Results 61 to 70 of about 9,370 (262)
Rapid bedside inactivation of Ebola virus for safe nucleic acid tests [PDF]
, 2016 Rapid bedside inactivation of Ebola virus would be a solution for the safety of medical and technical staff, risk containment, sample transport and high-throughput or rapid diagnostic testing during an outbreak.
Bragstad, Karoline +9 more
core +1 more source
Clinical Management of Filovirus-Infected Patients
Viruses, 2012 Filovirus infection presents many unique challenges to patient management. Currently no approved treatments are available, and the recommendations for supportive care are not evidence based.
Danielle V. Clark +2 more
doaj +1 more source
Viewpoint: filovirus haemorrhagic fever outbreaks: much ado about nothing? [PDF]
, 2000 The recent outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo has put the filovirus threat back on the international health agenda.
Boelaert, M +7 more
core +3 more sources
Viruses, 2019 Macrophages are one of the first and also a major site of filovirus replication and, in addition, are a source of multiple cytokines, presumed to play a critical role in the pathogenesis of the viral infection. Some of these cytokines are known to induce
Tzanko S. Stantchev +5 more
doaj +1 more source
Ad35 and ad26 vaccine vectors induce potent and cross-reactive antibody and T-cell responses to multiple filovirus species. [PDF]
PLoS ONE, 2012 Filoviruses cause sporadic but highly lethal outbreaks of hemorrhagic fever in Africa in the human population. Currently, no drug or vaccine is available for treatment or prevention.
Roland Zahn +14 more
doaj +1 more source
Cellular Factors Implicated in Filovirus Entry [PDF]
Advances in Virology, 2013 Although filoviral infections are still occurring in different parts of the world, there are no effective preventive or treatment strategies currently available against them. Not only do filoviruses cause a deadly infection, but they also have the potential of being used as biological weapons.
Suchita Bhattacharyya, Thomas J. Hope
openaire +4 more sources
Filovirus Replication and Transcription [PDF]
Future Virology, 2007 The highly pathogenic filoviruses, Marburg and Ebola virus, belong to the nonsegmented negative-sense RNA viruses of the order Mononegavirales. The mode of replication and transcription is similar for these viruses. On one hand, the negative-sense RNA genome serves as a template for replication, to generate progeny genomes, and, on the other hand, for ...
openaire +3 more sources
Filovirus Mimics Deliver Effectively [PDF]
Biophysical Journal, 2016 Filoviruses such as Ebola are microns long but biophysical advantages for such encapsulating/enveloped viruses have remained obscure. Flexible ‘filomicelles’ have been made from amphiphilic block copolymers and demonstrate effective delivery of two very different hydrophobic compounds.
Afsaneh Lavasanifar +4 more
openaire +2 more sources
Marburg virus survivor immune responses are Th1 skewed with limited neutralizing antibody responses. [PDF]
, 2017 Until recently, immune responses in filovirus survivors remained poorly understood. Early studies revealed IgM and IgG responses to infection with various filoviruses, but recent outbreaks have greatly expanded our understanding of filovirus immune ...
Agrati +54 more
core +4 more sources
Vaccines, 2020 In the infectious diseases field, protective immunity against individual virus species or strains does not always confer cross-reactive immunity to closely related viruses, leaving individuals susceptible to disease after exposure to related virus ...
Sarah Sebastian +11 more
doaj +1 more source