Results 31 to 40 of about 5,632 (146)

Nitrogen concentration affects amphotericin B and fluconazole tolerance of pathogenic cryptococci [PDF]

open access: yesFEMS Yeast Research, 2020
ABSTRACT Environmental stress often causes phenotypic changes among pathogenic cryptococci, such as altered antifungal susceptibility, changes in capsule and melanin formation, as well as altered levels of the membrane sterol and antifungal target, ergosterol.
Caylin Bosch   +4 more
openaire   +2 more sources

Tolerance to fluconazole in Candida albicans is regulated by temperature and aneuploidy

open access: yesAccess Microbiology, 2021
Candida albicans is a prevalent human fungal pathogen. Azoles are the most widely used antifungal drugs. Drug tolerance in bacteria is well defined and thoroughly studied, but in fungi, the definition of drug tolerance and the mechanism that drive it are not well understood. Here, we found that a large proportion of clinical isolates
FENG YANG, YUANYING JIANG, JUDITH BERMAN
openaire   +1 more source

Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes

open access: yesmBio, 2023
Antifungal drug tolerance is a response distinct from resistance, in which cells grow slowly above the MIC. Here, we found that the majority (69.2%) of 133 Candida albicans clinical isolates, including standard lab strain SC5314, exhibited temperature ...
Feng Yang   +7 more
doaj   +1 more source

Systematic truncations of chromosome 4 and their responses to antifungals in Candida albicans

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Candida albicans is an opportunistic human fungal pathogen responsible for superficial and systemic life-threatening infections. Treating these infections is challenging as many clinical isolates show increased drug resistance to antifungals ...
Wasim Uddin   +3 more
doaj   +1 more source

A High Rate of Recurrent Vulvovaginal Candidiasis and Therapeutic Failure of Azole Derivatives Among Iranian Women

open access: yesFrontiers in Microbiology, 2021
Recurrent vulvovaginal candidiasis (RVVC) is one of the most prevalent fungal infections in humans, especially in developing countries; however, it is underestimated and regarded as an easy-to-treat condition.
Amir Arastehfar   +18 more
doaj   +1 more source

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

open access: yes, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Candida bracarensis: Evaluation of Virulence Factors and its Tolerance to Amphotericin B and Fluconazole [PDF]

open access: yesMycopathologia, 2015
Candida bracarensis is an uncommon Candida species found during an epidemiological study of candidiasis performed in Braga, Portugal. Initially, it was identified as C. glabrata, but recently detailed analyses pointed out their differences. So, little information is still available about C. bracarensis virulence factors and antifungal susceptibilities.
Moreira, A.   +5 more
openaire   +3 more sources

Additivity interactions between fluconazole and citrus essential oils to Aspergillus fumigatus

open access: yesJournal of Pre-Clinical and Clinical Research, 2021
Introduction Aspergillus fumigatus is the most common pathogen causing allergic bronchopulmonary mycosis. The pathogenic capacity of Aspergillus fumigatus is related to its thermal tolerance and the small size of the ...
Paula Wróblewska-Łuczka   +1 more
doaj   +1 more source

Candida albicans  Genotyping and Relationship of Virulence Factors with Fluconazole Tolerance in Infected Pediatric Patients

open access: yesInfection and Drug Resistance, 2022
Ghada El-Saeed Mashaly,1 Mayada Sabry Zeid2 1Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 2Infectious Diseases and Malnutrition, Pediatrics Department, Faculty of Medicine, Mansoura University,
Mashaly GE, Zeid MS
doaj  

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