Results 11 to 20 of about 4,767 (201)
Correlates of Immunity to Filovirus Infection
Viruses, 2011 Filoviruses can cause severe, often fatal hemorrhagic fever in humans. Recent advances in vaccine and therapeutic drug development have provided encouraging data concerning treatment of these infections.
Sina Bavari, Steven B. Bradfute
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, 2013 A number of advances in recent years have significantly furthered our understanding of filovirus attachment and cellular tropism. For example, several cell-surface molecules have been identified as attachment factors with the potential to facilitate the in vivo targeting of particular cell types such as macrophages and hepatic cells.
Graham Simmons
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Ecologic and Geographic Distribution of Filovirus Disease [PDF]
Emerging Infectious Diseases, 2004 (Uploaded by Plazi for the Bat Literature Project) We used ecologic niche modeling of outbreaks and sporadic cases of filovirus-associated hemorrhagic fever (HF) to provide a large-scale perspective on the geographic and ecologic distributions of Ebola and Marburg viruses.
A. Townsend Peterson +2 more
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Mouse Models for Filovirus Infections [PDF]
Viruses, 2012 The filoviruses marburg- and ebolaviruses can cause severe hemorrhagic fever (HF) in humans and nonhuman primates. Because many cases have occurred in geographical areas lacking a medical research infrastructure, most studies of the pathogenesis of filoviral HF, and all efforts to develop drugs and vaccines, have been carried out in biocontainment ...
Steven B. Bradfute +2 more
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Discovery of an Ebolavirus-Like Filovirus in Europe
PLoS Pathogens, 2011 Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease.
Anabel Negredo +15 more
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Marburg Virus Disease: A Narrative Review. [PDF]
Health Sci RepABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Letafati A +4 more
europepmc +2 more sources
Assembly and transport of filovirus nucleocapsids
PLOS Pathogens, 2022 Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs) located in the perinuclear region. The formation of these IBs is induced mainly by the accumulation of the filoviral nucleoprotein NP, which recruits the other nucleocapsid proteins, the polymerase co-factor VP35, the polymerase L, the transcription factor VP30 and
Olga Dolnik, Stephan Becker
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New filovirus disease classification and nomenclature [PDF]
Nature Reviews Microbiology, 2019 (Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Kuhn, Jens H. +83 more
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AAV Vectored Immunoprophylaxis for Filovirus Infections [PDF]
Tropical Medicine and Infectious Disease, 2020 Filoviruses are among the deadliest infectious agents known to man, causing severe hemorrhagic fever, with up to 90% fatality rates. The 2014 Ebola outbreak in West Africa resulted in over 28,000 infections, demonstrating the large-scale human health and economic impact generated by filoviruses.
Amira D. Rghei +8 more
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Spanner in the works of filovirus infection [PDF]
Nature Reviews Drug Discovery, 2014 Natasha Bray
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