Results 51 to 60 of about 7,181 (257)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta +17 more
wiley +1 more source
Exploring the mechnisms of molecular recognition by flavins
, 2005 The design and development of chemical models for enzymes depends on the fundamental principles observed in biological systems. Molecular recognition of flavins by various receptors has attracted attention due to their applications as chemical models for
Babu, Cherukuri Raghavendra +2 more
core +1 more source
Ultrafast excited-state deactivation of flavins bound to dodecin
, 2021 Dodecins, a group of flavin-binding proteins with a dodecameric quaternary structure, are able to incorporate two flavins within each of their six identical binding pockets building an aromatic tetrade with two tryptophan residues.
Staudt, Heike +3 more
core +1 more source
SURFACE-ENHANCED RAMAN SPECTROSCOPY OF FLAVINS AND FLAVOPROTEINS
, 1986 Address of Lee and Morris: Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.Author Institution:The N(3) anions of flavins are shown to be responsible for surface enhancement of Raman spectra on silver colloids.
Morris, Michael D., Lee, Nam-Soo
core
Advanced Physics Research, EarlyView.A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley +1 more source
FLAVIN-HYPOXANTHINE DINUCLEOTIDE
THE JOURNAL OF VITAMINOLOGY, 1957 1. FHD was synthesized from FAD by deamination with nitrous acid and the product was first isolated as barium salt. The yield and purity were, however, unsatisfactory by this method. Therefore, the product was extracted with cresol, followed by transfer in aqueous phase, and by subjecting to column chromatography, FHD was obtained in high purity in ...
openaire +3 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp +6 more
wiley +1 more source
, 2012 Excited flavin molecules can photocatalyze reactions, leading to the accumulation of free energy in the products, and the data accumulated through biochemical experiments and by modeling prebiological processes suggest that flavins were available in the ...
Mikhail Kritsky +3 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf +6 more
wiley +1 more source