Results 131 to 140 of about 28,760 (248)

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +1 more source

First Report on the Phytochemical and Pharmacological Properties of Hedysarum yilmazunalii

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Hedysarum yilmazunalii was collected from Erzincan, Türkiye. The leaf, stem, and root parts were then used for methanolic extraction. The extracts were analyzed for their phytochemical composition by LC–MS/MS and tested for antioxidant, enzyme inhibitory, and antiproliferative activities.
Etem Osma, Tuğçe Varol, Samed Şimşek, Sevgi Altın, Mustafa Abdullah Yılmaz, Ali Aydın, Müjgan Elveren, Ali Kandemir   +7 more
wiley   +1 more source

Comparative Phytochemical and Biological Evaluation of Four Thymus Species From Türkiye for Dermocosmetic Applications

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Four Thymus species from Anatolia are profiled through molecular networking and multi‐target bioassays across skin‐relevant cellular models. Triterpene‐rich extracts inhibit key anti‐aging enzymes and promote wound closure in fibroblast, keratinocyte, and endothelial cells.
Ebru Özdemir Nath, Pierre‐Eric Campos, Audrey Le Cabec, Gül İpek Gündoğan, Diren Ergin, Ahsen Çetin, Sefa Sönmez, Emilie Destandau   +7 more
wiley   +1 more source

Two Prenylated Flavones from the Tree Bark of Artocarpus lanceifolius

, 2006
Two new prenylated flavones, artoindonesianins Z-1 (1) and Z-2 (2), together with two other known prenylated flavones, artobiloxantone (3) and cycloartobiloxanthone (4), had been isolated and identified from the chloroform extract of the tree bark of ...
Lia D Juliawaty, Norio Aimi, Euis H Hakim, Yana M Syah, Sjamsul A Achmad, Hiromitsu Takayama   +5 more
core  

Qualitative Analysis of Chemical Composition Changes Before and After Lactobacillus Fermented Ziziphi Spinosae Semen by LC‐MS and Prediction of Fermentation Mechanism

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
ABSTRACT This study aimed to screen dominant Lactobacillus strains for fermenting Ziziphi Spinosae Semen (ZSS), analyze chemical composition changes before and after fermentation, and speculate on the fermentation mechanism. Liquid fermentation of ZSS was conducted using Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus acidophilus, and ...
Jiafu Wan, Yunda Wang, Xiaoxue Yang, Qingmei Guo   +3 more
wiley   +1 more source

Flavones from some Canary species of Sideritis

, 1978
From species of the genus Sideritis (Labiatae) endemic to the Canary Islands, several new diterpenes (1, 2) were previously obtained together with the coumarin siderin (3).
Hernández, Melchor G., Fraga, Braulio M., González, Antonio G., Larruga, Francisca, Ravelo, Ángel G., Luis, J. G.   +5 more
core  

Exploring the Multitarget Pharmacological Potential of Halogeton sativus Secondary Metabolites: An Integrated Experimental and Computational Approach

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Halogeton sativus is investigated through phytochemical isolation, biological evaluation, molecular dicking, molecular dynamics simulation, and ADMET prediction. The identified metabolites exhibit promising antioxidant, anti‐inflammatory, antimicrobial, and antidiabetic activities, while computational analyses provide mechanistic insights and favorable
Abd Elbasset Tamersit, Soumia Mouffouk, Chaima Mouffouk, Faizul Azam, Rayan A. Mulla, Najeh Kharbatia, Mariusz Jaremko, Abdul‐Hamid Emwas, Nourhene Hamdaoui, Saoudi Mongi, Sara Mouffouk, Waffa Bouafia, Hamada Haba   +12 more
wiley   +1 more source

Antioxidant Chemistry of Phenolics in Chinese Herbal Medicines: A Holism‐Based Review

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Phenolic antioxidants in CHMs mainly include chalcone, stilbene, flavonoid, xanthone, and Diels–Alder‐type adducts. They undergo direct and indirect pathways to exert antioxidant action. The indirect pathway is transition metal‐chelating, while the direct pathway comprises several redox‐based reactions (e.g., SET and HAT) and RAF reactions.
Xican Li
wiley   +1 more source

Saussurea tridactyla Sch. Bip.-Derived Polysaccharides and Flavones Reduce Oxidative Damage in Ultraviolet B-Irradiated HaCaT Cells via a p38MAPK-Independent Mechanism [Retraction]

Drug Design, Development and Therapy
Guo Y, Sun J, Ye J, Ma W, Yan H, Wang G. Drug Des Devel Ther. 2016;10:389—403. We, the Editors and Publisher of the journal Drug Design, Development and Therapy have retracted the published article.
Guo Y, Sun J, Ye J, Ma W, Yan H, Wang G
doaj  

Classification, Structure–Activity Relationship, and Anti‐Osteoarthritis Mechanism of Natural Flavonoids

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Natural product flavonoids have a multi‐target therapeutic intervention effect on osteoarthritis. They promote autophagy and cartilage synthesis while alleviating oxidative stress, inhibiting inflammation, and inhibiting matrix degradation. By restoring OPG/RANKL balance and regulating bone metabolism, these compounds synergistically delay the ...
Haibin Wang, Shuqi Zheng, Chunlei Hua, Wanze Feng, Zengxia Liu, Yanhong Sun, Minhui Li   +6 more
wiley   +1 more source