Results 41 to 50 of about 5,905 (203)
An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures
Viruses, 2012 The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
doaj +1 more source
Potential Mammalian Filovirus Reservoirs
Emerging Infectious Diseases, 2004 (Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Peterson, A. Townsend +3 more
openaire +2 more sources
Development and evaluation of a panel of filovirus sequence capture probes for pathogen detection by next-generation sequencing. [PDF]
PLoS ONE, 2014 A detailed understanding of the circulating pathogens in a particular geographic location aids in effectively utilizing targeted, rapid diagnostic assays, thus allowing for appropriate therapeutic and containment procedures.
Jeffrey W Koehler +10 more
doaj +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Small Science, Volume 6, Issue 1, January 2026.Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
Cellular Factors Implicated in Filovirus Entry [PDF]
Advances in Virology, 2013 Although filoviral infections are still occurring in different parts of the world, there are no effective preventive or treatment strategies currently available against them. Not only do filoviruses cause a deadly infection, but they also have the potential of being used as biological weapons.
Suchita Bhattacharyya, Thomas J. Hope
openaire +3 more sources
BMC Infectious Diseases, 2018 Background Ebolavirus and Marburgvirus are genera of the virus family Filoviridae. Filoviruses cause rare but fatal viral hemorrhagic fevers (VHFs) in remote villages of equatorial Africa with potential for regional and international spread.
Peace Babirye +9 more
doaj +1 more source
ChemistryOpen, Volume 14, Issue 12, December 2025.DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Alaa H. M. Abdelrahman +5 more
wiley +1 more source
Cutaneous manifestations of filovirus infections
International Journal of Dermatology, 2012 AbstractEbolavirus and Marburgvirus, two filoviruses belonging to the Filoviridae family, are among the most virulent pathogens for humans and non‐human primates, causing outbreaks of fulminant hemorrhagic fever (HF) in Central African countries with case fatality rates of up to 90%.
Nkoghe, D. +3 more
openaire +3 more sources
Protein Science, Volume 34, Issue 11, November 2025.Abstract Following the SARS‐CoV‐2 pandemic, many direct‐acting antivirals targeting viral cysteine protease were developed. SARS‐CoV‐2, as well as other viruses, rely on cysteine proteases for their replication, suggesting future generations of antivirals targeting cysteine proteases will emerge.
Zoe Turner +9 more
wiley +1 more source
Human Vaccines, 2011 Filoviruses can cause severe and often fatal hemorrhagic fever in humans and non-human primates (NHPs). Although there are currently no clinically proven treatments for filovirus disease, much progress has been made in recent years in the discovery of therapeutics and vaccines against these viruses.
Steven B, Bradfute +2 more
openaire +2 more sources