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(Uploaded by Plazi for the Bat Literature Project) Eight viruses are currently assigned to the family Filoviridae. Marburg virus, Sudan virus and, in particular, Ebola virus have received the most attention both by researchers and the public from 1967 to 2013.
Robin Burk +8 more
openalex +3 more sources
Filoviruses (Ebola and Marburg viruses) cause severe hemorrhagic fever in humans and nonhuman primates. No effective prophylaxis or treatment for filovirus diseases is yet commercially available. Recent studies have advanced our knowledge of filovirus protein functions and interaction between viral and host factors in the replication cycle.
Ron H. Rawlings +15 more
+7 more sources
Animal Model Alternatives in Filovirus and Bornavirus Research
The order Mononegavirales contains a variety of highly pathogenic viruses that may infect humans, including the families Filoviridae, Bornaviridae, Paramyxoviridae, and Rhabodoviridae.
Lina Widerspick +3 more
doaj +1 more source
The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent. [PDF]
Ebola and marburgviruses, members of the family Filoviridae, can cause severe hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in Western Africa claimed more than 11,300 lives and was associated with secondary cases outside ...
Markus Hoffmann +4 more
doaj +1 more source
Development of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats
Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no pan-filovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses.
Jessica Coertse +5 more
doaj +1 more source
(Uploaded by Plazi for the Bat Literature Project) While Reston and Lloviu viruses have never been associated with human disease, the other filoviruses cause outbreaks of hemorrhagic fever characterised by person-to-person transmission and high case fatality ratios.
Amy J, Schuh +2 more
openaire +2 more sources
Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism
Summary: Fruit bats are suspected to be natural hosts of filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV). Interestingly, however, previous studies suggest that these viruses have different tropisms depending on the bat species.
Yoshihiro Takadate +15 more
doaj +1 more source

