Results 21 to 30 of about 11,014 (267)

Correlates of Immunity to Filovirus Infection

Viruses, 2011
Filoviruses can cause severe, often fatal hemorrhagic fever in humans. Recent advances in vaccine and therapeutic drug development have provided encouraging data concerning treatment of these infections.
Sina Bavari, Steven B. Bradfute
doaj   +3 more sources

Prevalence of human filovirus infections in sub-Saharan Africa: A systematic review and meta-analysis protocol. [PDF]

Syst Rev
Recent outbreaks of Ebola virus disease (EVD) and Marburg virus disease (MVD) in sub-Saharan Africa illustrate the need to better understand animal reservoirs, burden of disease, and human transmission of filoviruses.
Semancik CS, Cooper CL, Postler TS, Price M, Yun H, Zaric M, Kuteesa M, Malkevich N, Kilianski A, Gupta SB, Francis SC.   +10 more
europepmc   +2 more sources

Filovirus infections: science and innovation

Сибирский научный медицинский журнал
Epidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva, V. L. Melnikov, A. V. Arekhina   +2 more
doaj   +2 more sources

Assembly and transport of filovirus nucleocapsids

PLOS Pathogens, 2022
Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs) located in the perinuclear region. The formation of these IBs is induced mainly by the accumulation of the filoviral nucleoprotein NP, which recruits the other ...
O. Dolnik, S. Becker
semanticscholar   +4 more sources

Filovirus VP24 Proteins Differentially Regulate RIG-I and MDA5-Dependent Type I and III Interferon Promoter Activation

Frontiers in Immunology, 2022
Filovirus family consists of highly pathogenic viruses that have caused fatal outbreaks especially in many African countries. Previously, research focus has been on Ebola, Sudan and Marburg viruses leaving other filoviruses less well studied. Filoviruses,
Felix B. He, Hira Khan, Moona Huttunen, Pekka Kolehmainen, Krister Melén, Sari Maljanen, Mengmeng Qu, Miao Jiang, Laura Kakkola, Ilkka Julkunen, Ilkka Julkunen   +10 more
doaj   +2 more sources

Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]

Viruses, 2014
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists. Sequencing duration and costs are rapidly decreasing, sequencing hardware is under modification for use by non-experts, and software is constantly being improved to ...
Jens Kuhn, Kristian Andersen, Yīmíng Bào, Sina Bavari, Stephan Becker, Richard Bennett, Nicholas Bergman, Olga Blinkova, Steven Bradfute, J. Brister, Alexander Bukreyev, Kartik Chandran, Alexander Chepurnov, Robert Davey, Ralf Dietzgen, Norman Doggett, Olga Dolnik, John Dye, Sven Enterlein, Paul Fenimore, Pierre Formenty, Alexander Freiberg, Robert Garry, Nicole Garza, Stephen Gire, Jean-Paul Gonzalez, Anthony Griffiths, Christian Happi, Lisa Hensley, Andrew Herbert, Michael Hevey, Thomas Hoenen, Anna Honko, Georgy Ignatyev, Peter Jahrling, Joshua Johnson, Karl Johnson, Jason Kindrachuk, Hans-Dieter Klenk, Gary Kobinger, Tadeusz Kochel, Matthew Lackemeyer, Daniel Lackner, Eric Leroy, Mark Lever, Elke Mühlberger, Sergey Netesov, Gene Olinger, Sunday Omilabu, Gustavo Palacios, Rekha Panchal, Daniel Park, Jean Patterson, Janusz Paweska, Clarence Peters, James Pettitt, Louise Pitt, Sheli Radoshitzky, Elena Ryabchikova, Erica Saphire, Pardis Sabeti, Rachel Sealfon, Aleksandr Shestopalov, Sophie Smither, Nancy Sullivan, Robert Swanepoel, Ayato Takada, Jonathan Towner, Guido Van der Groen, Viktor Volchkov, Valentina Volchkova, Victoria Wahl-Jensen, Travis Warren, Kelly Warfield, Manfred Weidmann, Stuart Nichol   +75 more
openaire   +9 more sources

Filovirus Entry [PDF]

, 2013
A number of advances in recent years have significantly furthered our understanding of filovirus attachment and cellular tropism. For example, several cell-surface molecules have been identified as attachment factors with the potential to facilitate the in vivo targeting of particular cell types such as macrophages and hepatic cells.
Graham Simmons
openalex   +4 more sources

In Vivo Investigation of Filovirus Glycoprotein-Mediated Infection in a BSL2 Setting. [PDF]

Methods Mol Biol
Richards PT, Briseño JAA, Brunton BA, Maury W.   +3 more
europepmc   +2 more sources

Structural insights into the RNA-dependent RNA polymerase complexes from highly pathogenic Marburg and Ebola viruses [PDF]

Nature Communications
The Ebola and the Marburg viruses belong to the Filoviridae family, a group of filamentous, single-stranded, negative-sensed RNA viruses. Upon infection, uncontrolled propagation of the Ebola and the Marburg viruses causes severe hemorrhagic fevers with ...
Guobao Li, Tianjiao Du, Jiening Wang, Kaiyue Jie, Zhuolu Ren, Xiaokang Zhang, Long Zhang, Shan Wu, Heng Ru   +8 more
doaj   +2 more sources

Mouse Models for Filovirus Infections [PDF]

Viruses, 2012
The filoviruses marburg- and ebolaviruses can cause severe hemorrhagic fever (HF) in humans and nonhuman primates. Because many cases have occurred in geographical areas lacking a medical research infrastructure, most studies of the pathogenesis of filoviral HF, and all efforts to develop drugs and vaccines, have been carried out in biocontainment ...
Steven B. Bradfute, Kelly L. Warfield, Mike Bray   +2 more
openalex   +5 more sources