Results 61 to 70 of about 7,181 (257)
Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
A Molecular Mechanics Model for Flavins
, 2019 International audienceFlavin containing molecules form a group of important cofactors that assist a wide range of enzymatic reactions. Flavins use the redox‐active isoalloxazine system, which is capable of one‐ and two‐electron transfer reactions and can
Aleksandrov, Alexey, Alexey Aleksandrov
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Synthesis and electronic properties of π-extended flavins [PDF]
, 2015 Flavin derivatives with an extended pi-conjugation were synthesized in moderate to good yields from aryl bromides via a Buchwald-Hartwig palladium catalyzed amination protocol, followed by condensation of the corresponding aromatic amines with violuric ...
Leitl, Markus J. +7 more
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Biotechnology and Bioengineering, EarlyView.ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian +4 more
wiley +1 more source
, 2013 In this work we study the incorporation into dipalmitoylphosphatidylcholine (DPPC) small unilamellar vesicle (SUV), of three indols: Trp, indol-3 acetamide and N-acetyl tryptophan ethyl ester (NATE), and of three flavins: riboflavin (RF), lumiflavin (LF),
A. M. Edwards +5 more
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Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
BMEMat, EarlyView.This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
, 2016 Flavins, comprising flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD), and riboflavin (RF, vitamin B2), play important roles in numerous redox reactions such as those taking place in the electron-transfer chains of mitochondria in all ...
Hun Hee Park (2360491) +12 more
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High‐Energy‐Density Redox Flow Batteries: Mechanisms, Design Strategies, and Recent Progress
Chemistry – A European Journal, EarlyView.ABSTRACT The inherent intermittency of energy sources such as solar and wind power hinders the transition to renewable energy, necessitating advanced energy storage solutions. Enhancing energy density is crucial for lowering system costs and enabling large‐scale deployment.
Xiaolian Zhao +8 more
wiley +1 more source
, 2010 The Mtr respiratory pathway of Shewanella oneidensis strain MR-1 is required to effectively respire both soluble and insoluble forms of oxidized iron.
Dan Coursolle +3 more
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