Results 31 to 40 of about 4,010 (187)
Evaluation of Amino Acids Change in Structural Protein of Filoviridae Family during Evolution Process [PDF]
Maryam Mohammadlou
openalex +2 more sources
The review presents the following division of the African natural foci province into districts: I. Upper Guinea natural focus region includes the following individual natural foci: I.1. Kazamans; I.2. North Guinea; I.3. Volta; I.4. Adamawa; I.5. Sao Tome. II. Central Africa: II.1. Southern Guinea; II.2. Katanga; II.3. Congo; II.4.
Shchelkanov MIu+7 more
openalex +3 more sources
Long-term survival of an urban fruit bat seropositive for Ebola and Lagos bat viruses. [PDF]
Ebolaviruses (EBOV) (family Filoviridae) cause viral hemorrhagic fevers in humans and non-human primates when they spill over from their wildlife reservoir hosts with case fatality rates of up to 90%.
David T S Hayman+7 more
doaj +1 more source
The role of platelets in the pathogenesis of viral hemorrhagic fevers. [PDF]
Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors that ...
Juan C Zapata+2 more
doaj +1 more source
Marburg virus outbreak in Tanzania: A threat to global health security
Abstract The current Marburg virus (MARV) outbreak in Tanzania served as a stark reminder of the ongoing threat posed by emerging infectious diseases and the urgent need for global health security. The Tanzanian Ministry of Health (MoH) officially declared the outbreak on March 21, 2023.
Majani Edward+6 more
wiley +1 more source
Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair+9 more
doaj +1 more source
Autophagy of the ER: the secretome finds the lysosome
The endoplasmic reticulum (ER) and its components can be targeted to the lysosome for degradation during times of stress or protein misfolding. Recent studies have uncovered multiple distinct pathways that deliver the ER along with its contents to the lysosome, which are collectively referred to as ER‐to‐lysosome‐associated degradation (ERLAD). In this
Jeffrey Knupp+3 more
wiley +1 more source
Virus specific antibody - based remedies for the urgent prevention and treatment of Ebola virus disease [PDF]
The Ebola virus (member of Ebolavirus genus Filoviridae family) is the etiologic agent of extremely hazard human disease with high mortality rates (up to 90%). The most important components of spectrum of therapeutics for special prophylactic and current
T E Sizikova+2 more
doaj +1 more source
The neglected continuously emerging Marburg virus disease in Africa: A global public health threat
Abstract Background and Aim Severe viral hemorrhagic fever (VHF) is caused by Marburg virus which is a member of the Filoviridae (filovirus) family. Many Marburg virus disease (MVD) outbreaks are reported in five decades. A major notable outbreak with substantial reported cases of infections and deaths was in 2022 in Uganda.
Devang Srivastava+12 more
wiley +1 more source
The West African ebola virus disease epidemic 2014–2015: A commissioned review
The first epidemic of Ebola haemorrhagic disease in West Africa is the largest and longest Ebola epidemic till date, where the outbreak notably involved three countries with distant spread to other countries.
S A Omilabu+3 more
doaj +1 more source