Results 81 to 90 of about 4,767 (201)
Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir
Viruses, 2019 The 2014 Ebolavirus outbreak in West Africa highlighted the need for vaccines and therapeutics to prevent and treat filovirus infections. A well-characterized small animal model that is susceptible to wild-type filoviruses would facilitate the screening ...
Jason E. Comer +11 more
doaj +1 more source
Evasion of the Interferon-Mediated Antiviral Response by Filoviruses
Viruses, 2010 The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Washington B. Cárdenas
doaj +1 more source
Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors
Cell Reports, 2018 Summary: Some monoclonal antibodies (mAbs) recovered from survivors of filovirus infections can protect against infection. It is currently unknown whether natural infection also induces some antibodies with the capacity for antibody-dependent enhancement
Natalia A. Kuzmina +10 more
doaj
Viruses, 2014 Understanding human filovirus hemorrhagic fever (FHF) clinical manifestations and evaluating treatment strategies require the collection of clinical data in outbreak settings, where clinical documentation has been limited.
Silja Bühler +3 more
doaj +1 more source
104. Filovirus-Pseudotyped Lentiviral-Mediated Gene Transfer in Human Fetal Tracheal Xenografts [PDF]
, 2002 openalex +1 more source
Genetics-Based Classification of Filoviruses Calls for Expanded Sampling of Genomic Sequences
Viruses, 2012 We have recently developed a computational approach for hierarchical, genome-based classification of viruses of a family (DEmARC). In DEmARC, virus clusters are delimited objectively by devising a universal family-wide threshold on intra-cluster genetic ...
Alexander E. Gorbalenya, Chris Lauber
doaj +1 more source
Identification d’un co-facteur pour l’entrée des filovirus Ebola et Marburg [PDF]
, 2002 Sylvain Baize, Vincent Deubel
openalex +1 more source
Frontiers in ImmunologySeveral filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no overt illness upon natural or ...
Jonathan C. Guito +13 more
doaj +1 more source
Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells
mBio, 2014 Deep sequencing of RNAs produced by Zaire ebolavirus (EBOV) or the Angola strain of Marburgvirus (MARV-Ang) identified novel viral and cellular mechanisms that diversify the coding and noncoding sequences of viral mRNAs and genomic RNAs.
Reed S. Shabman +7 more
doaj +1 more source