Results 101 to 110 of about 41,055 (201)

Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral Candida: Implications for Managing Drug‐Resistant Infections

Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives Antifungal drug resistance poses a major challenge in treating oral Candida infections. This study aimed to evaluate the antifungal activity of Honokiol, alone and combined with Fluconazole, against oral Candida isolates, and to investigate its mechanism of action via ergosterol biosynthesis inhibition and cell wall disruption ...
Maribasappa Karched, Mohammad Irshad, Jawad M. Behbehani   +2 more
wiley   +1 more source

Lipase Gene Expression of Resistant and Sensitive Candida Albicans to Fluconazole Isolated from Patients Suffering from Oral Candidiasis and Vaginal Candidiasis

Medical Laboratory Journal, 2015
Background and Objective: With the development of drug resistance in strains of fungi, there is a considerable resistance of Candida albicans strains to fluconazole. Molecular studies are developing to determine the relationship of such a drug resistance
Nasrollahi Omran, A, Nazemi, A, Kihanian, SH, Aryana , N   +3 more
doaj  

Reduced susceptibility to fluconazole in a cat with histoplasmosis

Journal of Feline Medicine and Surgery Open Reports, 2017
Case summary An 11-year-old neutered male domestic longhair cat was diagnosed with histoplasmosis from fine-needle aspirates of an abdominal lymph node. Lymph node size initially decreased with fluconazole therapy (11.8 mg/kg PO q12h); however, after 13 ...
Janelle S Renschler, Gary D Norsworthy, Rubie A Rakian, Audrey I Rakian, Lawrence J Wheat, Andrew S Hanzlicek   +5 more
doaj   +1 more source

Yersinia enterocolitica in Italy. A case of septicemia and abdominal aortic aneurysm infection [PDF]

, 2018
We report a case of Yersinia enterocolitica septicemia in a 63-year-old patient admitted to the Vascular Surgery Department of Umberto I Hospital (Rome, Italy) for an abdominal aortic aneurysm.
Alessia Bressan, Cecilia Ambrosi, Cecilia Ambrosi, Daniela Scribano, Donatella M. Rodio, Francesco Speziale, Guido Antonelli, Maria Trancassini, Rita Tolli, Valeria Pietropaolo, Wassim Mansour   +10 more
core   +2 more sources

Molecular Identification and Evaluation of Resistance to Antifungal Drugs in Candida Species Isolated From Diaper Rash of Neonates

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Diaper dermatitis, also recognized as diaper rash, is one of the most frequent skin conditions in neonates. Materials and Methods A total of 100 babies participated in the study. Eligibility included neonates aged 5–28 days and full‐time diaper wearers.
Fariba Shirvani, Mahsa Fattahi, Abdollah Karimi, Shahnaz Armin, Seyed Alireza Fahimzad, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaei, Fatemeh Fallah, Alireza Firooz, Shahrzad Tabatabaee, Mitra Radfar, Dorsa Kalani, Hossein Foroozan, Afagh firoozgaeean Galoogah, Pegah Tamimi   +14 more
wiley   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

Journal of Applied Toxicology, Volume 46, Issue 2, Page 682-696, February 2026.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros, Sávia Soraia Santana da Silva, Eduarda Pinto Gagliano, Alícia Natalie Silva dos Santos, Leydianne Leite de Siqueira Patriota, Gustavo Ramos Salles Ferreira, Pollyanna Michelle da Silva, Simone da Paz Leôncio Alves, Julliano Matheus de Lima Maux, Jacinto da Costa Silva Neto, Fernanda Rafaelly Nascimento de Santana, Fabiana Aparecida Cavalcante Silva, Marilene Henning Vainstein, Luana Cassandra Breitenbach Barroso Coelho, Thâmarah de Albuquerque Lima, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva   +16 more
wiley   +1 more source

Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates [PDF]

, 2011
The effectiveness of the potent antifungal drug fluconazole is being compromised by the rise of drug-resistant fungal pathogens. While inhibition of Hsp90 or calcineurin can reverse drug resistance in Candida, such inhibitors also impair the homologous ...
Bittker, Joshua A., Buhrlage, Sara J., Dandapani, Sivaraman, Hartland, Cathy L., Johnston, Stephen, Lindquist, Susan, MacPherson, Lawrence, Morgan, Barbara J., Munoz, Benito, Palmer, Michelle, Schreiber, Stuart L., Vincent, Benjamin, Whitesell, Luke, Youngsaye, Willmen   +13 more
core   +1 more source

18‐FDG PET in the Evaluation of Therapeutic Response of Necrotizing Otitis Externa

The Laryngoscope, Volume 136, Issue 2, Page 961-971, February 2026.
PET performed well in assessing the therapeutic response of NEO, with excellent sensitivity but low specificity of visual analysis. A complementary quantitative analysis was useful to distinguish between satisfactory and insufficient partial responses. ABSTRACT Objective The duration of antibiotic treatment for necrotizing otitis externa (NEO) and the ...
Lucie Lécolier, Philippine Toulemonde, Damien Huglo, Clio Baillet, Pauline Thill, Gauthier Delaby   +5 more
wiley   +1 more source

Understanding adaptation to fluconazole: comparative insights into tolerance and resistance in Saccharomyces cerevisiae and Candida albicans

Frontiers in Cellular and Infection Microbiology
IntroductionAntifungal resistance and tolerance are distinct responses exhibited by fungi when exposed to drugs. While considerable research has focused on azole tolerance in the human pathogen Candida albicans, studies in other fungal species remain ...
Lijun Zheng, Yubo Dong, Jing Wang, Yonghui Jia, Weifang Wang, Yi Xu, Yi Xu, Liangsheng Guo   +7 more
doaj   +1 more source

Creation and assessment of a clinical predictive calculator and mortality associated with Candida krusei bloodstream infections [PDF]

, 2018
Background Candida krusei bloodstream infection (CK BSI) is associated with high mortality, but whether this is due to underlying comorbidities in affected patients or the organism itself is unknown.
Hsueh, Kevin, Kronen, Ryan, Lin, Charlotte, Powderly, William G, Spec, Andrej   +4 more
core   +2 more sources