Results 81 to 90 of about 9,748 (234)

Introducing EbolaCheck: potential for point-of-need infectious disease diagnosis [PDF]

, 2015
The 2013–2015 Ebolavirus disease humanitarian crisis has spurred the development of laboratory-free, point-of-care nucleic acid testing solutions.
Christie A, Mather ST, Moreau M, Pasloske BL, Regules JA, Spengler JR, Sterghios Athanasios Moschos   +6 more
core   +1 more source

Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology

Annals of the New York Academy of Sciences, Volume 1550, Issue 1, Page 151-172, August 2025.
Bats are recognized to have distinct immune systems from other vertebrates that may allow them to host virulent pathogens without showing disease. However, these flying mammals are also incredibly diverse, such that bats should not be expected to be immunologically homogenous.
Daniel J. Becker, Amanda Vicente‐Santos, Ashley B. Reers, B. R. Ansil, Mika O'Shea, Caroline A. Cummings, Alicia J. Roistacher, Rita M. Quintela‐Tizon, Manuela M. T. Pereira, Juniper Rosen, Arinjay Banerjee, Hannah K. Frank   +11 more
wiley   +1 more source

Filoviruses Use the HOPS Complex and UVRAG To Traffic to Niemann-Pick C1 Compartments during Viral Entry

Journal of Virology, 2020
Ebola viruses (EBOV) and other filoviruses cause sporadic and unpredictable outbreaks of highly lethal diseases. The lack of FDA-approved therapeutics, particularly ones with panfiloviral specificity, highlights the need for continued research efforts to
Yuxia Bo, S. Qiu, Rory P. Mulloy, M. Côté   +3 more
semanticscholar   +1 more source

Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses [PDF]

, 2006
Ebola and Marburg viruses can cause hemorrhagic fever (HF) outbreaks with high mortality in primates. Whereas Marburg (MARV), Ebola Zaire (ZEBOV), and Ebola Sudan (SEBOV) viruses are pathogenic in humans, apes, and monkeys, Ebola Reston (REBOV) is ...
Chen, Ivy, Lipkin, W. Ian, Nichol, Stuart T., Palacios, Gustavo F., Sariol, Carlos A., Towner, Jonathan S., Yaddanapudi, Kavitha   +6 more
core   +3 more sources

Exploring Therapeutic Targets From Spreading Patterns Against Respiratory Syncytial Virus

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
RSV spreads through three main modes of infection: receptor‐dependent infection of free viral particles, syncytia formation, and transmission via actin filaments. CX3CR1, CCR3, and HSPG mediate viral adsorption; the IGF1R signaling pathway facilitates viral internalization by recruiting NCL to the membrane surface, and the RHO GTPase and PI3K signaling
Han Zhang, Zhao Zhang, Yixuan Yang, Jingjing Pei   +3 more
wiley   +1 more source

Seroreactive Profiling of Filoviruses in Chinese Bats Reveals Extensive Infection of Diverse Viruses

Journal of Virology, 2020
Bats are natural hosts of many FiVs, from which diverse FiVs were serologically or virologically detected in Africa, Europe, and East Asia. Recently, very divergent FiVs were identified in the Chinese bat population, but their antigenic relationship with
Chang Zhang, Zhongyi Wang, Jianqiu Cai, Xiaomin Yan, Fuqiang Zhang, Jianmin Wu, Lin Xu, Zongzheng Zhao, T. Hu, C. Tu, B. He   +10 more
semanticscholar   +1 more source

From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis

Microbial Biotechnology, Volume 18, Issue 7, July 2025.
Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley   +1 more source

Temporal and spatial limitations in global surveillance for bat filoviruses and henipaviruses

bioRxiv, 2019
Sampling reservoir hosts over time and space is critical to detect epizootics, predict spillover, and design interventions. However, because sampling is logistically difficult and expensive, researchers rarely perform spatiotemporal sampling of many ...
Daniel J. Becker, D. Crowley, A. Washburne, R. Plowright   +3 more
semanticscholar   +1 more source

The vaccines based on the replicon of the venezuelan equine encephalomyelitis virus against viral hemorrhagic fevers

Вопросы вирусологии, 2015
The status of the various recombinant DNA and RNA-derived candidate vaccines, as well as the Venezuelan equine encephalomyelitis virus (VEEV) replicon vaccine system against extremely hazardous viral hemorrhagic fevers, were reviewed.
A. A. Petrov, T. M. Plekhanova, O. N. Sidorova, S. V. Borisevich, A. A. Makhlay   +4 more
doaj  

Terpenes and Terpenoids: How can we use them?

European Journal of Organic Chemistry, Volume 28, Issue 24, June 24, 2025.
The transition from petroleum‐based to renewable bio‐based chemicals has led to increased interest in terpenes and terpenoids. This overview highlights their chemistry, focusing on their reactivity and applications in polymerizations, total syntheses, pharmaceuticals, and bio‐based chemical conversions; promoting sustainable and green chemical ...
Jay Hanssens, Diego Meneses, Jordy M. Saya, Romano V. A. Orru   +3 more
wiley   +1 more source