Results 31 to 40 of about 26,788 (261)

Cross-Reactive Immunity among Five Medically Important Mosquito-Borne Flaviviruses Related to Human Diseases

open access: yesViruses, 2022
Flaviviruses cause a spectrum of potentially severe diseases. Most flaviviruses are transmitted by mosquitoes or ticks and are widely distributed all over the world.
Baohua Hou, Hui Chen, Na Gao, J. An
semanticscholar   +1 more source

Application of DNA Replicons in Gene Therapy and Vaccine Development

open access: yesPharmaceutics, 2023
DNA-based gene therapy and vaccine development has received plenty of attention lately. DNA replicons based on self-replicating RNA viruses such as alphaviruses and flaviviruses have been of particular interest due to the amplification of RNA transcripts
Kenneth Lundstrom
doaj   +1 more source

Replication is the key barrier during the dual-host adaptation of mosquito-borne flaviviruses

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance Most viruses have a relatively narrow host range. In contrast, vector-borne flaviviruses, such as dengue virus and Zika virus, maintain their transmission cycle between arthropods and vertebrates, belonging to different phyla.
Yanan Zhang   +9 more
semanticscholar   +1 more source

Domestic Dogs as Sentinels for West Nile Virus but not Aedes-borne Flaviviruses, Mexico

open access: yesEmerging Infectious Diseases, 2022
We tested 294 domestic pet dogs in Mexico for neutralizing antibodies for mosquito-borne flaviviruses. We found high (42.6%) exposure to West Nile virus in Reynosa (northern Mexico) and low (1.2%) exposure in Tuxtla Gutierrez (southern Mexico) but very ...
Edward Davila   +24 more
semanticscholar   +1 more source

Flaviviruses as agents of childhood central nervous system infections in Brazil

open access: yesNew Microbes and New Infections, 2019
Flaviviruses are agents of a major emerging human public health issue, and members of the Flavivirus genus have been associated with central nervous system (CNS) infections.
P.E. Silva Marinho, E.G. Kroon
doaj   +3 more sources

From Capsids to Complexes: Expanding the Role of TRIM5α in the Restriction of Divergent RNA Viruses and Elements

open access: yesViruses, 2021
An evolutionary arms race has been ongoing between retroviruses and their primate hosts for millions of years. Within the last century, a zoonotic transmission introduced the Human Immunodeficiency Virus (HIV-1), a retrovirus, to the human population ...
Kevin M. Rose   +6 more
doaj   +1 more source

Adenovirus vector-based vaccines as forefront approaches in fighting the battle against flaviviruses

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Flaviviruses are arthropod-borne viruses (arboviruses) that have been recently considered among the significant public health problems in defined geographical regions. In this line, there have been vaccines approved for some flaviviruses including dengue
M. Shoushtari   +5 more
semanticscholar   +1 more source

Acute neurologic emerging flaviviruses

open access: yesTherapeutic Advances in Infectious Disease, 2022
The COVID-19 pandemic has shed light on the challenges we face as a global society in preventing and containing emerging and re-emerging pathogens. Multiple intersecting factors, including environmental changes, host immunological factors, and pathogen ...
Marissa Caldwell, A. Boruah, K. Thakur
semanticscholar   +1 more source

Quercetin Inhibits Hsp70 Blocking of Bovine Viral Diarrhea Virus Infection and Replication in the Early Stage of Virus Infection

open access: yesViruses, 2022
Bovine viral diarrhea virus (BVDV), a positive-strand RNA virus of the genus Pestivirus in the Flaviviridae family, is the causative agent of viral diarrheal disease in bovine.
Nannan Chen   +10 more
doaj   +1 more source

Cross-Reactive Immunity Among Flaviviruses

open access: yesFrontiers in Immunology, 2020
Flaviviruses consist of significant human pathogens responsible for hundreds of millions of infections each year. Their antigenic relationships generate immune responses that are cross-reactive to multiple flaviviruses and their widespread and ...
Abhay P. S. Rathore, A. S. St. John
semanticscholar   +1 more source

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