Results 81 to 90 of about 517,787 (283)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Flash Flood Assessment for Wadi Mousa City-Jordan

, 2014
This paper aims to assess risks due to potential Flash Floods hazards in Wadi Mousa and to determine the magnitude of flows for flash flood hazards and construct Floodplain Zone maps for the selected flood return periods of 25, 50, 75 and 100 years. Wadi
Alhasanat, H., Amaratunga, Dilanthi
core   +1 more source

Using SMS text messaging for teaching and data collection in the behavioral sciences [PDF]

, 2009
Recent interest in university teaching has focused on interactivity in lectures and practical classes, and teachers in several fields have set up systems in which students can interact with the lecturer using mobile-phone-based SMS text messaging.
Stewart, N., Stewart, Neil, Reimers, S.J., Reimers, Stian   +3 more
core   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Mechanisms of Action in FLASH Radiotherapy: A Comprehensive Review of Physicochemical and Biological Processes on Cancerous and Normal Cells

Cells
The advent of FLASH radiotherapy (FLASH-RT) has brought forth a paradigm shift in cancer treatment, showcasing remarkable normal cell sparing effects with ultra-high dose rates (>40 Gy/s).
James C. L. Chow, Harry E. Ruda
doaj   +1 more source

Mapping RT-LOTOS specifications into Time Petri Nets [PDF]

, 2006
RT-LOTOS is a timed process algebra which enables compact and abstract specification of real-time systems. This paper proposes and illustrates a structural translation of RT-LOTOS terms into behaviorally equivalent (timed bisimilar) finite Time Petri ...
Boyer, Marc, Sadani, Tarek, Courtiat, Jean-Pierre, Jean-Pierre Courtiat, Tarek Sadani, Saqui-Sannes, Pierre de, Pierre de Saqui-Sannes, Marc Boyer   +7 more
core   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Towards Clinical Translation: Establishing Optimal Dose and Dose-Rate Parameters for the FLASH Skin-Sparing Effect

Dose-Response
Purpose FLASH radiotherapy (FLASH-RT) has been reported to spare skin from acute radiation toxicity. However, systematic quantification is needed to determine the dose and dose-rate thresholds necessary for optimal radioprotection in FLASH radiotherapy ...
Yufeng Shen, Jie Zhou, Jinyi Lang, Lintao Li, Yongjie Li, Chenxi Yang, Shuo Wang, Xiaohua Chen, Siyu Xie, Wei Tang, Shun Lu   +10 more
doaj   +1 more source

Az Adobe Flash technika [PDF]

, 2009
A Flash technika ismertetése.
Dulai, József
core