Results 101 to 110 of about 517,787 (283)
ObjectivesThis study preliminarily examines the potential correlation between the gut microbiome and the protective effects of FLASH radiotherapy (FLASH-RT) on intestinal tissue using metagenomic analysis.MethodsCompact single high-energy X-ray source ...
Huan Du +27 more
doaj +1 more source
Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley +1 more source
Knowledge of, and response to, upland flash flooding: a case study of flood risk management of the 2005 flash flood in upper Ryedale, North Yorkshire, U.K. [PDF]
The dangerous hazard posed by flash flooding to upland communities is likely to increase due to climate change. The flood risk management policy approach has become predominant since the 1990s, with an emphasis on the public awareness of, and responses ...
HOPKINS, JONATHAN
core
Evaluation of Flash Drought Criteria Components [PDF]
Flash droughts occur rapidly (approximately 1 month timescale) and have produced significant ecological, agricultural, and socioeconomical impacts. Recent advances in our understanding of flash droughts have resulted in methods to identify and quantify ...
Edris, Stuart
core
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci +13 more
wiley +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang +10 more
wiley +1 more source
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Fred D. White, Writing Flash: How to Craft and Publish Flash Fiction for a Booming Market [review] [PDF]
Review of Fred D. White's Writing Flash: How to Craft & Publish Flash Fiction for a Booming Market (Fresno: Quill Driver, 2018 ...
Chantler, Ashley
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