Results 41 to 50 of about 5,486 (195)
Viruses, 2022 The Ebola virus has caused outbreaks in Central and West Africa, with high rates of morbidity and mortality. Clinical trials of recombinant virally vectored vaccines did not explicitly include pregnant or nursing women, resulting in a gap in knowledge of
Caitlin A. Williams +4 more
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Organoid Models to Study Human Infectious Diseases
Cell Proliferation, Volume 58, Issue 11, November 2025.Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
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Проблемы особо опасных инфекций, 2018 Among the viruses transmitted by Chiroptera, filoviruses, lissaviruses, henipaviruses, and coronaviruses pose the major threat to humans. The featured review is devoted to the analysis of the results of studies on the role of African Chiropterans in the ...
A. M. Porshakov +3 more
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Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health
Microbial Biotechnology, Volume 18, Issue 9, September 2025.Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Harald Brüssow
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Filoviruses in Bats: Current Knowledge and Future Directions
Viruses, 2014 Filoviruses, including Ebolavirus and Marburgvirus, pose significant threats to public health and species conservation by causing hemorrhagic fever outbreaks with high mortality rates. Since the first outbreak in 1967, their origins, natural history, and
Kevin J. Olival, David T. S. Hayman
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The Antiviral Activity of Polyphenols
Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard +5 more
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Emerging virus diseases: can we ever expect the unexpected?
Emerging Microbes and Infections, 2012 Emerging virus diseases are a major threat to human and veterinary public health. With new examples occurring approximately one each year, the majority are viruses originating from an animal host.
Colin R Howard, Nicola F Fletcher
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General remarks of the secondary promoter element regulating the genome replication of paramyxo- and filoviruses [PDF]
, 2023 Shoichi Ashida +5 more
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Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology
Annals of the New York Academy of Sciences, Volume 1550, Issue 1, Page 151-172, August 2025.Bats are recognized to have distinct immune systems from other vertebrates that may allow them to host virulent pathogens without showing disease. However, these flying mammals are also incredibly diverse, such that bats should not be expected to be immunologically homogenous.
Daniel J. Becker +11 more
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Genetics-Based Classification of Filoviruses Calls for Expanded Sampling of Genomic Sequences
Viruses, 2012 We have recently developed a computational approach for hierarchical, genome-based classification of viruses of a family (DEmARC). In DEmARC, virus clusters are delimited objectively by devising a universal family-wide threshold on intra-cluster genetic ...
Alexander E. Gorbalenya, Chris Lauber
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