Results 1 to 10 of about 45,388 (244)

A biomimetic redox flow battery based on flavin mononucleotide [PDF]

Nature Communications, 2016
Redox flow batteries using organic active materials are highly sought after because of their potential to satisfy low cost and sustainability requirements. Here, the authors report a biomimetic flow battery based on flavin mononucleotide and a hydrotrope
Akihiro Orita, Michael G. Verde, Masanori Sakai, Ying Shirley Meng   +3 more
exaly   +10 more sources

Affinity-Based Profiling of the Flavin Mononucleotide Riboswitch. [PDF]

J Am Chem Soc, 2022
Riboswitches are structural RNA elements that control gene expression. These naturally occurring RNA sensors are of continued interest as antibiotic targets, molecular sensors, and functional elements of synthetic circuits. Here, we describe affinity-based profiling of the flavin mononucleotide (FMN) riboswitch to characterize ligand binding and ...
Crielaard S, Maassen R, Vosman T, Rempkens I, Velema WA.   +4 more
europepmc   +6 more sources

Flavin Mononucleotide as a Biomarker of Organ Quality—A Pilot Study [PDF]

Transplantation Direct, 2020
Background. Flavin mononucleotide (FMN), released from damaged mitochondrial complex I during hypothermic liver perfusion, has been shown to be predictive of 90-day graft loss. Normothermic machine perfusion (NMP) and normothermic regional perfusion (NRP)
Lu Wang, MRCS, Emily Thompson, MRCS, Lucy Bates, BSc, Thomas L. Pither, BSc, Sarah A. Hosgood, PhD, Michael L. Nicholson, DSc, Christopher J.E. Watson, MD, Colin Wilson, PhD, Andrew J. Fisher, PhD, Simi Ali, PhD, John H. Dark, FRCS   +10 more
doaj   +3 more sources

Photodynamic therapy of melanoma by blue-light photoactivation of flavin mononucleotide [PDF]

Scientific Reports, 2019
Melanoma is one of the most aggressive and lethal form of cancer. Photodynamic therapy (PDT) is a clinically approved technique for cancer treatment, including non-melanoma skin cancer.
R. A. Akasov, N. V. Sholina, D. A. Khochenkov, A. V. Alova, P. V. Gorelkin, A. S. Erofeev, A. N. Generalova, E. V. Khaydukov   +7 more
doaj   +3 more sources

Flavin Biosynthesis Enhances Extracellular Electron Transfer in Bioengineered Escherichia coli [PDF]

Advanced Science
Advancements in bioengineering have unlocked new microbial electrochemical applications in energy, sensing, remediation, and synthesis. Key to realizing these technologies is the engineering of conduits in metabolically versatile microbes like ...
Mohammed Mouhib, Melania Reggente, Hanxuan Wang, Charlotte Roullier, Ardemis A. Boghossian   +4 more
doaj   +3 more sources

Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. [PDF]

ACS Chem Biol, 2018
The flavin mononucleotide (FMN) riboswitch is an emerging target for the development of novel RNA-targeting antibiotics. We previously discovered an FMN derivative, 5FDQD, that protects mice against diarrhea-causing Clostridium difficile bacteria. Here, we present the structure-based drug design strategy that led to the discovery of this fluoro-phenyl ...
Vicens Q, Mondragón E, Reyes FE, Coish P, Aristoff P, Berman J, Kaur H, Kells KW, Wickens P, Wilson J, Gadwood RC, Schostarez HJ, Suto RK, Blount KF, Batey RT.   +14 more
europepmc   +5 more sources

Lactobacillus plantarum Generate Electricity through Flavin Mononucleotide-Mediated Extracellular Electron Transfer to Upregulate Epithelial Type I Collagen Expression and Thereby Promote Microbial Adhesion to Intestine [PDF]

Biomedicines, 2023
The mechanism behind how flavin mononucleotide (FMN)-producing bacteria attach to a host intestine remains unclear. In order to address this issue, this study isolated the Gram-positive bacteria Lactobacillus plantarum from Mongolian fermented Airag ...
Binderiya Ganzorig, Enkhbat Zayabaatar, Minh Tan Pham, Shinta Marito, Chun-Ming Huang, Yu-Hsiang Lee   +5 more
doaj   +2 more sources

NfoR: Chromate Reductase or Flavin Mononucleotide Reductase? [PDF]

Appl Environ Microbiol, 2020
Chromate is a toxic by-product of multiple industrial processes. Chromate reduction is an important biological activity that ameliorates Cr(VI) toxicity. Numerous researchers have identified chromate reductase activity by observing chromate reduction.
O'Neill AG, Beaupre BA, Zheng Y, Liu D, Moran GR.   +4 more
europepmc   +4 more sources

The Activation of Cytochrome P450 2C9 Is Facilitated by the Coenzyme Forms of Vitamin B2 [PDF]

Molecules
The activity of cytochrome P450 enzymes decreases in older adults, which can lead to toxic effects from polypharmacy. Cytochromes P450 are the most significant enzymes involved in the metabolism of foreign compounds, including pharmaceutical substances ...
Polina I. Koroleva, Alexey V. Kuzikov, Andrei A. Gilep, Sergey V. Ivanov, Alexander I. Archakov, Victoria V. Shumyantseva   +5 more
doaj   +2 more sources

Quantifying Flavin mononucleotide: an internationally validated methodological approach for enhanced decision making in organ transplantation. [PDF]

EBioMedicine
BACKGROUND: Increasing donor risk, particularly in liver transplantation, where organs are often marginal, has made dynamic organ preservation techniques and viability assessment essential to safely improve organ quality and increase utilisation. However, existing viability parameters are based on routine clinical assessment in patients with acute ...
Sun K, Jiao C, Panconesi R, Satish S, Karakaya OF, De Goeij FHC, Diwan T, Ali K, Cadinu LA, Cazzaniga B, Liu Q, Miyazaki Y, Pita A, Khalil M, Kim J, Hussein A, Müller PC, Aucejo F, Kwon DHC, Fernandes E, Esfeh JM, Cywinski J, Fujiki M, Sun L, Pinna A, Dutkowski P, Wehrle CJ, Fairchild RL, Meierhofer D, De Jonge J, Miller C, Hashimoto K, Schlegel A.   +32 more
europepmc   +4 more sources