Results 61 to 70 of about 5,905 (203)
Filovirus Mimics Deliver Effectively [PDF]
Biophysical Journal, 2016 Filoviruses such as Ebola are microns long but biophysical advantages for such encapsulating/enveloped viruses have remained obscure. Flexible ‘filomicelles’ have been made from amphiphilic block copolymers and demonstrate effective delivery of two very different hydrophobic compounds.
Nair, Praful R. +4 more
openaire +1 more source
From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis
Microbial Biotechnology, Volume 18, Issue 7, July 2025.Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley +1 more source
Intracellular Events and Cell Fate in Filovirus Infection
Viruses, 2011 Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Elena Ryabchikova +3 more
doaj +1 more source
Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis)
Journal of Fish Diseases, EarlyView.
Johanna Perschthaler +4 more
wiley +1 more source
Terpenes and Terpenoids: How can we use them?
European Journal of Organic Chemistry, Volume 28, Issue 24, June 24, 2025.The transition from petroleum‐based to renewable bio‐based chemicals has led to increased interest in terpenes and terpenoids. This overview highlights their chemistry, focusing on their reactivity and applications in polymerizations, total syntheses, pharmaceuticals, and bio‐based chemical conversions; promoting sustainable and green chemical ...
Jay Hanssens +3 more
wiley +1 more source
Land Use Change and Infectious Disease Emergence
Reviews of Geophysics, Volume 63, Issue 2, June 2025.Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli +6 more
wiley +1 more source
Animal models for filovirus infections.
Zoological research, 2018 The family Filoviridae, which includes the genera Marburgvirus and Ebolavirus, contains some of the most pathogenic viruses in humans and non-human primates (NHPs), causing severe hemorrhagic fevers with high fatality rates. Small animal models against filoviruses using mice, guinea pigs, hamsters, and ferrets have been developed with the goal of ...
Siragam, Vinayakumar +2 more
openaire +2 more sources
Possible leap ahead in filovirus therapeutics [PDF]
Cell Research, 2014 In a recent study published in Nature, Warren et al. describe the generation of a novel synthetic adenosine analogue, BCX4430, a synthetic drug-like small molecule that provides protection from Ebola and Marburg virus infection in animal models.
Darryl, Falzarano, Heinz, Feldmann
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Nature Communications, 2023 Marburg and Ebola filoviruses are two of the deadliest infectious agents and several outbreaks have occurred in the last decades. Although several receptors and co-receptors have been reported for Ebola virus, key host factors remain to be elucidated. In
Vanessa Monteil +23 more
doaj +1 more source
Filovirus Neutralising Antibodies: Mechanisms of Action and Therapeutic Application [PDF]
, 2021 Alexander Hargreaves +5 more
openalex +1 more source