Results 31 to 40 of about 422,772 (173)

Long-term anti-tumor effects following both conventional radiotherapy and FLASH in fully immunocompetent animals with glioblastoma

Scientific Reports, 2022
Radiotherapy can induce an immunological response. One limiting factor is side effects on normal tissue. Using FLASH radiotherapy, side effects could possibly be reduced.
Emma Liljedahl, Elise Konradsson, Emma Gustafsson, Karolina Förnvik Jonsson, Jill K. Olofsson, Crister Ceberg, Henrietta Nittby Redebrandt   +6 more
doaj   +1 more source

Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?

Frontiers in Oncology, 2020
Radiotherapy is a cornerstone of both curative and palliative cancer care. However, radiotherapy is severely limited by radiation-induced toxicities. If these toxicities could be reduced, a greater dose of radiation could be given therefore facilitating ...
Joseph D. Wilson, Ester M. Hammond, Geoff S. Higgins, Kristoffer Petersson, Kristoffer Petersson   +4 more
doaj   +1 more source

FLASH radiotherapy

, 2023
Bakalářská práce "FLASH radioterapie " se zaměřuje na popis, seznámení a vývoj nové, slibně se vyvíjející metodě radioterapie. Teoretická část práce je věnována charakteristice a historii radioterapie její rozdělení a druhům radioterapie.
Kysela, Kryštof
core   +1 more source

FLASH Irradiation Spares Lung Progenitor Cells and Limits the Incidence of Radio-induced Senescence

, 2020
PURPOSE: One of the main limitations to anticancer radiotherapy lies in irreversible damage to healthy tissues located within the radiation field.
Heinrich, Sophie, Leboucher, Sophie, Curras-Alonso, Sandra, Bohec, Mylène, Beddok, Arnaud, Karakurt, Hamza Umut, Verrelle, Pierre, Fouillade, Charles, Vooijs, Marc, Dutreix, Marie, Quelennec, Eddy, Bonnet-Boissinot, Sarah, Favaudon, Vincent, Baulande, Sylvain, Londoño-Vallejo, Arturo, Giuranno, Lorena   +15 more
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Architecture, flexibility and performance of a special electron linac dedicated to Flash radiotherapy research: electronFlash with a triode gun of the centro pisano flash radiotherapy (CPFR)

Frontiers in Physics, 2023
The FLASH effect is a radiobiological phenomenon that has garnered considerable interest in the clinical field. Pre-clinical experimental studies have highlighted its potential to reduce side effects on healthy tissues while maintaining isoeffectiveness ...
F. Di Martino, F. Di Martino, F. Di Martino, D. Del Sarto, D. Del Sarto, D. Del Sarto, G. Bass, S. Capaccioli, S. Capaccioli, M. Celentano, M. Celentano, D. Coves, A. Douralis, M. Marinelli, M. Marrale, M. Marrale, M. Marrale, L. Masturzo, L. Masturzo, G. Milluzzo, M. Montefiori, M. Montefiori, F. Paiar, F. Paiar, J. H. Pensavalle, J. H. Pensavalle, L. Raffaele, F. Romano, A. Subiel, E. Touzain, G. Verona Rinati, G. Felici   +31 more
doaj   +1 more source

FLASH radiotherapy with photon beams

, 2021
Ultra-high-dose rate “FLASH” radiotherapy (FLASH-RT) has been shown to drastically reduce normal tissue toxicities while being as efficacious as conventional dose rate radiotherapy to treat tumors. A large number of preclinical studies describing this so-
Pierre Montay-Gruel (10218812), Jean A Laissue (20261685), Magdalena Bazalova-Carter (6619208), Stéphanie Corde (20261682)   +3 more
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FLASH radiotherapy and the associated dosimetric challenges

, 2023
At Lund University and Skåne University Hospital in Lund, Sweden, we have, as the first clinic, modified a clinical Elekta Precise linear accelerator for convertible delivery of ultrahigh dose rate (FLASH) irradiation.
Ceberg, S., Ceberg, C., Konradsson, E., Kügele, M., Kadhim, M., Mannerberg, A., Edvardsson, A., Bäck, S. Å.J., Blomstedt, M., Petersson, K., Jamtheim Gustafsson, C.   +10 more
core   +2 more sources

Combining FLASH and spatially fractionated radiation therapy: the best of both worlds.

, 2022
FLASH radiotherapy (FLASH-RT) and spatially fractionated radiation therapy (SFRT) are two new therapeutical strategies that use non-standard dose delivery methods to reduce normal tissue toxicity and increase the therapeutic index.
Prezado, Yolanda, Fernandez Palomo, Cristian Gabriel, Fazzari, Jennifer Michelina, Djonov, Valentin Georgiev, Schneider, Tim, Iturri, Lorea, Martin, Olga Alexeevna, Bertho, Annaïg, Trappetti, Verdiana   +8 more
core   +1 more source

FLASH radiotherapy: an emerging approach in radiation therapy [PDF]

, 2022
FLASH radiotherapy (RT) is a technique involving the delivery of ultra-high dose rate radiation to the target. FLASH-RT has been shown to reduce radiation-induced toxicity in healthy tissues without compromising the anti-cancer effects of treatment ...
Misiarz, Agnieszka; Centre of High Technology HITEC, Swierk, Otwock, Poland, Otwock, Poland, Pracz, Jacek; Centre of High Technology HITEC, Swierk, Otwock, Poland, Otwock, Poland, Kruszyna-Mochalska, Marta; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland; Medical Physics Department, The Greater Poland Cancer Centre, Poznan, Poland, Milecki, Piotr; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland; Department of Radiotherapy I, The Greater Poland Cancer Centre, Poznan, Poland, Matuszak, Natalia; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland; Radiobiology Lab. Medical Physics Department, The Greater Poland Cancer Centre, Poznan, Poland, Suchorska, Wiktoria Maria; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland; Radiobiology Lab. Medical Physics Department, The Greater Poland Cancer Centre, Poznan, Poland, Malicki, Julian; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland; Department of Medical Physics, Greater Poland Cancer Centre, Poznan, Poland, Matuszak, Natalia, Julian Malicki, Misiarz, Agnieszka, Wiktoria Maria Suchorska, Jacek Pracz, Natalia Matuszak, Pracz, Jacek, Piotr Milecki, Suchorska, Wiktoria Maria, Marta Kruszyna-Mochalska, Milecki, Piotr, Kruszyna-Mochalska, Marta, Agnieszka Misiarz, Malicki, Julian   +20 more
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Flash radiotherapy - window of opportunity at an embryonic stage [PDF]

, 2023
No tumor group can be irresponsive to chemotherapy, especially radiotherapy, when applied in sufficient doses. However, in most cases, it is not possible to give effective doses that can destroy the tumor due to side effects and damage that may occur in ...
Uslu, Gonca Hanedan, Yavuz, Aydın
core   +1 more source