021
Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved.
Yingyun Cai   +5 more
doaj   +1 more source

The West African ebola virus disease epidemic 2014–2015: A commissioned review

open access: yesNigerian Postgraduate Medical Journal, 2016
The first epidemic of Ebola haemorrhagic disease in West Africa is the largest and longest Ebola epidemic till date, where the outbreak notably involved three countries with distant spread to other countries.
S A Omilabu   +3 more
doaj   +1 more source

DYNAMICAL SYSTEM FOR EBOLA OUTBREAK WITHIN QUARANTINE AND VACCINATION TREATMENTS

open access: yesBarekeng, 2023
Ebola Virus Disease (EVD) is an infectious disease with a high mortality rate which is caused by the virus from the family of Filoviridae, genus of Ebolavirus. Therefore, this research works on the developing model of Ebola disease spread with SLSHVEQIHR
Sugian Nurwijaya   +2 more
doaj   +1 more source

Serological Detection of Ebola Virus Exposures in Native Non-human Primates of Southern Nigeria

open access: yesJournal of Epidemiology and Global Health, 2018
Ebola viruses (family: Filoviridae) are the cause of Ebola virus disease (EVD), a highly fatal illness characterised by haemorrhagic fever syndrome in both humans and non-human primates (NHPs).
B.N. Ogunro   +5 more
doaj   +1 more source

Morphologic Differentiation of Viruses beyond the Family Level

open access: yesViruses, 2014
Electron microscopy has been instrumental in the identification of viruses by being able to characterize a virus to the family level. There are a few cases where morphologic or morphogenesis factors can be used to differentiate further, to the genus ...
Cynthia S. Goldsmith
doaj   +1 more source

Viral fossils in marsupial genomes: secret cellular guardians [PDF]

open access: yesMicrobiology Australia, 2021
Genomic viral integrations, termed endogenous viral elements (EVEs), are fragments of viruses in host chromosomes that provide information about viral evolution and could even help protect the host from infection. In the present study we examined EVEs in
Peter A White   +2 more
doaj  

Marburg Virus Reverse Genetics Systems

open access: yesViruses, 2016
The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
doaj   +1 more source

Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing

open access: yesmBio, 2018
Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used cholesterol-lowering drugs, have pleiotropic mechanisms of action and were suggested as potential adjunct ...
Punya Shrivastava-Ranjan   +7 more
doaj   +1 more source

Approaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19

open access: yesFrontiers in Immunology, 2023
Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV) and Marburg virus (MARV), are members of the Filoviridae family that can cause severe disease and death in humans and animals.
Marion F. Gruber   +2 more
doaj   +1 more source

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