Results 51 to 60 of about 41,055 (201)

First Report of Ventriculoperitoneal Shunt Infection due to Cyberlindnera fabianii. [PDF]

open access: yes, 2015
Fungal infections in the central nervous system (CNS) are associated with significant morbidity and death. Transient fungemia in immunocompetent patients without any other risk factors for fungemia has been suggested as a possible mechanism that may lead
Baghdadi, Jonathan   +3 more
core   +3 more sources

Drug-Resistant Candida glabrata Infection in Cancer Patients

open access: yesEmerging Infectious Diseases, 2014
Cancer patients are at risk for candidemia, and increasing Candida spp. resistance poses an emerging threat. We determined rates of antifungal drug resistance, identified factors associated with resistance, and investigated the correlation between ...
Dimitrios Farmakiotis   +2 more
doaj   +1 more source

A Zinc Cluster Transcription Factor Contributes to the Intrinsic Fluconazole Resistance of Candida auris

open access: yesmSphere, 2020
The recently emerged pathogenic yeast Candida auris is a major concern for human health, because it is easily transmissible, difficult to eradicate from hospitals, and highly drug resistant. Most C.
Eva-Maria Mayr   +3 more
doaj   +1 more source

Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance

open access: yesMicrobiology Spectrum, 2021
Resistance to fluconazole is one of clinical characteristics most frequently challenging the treatment of invasive Candida auris infections, and is observed among >90% of all characterized clinical isolates. In this work, the native C. auris ERG11 allele
Jeffrey M. Rybak   +5 more
doaj   +1 more source

Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]

open access: yes, 2017
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba   +3 more
core   +1 more source

In vitro biofilms and antifungal susceptibility of dermatophyte and non-dermatophyte moulds involved in foot mycosis [PDF]

open access: yes, 2017
Tinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non-dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms.
Bougnoux, Marie Élisabeth   +5 more
core   +1 more source

Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]

open access: yes, 2017
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew   +6 more
core   +4 more sources

Potent In Vitro Synergism of Fluconazole and Osthole against Fluconazole-Resistant Candida albicans [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2017
ABSTRACT Osthole is a natural coumarin that exhibits wide biological and pharmacological activities such as neuroprotective, osteogenic, immunomodulation, antitumor, and anti-inflammatory effects. In this study, we investigated the antifungal effects of osthole in vitro . A checkerboard microdilution assay
De-Dong, Li   +7 more
openaire   +2 more sources

Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]

open access: yes, 2019
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad   +4 more
core   +1 more source

Successful Treatment of Fluconazole-Resistant Oropharyngeal Candidiasis by a Combination of Fluconazole and Terbinafine [PDF]

open access: yesClinical Diagnostic Laboratory Immunology, 1999
ABSTRACT Increasing incidence of resistance to conventional antifungal therapy has demanded that novel therapies be introduced. Recent in vitro studies have shown that combinations involving azoles and allylamines may be effective in inhibiting fluconazole-resistant fungi.
M A, Ghannoum, B, Elewski
openaire   +2 more sources

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