Results 91 to 100 of about 517,787 (283)

QINGYAMIN/Code-flash-drought: Accelerating onset of flash droughts

, 2022
Accelerating onset of flash droughts induced by the joint influence of soil moisture depletion and atmospheric ...
QINGYAMIN
core   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science
Radiation therapy (RT) is essential for treating thoracic malignancies but often causes significant lung damage. FLASH‐RT, an ultra‐high dose rate irradiation technique, shows potential in reducing radiation‐induced lung injury (RILI) while maintaining ...
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
doaj   +1 more source

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

Advanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu   +11 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Tissue-specific iron levels modulate lipid peroxidation and the FLASH radiotherapy effect

Cell Death and Disease
Iron is vital to living cells, playing a key role in cellular respiration, DNA synthesis, and various metabolic functions. Importantly, cancer cells have a higher dependency on iron compared to normal cells to support their rapid growth and survival. Due
Nuria Vilaplana-Lopera, Jiyoung Kim, Gilyeong Nam, Iain D. C. Tullis, Salome Paillas, Jia-Ling Ruan, Pei Ju Lee, Yanyan Jiang, Sohee Park, Tianxu Hou, Ayesha Nasir, Eve Charlesworth, Ellie Walker, Ammar Abu-Halawa, Mark A. Hill, Changhoon Choi, Ik Jae Lee, Youngtae Jeong, Samira Lakhal-Littleton, Chee Kin Then, Shing-Chuan Shen, Amato J. Giaccia, Kristoffer Petersson, Eui Jung Moon   +23 more
doaj   +1 more source

The influence of beam parameters on FLASH effect

Frontiers in Oncology
Ultra-high dose rate radiotherapy (FLASH-RT) is typically defined as an external beam radiotherapy that utilizes a dose rate of 40 Gy/s or higher, compared with conventional dose rate radiotherapy (≤0.1 Gy/s).
Binwei Lin, Binwei Lin, Huan Du, Huan Du, Xiaofei Hao, Xiaofei Hao, Yuwen Liang, Haonan Xu, Wenqiang Tang, Jie Li, Jie Li, Yu Zhang, Yu Zhang, Xiao Bo Du, Xiao Bo Du, Xiao Bo Du   +15 more
doaj   +1 more source

Anatomy of extraordinary rainfall and flash flood in a Dutch lowland catchment [PDF]

, 2011
On 26 August 2010 the eastern part of The Netherlands and the bordering part of Germany were struck by a series of rainfall events lasting for more than a day.
van der Velde, Y., A. Overeem, Y. van der Velde, Teuling, R., Brauer, C.C., Warmerdam, P. M. M., P. Hazenberg, A. J. Teuling, Van Der Velde, Y.; id_orcid, Overeem, A., Hazenberg, P., C. C. Brauer, Uijlenhoet, R., Brauer, C. C., Warmerdam, P. M.M., Teuling, A. J., Velde, Y., van der, P. M. M. Warmerdam, Warmerdam, P.M.M., van der Velde, Y.,, R. Uijlenhoet   +20 more
core   +1 more source

RT-PCR and RT-ddPCR primers.

, 2023
Abbreviations: F, forward; R, reverse; RT-PCR, reverse transcription-PCR; RT-ddPCR, reverse transcription-droplet digital PCR. (XLSX)
Patrizia Luppi (15307197), Peter Drain (15307200), Erik A. Koppes (15307191), Donna B. Stolz (6901796), John R. Yates III (8072333), Robert D. Nicholls (15307203), Hyun Jung Park (8778488), James J. Moresco (569744), Dale W. Lewis (6862094), Jolene K. Diedrich (1235706), Susanne M. Gollin (5063618), Simon C. Watkins (39900), Ronald C. Wek (15169871), Marie A. Johnson (15307194)   +13 more
core   +1 more source

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

Advanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang, Yuxiang Ren, Shofarul Wustoni, Atheer Alqatari, Adel Hama, Yazhou Wang, Long Chen, Jessica Parrado Agudelo, Luca Salvigni, Keying Guo, Ashraf Dada, Stefan T. Arold, Raik Grünberg, Sahika Inal   +13 more
wiley   +1 more source