Results 81 to 90 of about 5,905 (203)

Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine.

PLoS Pathogens, 2019
There are a number of vaccine candidates under development against a small number of the most common outbreak filoviruses all employing the virus glycoprotein (GP) as the vaccine immunogen.
Md Niaz Rahim, Edmund G Wee, Shihua He, Jonathan Audet, Kevin Tierney, Nathifa Moyo, Zara Hannoun, Alison Crook, Andrea Baines, Bette Korber, Xiangguo Qiu, Tomáš Hanke   +11 more
doaj   +1 more source

Filoviruses: One of These Things is (not) Like the Other

Viruses, 2015
The family Filoviridae contains several of the most deadly pathogens known to date and the current Ebola virus disease (EVD) outbreak in Western Africa, due to Ebola virus (EBOV) infection, highlights the need for active and broad research into filovirus
Scott M. Anthony, Steven B. Bradfute
doaj   +1 more source

Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir

Viruses, 2019
The 2014 Ebolavirus outbreak in West Africa highlighted the need for vaccines and therapeutics to prevent and treat filovirus infections. A well-characterized small animal model that is susceptible to wild-type filoviruses would facilitate the screening ...
Jason E. Comer, Olivier Escaffre, Natasha Neef, Trevor Brasel, Terry L. Juelich, Jennifer K. Smith, Jeanon Smith, Birte Kalveram, David D. Perez, Shane Massey, Lihong Zhang, Alexander N. Freiberg   +11 more
doaj   +1 more source

Evasion of the Interferon-Mediated Antiviral Response by Filoviruses

Viruses, 2010
The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Washington B. Cárdenas
doaj   +1 more source

Broad‐Spectrum Antiviral Activity of the Orally Bioavailable Antiviral ATV014 Against Multiple Coronaviruses

MedComm, Volume 6, Issue 5, May 2025.
Sidi Yang, Kun Li, Qifan Zhou, Xumu Zhang, Deyin Guo   +4 more
wiley   +1 more source

Generation, Epitope swapping and stability studies of Filovirus pseudotypes and their utilisation in specific antibody assays

, 2021
Martin Mayora Neto
openalex   +1 more source

Peripheral immune responses to filoviruses in a reservoir versus spillover hosts reveal transcriptional correlates of disease

Frontiers in Immunology
Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no overt illness upon natural or ...
Jonathan C. Guito, Catherine E. Arnold, Catherine E. Arnold, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, Jessica R. Spengler, Jessica R. Harmon, Joann D. Coleman-McCray, Mariano Sanchez-Lockhart, Gustavo F. Palacios, Jonathan S. Towner, Joseph B. Prescott, Joseph B. Prescott   +13 more
doaj   +1 more source

Doença Causada por Filovírus: Uma Atualização

Acta Médica Portuguesa
Os vírus Marburgo e Ébola pertencem à família Filoviridae e são conhecidos por causar doenças zoonóticas emergentes. Estes vírus apresentam alta letalidade e são facilmente transmissíveis de pessoa para pessoa, o que os torna potencialmente capazes de ...
Rafael Marx de Andrade, Andreia Paulos, Emília Valadas, Vitor Laerte Pinto Junior   +3 more
doaj   +1 more source

A Limited Structural Modification Results in a Significantly More Efficacious Diazachrysene-Based Filovirus Inhibitor [PDF]

, 2012
Života Selaković, Dejan Opsenica, Brett Eaton, Cary Retterer, Sina Bavari, James C. Burnett, Bogdan A. Šolaja, Rekha G. Panchal   +7 more
openalex   +1 more source

Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein

, 2020
Yinyi Gao, Han Cheng, Sameer Ullah Khan, Gaokeng Xiao, Lijun Rong, Chuan Bai   +5 more
openalex   +2 more sources