Results 61 to 70 of about 38,156 (252)

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Femtosecond dynamics of flavoproteins: Charge separation and recombination in riboflavine (vitamin B_2)-binding protein and in glucose oxidase enzyme [PDF]

, 2001
Flavoproteins can function as hydrophobic sites for vitamin B_2 (riboflavin) or, in other structures, with cofactors for catalytic reactions such as glucose oxidation.
Zewail, Ahmed H., Zhong, Dongping
core  

Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]

, 2019
Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing, Tian, Li, Wilson, Alexander E, Wu, Sheng   +3 more
core   +1 more source

FLAVIN-ADENINE DINUCLEOTIDE-SYNTHESIZING ENZYME IN EREMOTHECIUM ASHBYII

THE JOURNAL OF VITAMINOLOGY, 1961
The existence of an enzyme catalyzing FAD synthesis from FMN and ATP was proved in mycelium of Er. ashbyii. The enzyme requires Mg2+ or Mn2+ for its full activity. The optimum pH is 8.0. When riboflavin is added to the reaction mixture in place of FMN, FAD synthesis occurs also, but not so much as in the case of FMN.
T, KOBAYASHI, T, SUZUE
openaire   +3 more sources

Improving the Skin‐Conformability of Wearable Continuous Glucose Monitors With Synthetic Hydrogel Electrodes

Advanced Science, EarlyView.
A synthetic hydrogel electrode for skin‐conformable enzymatic biosensing is presented, featuring a stretchable, tape‐shaped continuous glucose monitor for non‐invasive diabetes management. ABSTRACT Synthetic bioelectronics is rapidly advancing, propelled by breakthroughs in synthetic biology and bioelectronics.
Binbin Cui, Shilei Dai, Ivo Pang, Dingyao Liu, Xinran Zhang, Jing Bai, Xinyu Tian, Shiming Zhang   +7 more
wiley   +1 more source

Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions

Scientific Reports, 2017
Multiphoton excitation microscopy (MPM) is regarded as an effective tool that enables the visualization of deep regions within living tissues and organs, with little damage.
Takahiro Matsui, Hiroki Mizuno, Takao Sudo, Junichi Kikuta, Naotsugu Haraguchi, Jun-ichiro Ikeda, Tsunekazu Mizushima, Hirofumi Yamamoto, Eiichi Morii, Masaki Mori, Masaru Ishii   +10 more
doaj   +1 more source

FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR) [PDF]

, 2014
Adenosylcobalamin, the coenzyme form of vitamin B12, is one Nature's most complex coenzyme whose de novo biogenesis proceeds along either an anaerobic or aerobic metabolic pathway. The aerobic synthesis involves reduction of the centrally chelated cobalt
Alan Scott, Andrew D. Lawrence, Banerjee, Blanche, Cheng, Cheung, Christopher M. Johnson, Dalhus, Daragan, Debussche, Delaglio, Delaglio, Emsley, Evans, Fogh, Fonseca, Johnson, Kim, Lawrence, Leslie, Lexa, Mark J. Howard, Martin J. Warren, Mera, Michael A. Geeves, Michelle L. Rowe, Monera, Murshudov, Pace, Parsons, Piotto, Rashid, Richard W. Pickersgill, Samantha L. Taylor, Sampson, States, Stephen E. J. Rigby, Stich, Stich, Vagin, van den Heuvel, Vranken, Warren, Webb, Wishart, Wittung-Stafshede   +45 more
core   +3 more sources

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

The in-silico study of the structural changes in the Arthrobacter globiformis choline oxidase induced by high temperature

Journal of Genetic Engineering and Biotechnology
Background: Choline oxidase, a flavoprotein, is an enzyme that catalyzes the reaction which converts choline into glycine betaine. Choline oxidase started its journey way back in 1933.
Sonia Kaushik, Rashmi Rameshwari, Shilpa S. Chapadgaonkar   +2 more
doaj   +1 more source