Novel filoviruses: indication of a global threat or cause to reassess our risk perception? [PDF]
npj VirusesFiloviruses such as Ebola virus are widely known as causative agents of severe human disease, although apathogenic filoviruses also exist. There is now increasing evidence that filoviruses circulate in almost all parts of the world, where they are being ...
Allison Groseth, Thomas Hoenen
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Non-Ebola Filoviruses: Potential Threats to Global Health Security [PDF]
VirusesFiloviruses are negative-sense single-stranded RNA viruses often associated with severe and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality rates as high as 90%.
Yannick Munyeku-Bazitama +2 more
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Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines
Pathogens, 2022 Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection, they can cause life-threatening symptoms such as inflammation, tissue damage,
Jianlin Lu +2 more
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Filoviruses are ancient and integrated into mammalian genomes [PDF]
BMC Evolutionary Biology, 2010 Background Hemorrhagic diseases from Ebolavirus and Marburgvirus (Filoviridae) infections can be dangerous to humans because of high fatality rates and a lack of effective treatments or vaccine.
Bruenn Jeremy +2 more
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One-for-one or one-for-all? Considerations for filovirus vaccine development. [PDF]
PLoS BiologyFiloviruses continue to re-emerge in Africa, causing localized public health emergencies. Although vaccination has slowly been implemented for Ebola virus, not for other filoviruses, holistic approaches are needed to broadly protect against filovirus ...
Andrea Marzi
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Virucidal Approaches for Hemorrhagic Fever Viruses [PDF]
VirusesWe have reviewed the primary literature on the virucidal efficacy of microbicidal active ingredients, formulated microbicides, and physical inactivation approaches (heat, irradiation) for hemorrhagic fever viruses (HFVs) (arenaviruses, filoviruses ...
Raymond W. Nims, M. Khalid Ijaz
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The New Members of Filoviridae Family: Distribution, Natural Reservoirs, Potential Epidemic Danger
Вестник войск РХБ защиты, 2023 The purpose of the work is to analyze the distribution, natural reservoirs and potential epidemic hazard of new members of the Filoviridae family – Bombali viruses (genus Ebolavirus), Lloviu (genus Cuevavirus), Mengla (genus Dianlovirus), Xylang (genus ...
T. E. Sizikova +4 more
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Serological Evidence of Filovirus Infection in Nonhuman Primates in Zambia
Viruses, 2021 Ebolaviruses and marburgviruses are filoviruses that are known to cause severe hemorrhagic fever in humans and nonhuman primates (NHPs). While some bat species are suspected to be natural reservoirs of these filoviruses, wild NHPs often act as ...
Katendi Changula +9 more
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Animal Model Alternatives in Filovirus and Bornavirus Research
Viruses, 2023 The order Mononegavirales contains a variety of highly pathogenic viruses that may infect humans, including the families Filoviridae, Bornaviridae, Paramyxoviridae, and Rhabodoviridae.
Lina Widerspick +3 more
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The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent. [PDF]
PLoS ONE, 2016 Ebola and marburgviruses, members of the family Filoviridae, can cause severe hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in Western Africa claimed more than 11,300 lives and was associated with secondary cases outside ...
Markus Hoffmann +4 more
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