Radiobiology and treatment plan progress of FLASH radiotherapy
Fushe yanjiu yu fushe gongyi xuebao, 2023 FLASH radiotherapy is a novel method that has the potential to improve the therapeutic gain ratio to a new level. FLASH radiotherapy technology is mainly characterized by irradiation at ultra-high dose rate, which can reduce radiation-induced injury to ...
WU Xun +3 more
doaj +2 more sources
Flash Radiotherapy: Innovative Cancer Treatment [PDF]
Encyclopedia, 2023 Flash radiotherapy (Flash-RT) is an innovative technique used in radiotherapy for cancer treatment because it delivers an extremely high dose of radiation (>40 Gy/s) to the tumour in a very short period of time, typically within a fraction of a second ...
James C. L. Chow, Harry E. Ruda
doaj +2 more sources
Translational Research in FLASH Radiotherapy—From Radiobiological Mechanisms to In Vivo Results
Biomedicines, 2021 FLASH radiotherapy, or the administration of ultra-high dose rate radiotherapy, is a new radiation delivery method that aims to widen the therapeutic window in radiotherapy.
Loredana G. Marcu +3 more
doaj +2 more sources
Electron FLASH radiotherapy in vivo studies. A systematic review [PDF]
Frontiers in OncologyFLASH-radiotherapy delivers a radiation beam a thousand times faster compared to conventional radiotherapy, reducing radiation damage in healthy tissues with an equivalent tumor response.
Noemi Giannini +18 more
doaj +3 more sources
FLASH Radiotherapy: a Promising Direction in the Fight Against Cancer [PDF]
Вестник рентгенологии и радиологии, 2021 At the present stage of scientific and technological progress, high-dose radiotherapy has become a common way to combat severe cancers. However, this treatment option is limited by normal tissues radiosensitivity.
А. V. Каrtashev +2 more
doaj +2 more sources
Absolute dosimetry for FLASH proton pencil beam scanning radiotherapy [PDF]
Scientific Reports, 2023 A paradigm shift is occurring in clinical oncology exploiting the recent discovery that short pulses of ultra-high dose rate (UHDR) radiation—FLASH radiotherapy—can significantly spare healthy tissues whilst still being at least as effective in curing ...
Ana Lourenço +14 more
doaj +3 more sources
Efficacy of Radiotherapy FLASH-RT: From Treating Lung Cancer to Preventing Pulmonary Fibrosis
Dose-ResponseFLASH radiotherapy (FLASH-RT) is a radiotherapy technique that achieves ultra-high dose rates in a fraction of a second. Based on data from experimental animal models, FLASH-RT appears to protect a number of normal tissues from radiation-induced damage ...
Tianyu Yang +4 more
doaj +2 more sources
FLASH Radiotherapy: Mechanisms of Biological Effects and the Therapeutic Potential in Cancer
BiomoleculesRadiotherapy is an important treatment for many unresectable advanced malignant tumors, and radiotherapy-associated inflammatory reactions to radiation and other toxic side effects are significant reasons which reduce the quality of life and survival of ...
Ouying Yan +3 more
doaj +2 more sources
The FLASH effect—an evaluation of preclinical studies of ultra-high dose rate radiotherapy
Frontiers in OncologyFLASH radiotherapy (FLASH-RT) is a novel radiotherapy approach based on the use of ultra-high dose radiation to treat malignant cells. Although tumours can be reduced or eradicated using radiotherapy, toxicities induced by radiation can compromise ...
Josie May McGarrigle +4 more
doaj +2 more sources
Expert consensus on clinical trial design guidelines for FLASH radiotherapy. [PDF]
Precis Radiat Oncol• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Luo H +9 more
europepmc +2 more sources