Results 31 to 40 of about 28,583 (169)

Flying under the radar – impact and factors influencing asymptomatic DENV infections

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The clinical outcome of DENV and other Flaviviruses infections represents a spectrum of severity that ranges from mild manifestations to severe disease, which can ultimately lead to death.
Paulo Henriques   +7 more
doaj   +1 more source

Case report: Regression of Glioblastoma after flavivirus infection

open access: yesFrontiers in Medicine, 2023
Glioblastoma is the most frequent and aggressive primary brain cancer. In preclinical studies, Zika virus, a flavivirus that triggers the death of glioblastoma stem-like cells. However, the flavivirus oncolytic activity has not been demonstrated in human patients.
Patricia P. Garcez   +24 more
openaire   +3 more sources

Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines

open access: yesFrontiers in Immunology, 2022
The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan   +15 more
doaj   +1 more source

Recent Advances in the Development of Virus-Like Particle-Based Flavivirus Vaccines

open access: yesVaccines, 2020
Flaviviruses include several medically important viruses, such as Zika virus (ZIKV), Dengue virus (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV).
Naru Zhang   +3 more
doaj   +1 more source

ZIKV Infection and miRNA Network in Pathogenesis and Immune Response

open access: yesViruses, 2021
Over the years, viral infections have caused severe illness in humans. Zika Virus (ZIKV) is a flavivirus transmitted by mosquito vectors that leads to notable neurological impairment, whose most dramatic impact is the Congenital ZIKV Syndrome (CZS). ZIKV
Carolina Manganeli Polonio   +1 more
doaj   +1 more source

Protective to a T: The Role of T Cells during Zika Virus Infection

open access: yesCells, 2019
CD4 and CD8 T cells are an important part of the host’s capacity to defend itself against viral infections. During flavivirus infections, T cells have been implicated in both protective and pathogenic responses.
Ryan D. Pardy, Martin J. Richer
doaj   +1 more source

A Recombinant Zika Virus Envelope Protein with Mutations in the Conserved Fusion Loop Leads to Reduced Antibody Cross-Reactivity upon Vaccination

open access: yesVaccines, 2020
Zika virus (ZIKV) is a zoonotic, human pathogenic, and mosquito-borne flavivirus. Its distribution is rapidly growing worldwide. Several attempts to develop vaccines for ZIKV are currently ongoing.
Beatrice Sarah Berneck   +4 more
doaj   +1 more source

Anti-flavivirus Properties of Lipid-Lowering Drugs

open access: yesFrontiers in Physiology, 2021
Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human pathogens, an effective vaccine or antiviral treatment against them is not available. Hence, the search for new strategies to control flavivirus infections is essential.
Carlos Noe Farfan-Morales   +8 more
doaj   +1 more source

Zika Virus: A New Chapter in the History of Medicine

open access: yesActa Médica Portuguesa, 2016
Keywords: Aedes; Arboviruses; Flavivirus; Flaviviridae Infections.
Carlos Brito
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

open access: yesAdvanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras   +6 more
wiley   +1 more source

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