Results 41 to 50 of about 605,588 (181)

Candida bracarensis: Evaluation of Virulence Factors and its Tolerance to Amphotericin B and Fluconazole [PDF]

Mycopathologia, 2015
Candida bracarensis is an uncommon Candida species found during an epidemiological study of candidiasis performed in Braga, Portugal. Initially, it was identified as C. glabrata, but recently detailed analyses pointed out their differences. So, little information is still available about C. bracarensis virulence factors and antifungal susceptibilities.
Moreira, A., Silva, Sónia Carina, Botelho, C. M., Sampaio, Paula, Pais, Célia, Henriques, Mariana   +5 more
openaire   +3 more sources

AMBITION-cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa : study protocol for a randomized controlled trial [PDF]

, 2015
Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine, and difficulties administering 14 days of amphotericin B are key ...
Leeme, Tshepo, Síle F. Molloy, Changalucha, John M., Molefi, Mooketsi, Molloy, Síle F, Meintjes, Graeme, Molloy, Síle F., Goldberg, Drew W, John R. Perfect, Drew W. Goldberg, Kalluvya, Samuel, Cainelli, Francesca, Letang, Emili, Ndhlovu, Chiratidzo E, Perfect, John R, Ndhlovu, Chiratidzo E., Bisson, Gregory P., Miriam Haverkamp, Burton, Rosie, Rosie Burton, Tariro Makadzange, Harrison, Thomas S, Francesca Cainelli, Hope, William, Haverkamp, Miriam, Chiratidzo E. Ndhlovu, Harrison, Thomas S., Jarvis, Joseph N., Chofle, Awilly A, William Hope, Jarvis, Joseph N, Changalucha, John M, Fenner, Lukas, Perfect, John R., Makadzange, Tariro, Joseph N. Jarvis, Tshepo Leeme, Mooketsi Molefi, Nametso Lekwape, Lekwape, Nametso, John M. Changalucha, Emili Letang, Goldberg, Drew W., Lukas Fenner, Bisson, Gregory P, Awilly A. Chofle, Samuel Kalluvya, Thomas S. Harrison, Graeme Meintjes, Chofle, Awilly A., Gregory P. Bisson   +50 more
core   +2 more sources

The assessment of therapeutic response of oropharyngeal and oesophageal candidiasis in AIDS using a new scoring system: studies with D0870. [PDF]

, 1999
We developed and compared five scoring systems designed to quantitate therapeutic response in cases of oropharyngeal candidiasis. We utilized prospectively collected data on 114 patients treated with several doses of the azole D0870.
Williams, Keith, Percy, Meryl, Atkinson, Gill, Denning, David W., Hollis, Sally, Hood, Stephen V.   +5 more
core   +4 more sources

Deletion of the Candida albicans TLO gene family results in alterations in membrane sterol composition and fluconazole tolerance. [PDF]

PLoS One
Development of resistance and tolerance to antifungal drugs in Candida albicans can compromise treatment of infections caused by this pathogenic yeast species. The uniquely expanded C. albicans TLO gene family is comprised of 14 paralogous genes which encode Med2, a subunit of the multiprotein Mediator complex which is involved in the global control of
O'Connor-Moneley J, Fletcher J, Bean C, Parker J, Kelly SL, Moran GP, Sullivan DJ.   +6 more
europepmc   +6 more sources

Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]

, 2013
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Wissing, Heimo, Nocea, Gonzalo, Krobot, Karl J., Kaskel, Peter, Ballus, Jose, Bingold, Tobias Michael, Kumar, Ritesh N., Mavros, Panagiotis   +7 more
core   +1 more source

Activity Based Tolerance Allocation (ABTA) – Driving tolerance synthesis by evaluating its global cost [PDF]

, 2009
This paper deals with tolerance allocation driven by an activity based approach. Its main objective is to rationally give a good indicator of the relevance of tolerances values fixed by designers.
MARTIN, Patrick, SIADAT, Ali, DANTAN, Jean-Yves, ETIENNE, Alain   +3 more
core   +1 more source

Candida albicans  Genotyping and Relationship of Virulence Factors with Fluconazole Tolerance in Infected Pediatric Patients

Infection and Drug Resistance, 2022
Ghada El-Saeed Mashaly,1 Mayada Sabry Zeid2 1Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 2Infectious Diseases and Malnutrition, Pediatrics Department, Faculty of Medicine, Mansoura University,
Mashaly GE, Zeid MS
doaj  

Adherence of Candida albicans to Silicone Induces Immediate Enhanced Tolerance to Fluconazole [PDF]

Antimicrobial Agents and Chemotherapy, 2004
ABSTRACT Wild-type and efflux pump-deficient cells of Candida albicans adhering to silicone were compared with planktonic cells by flow cytometry for their relative resistance to fluconazole (FCZ). Flow cytometry data on cells carrying a fusion of green fluorescent protein to efflux pump promoters ...
Carolina, Mateus, Sidney A, Crow, Donald G, Ahearn   +2 more
openaire   +2 more sources

Cost effectiveness of cryptococcal antigen screening as a strategy to prevent HIV-associated cryptococcal meningitis in South Africa. [PDF]

, 2013
OBJECTIVES: Cryptococcal meningitis (CM)-related mortality may be prevented by screening patients for sub-clinical cryptococcal antigenaemia (CRAG) at antiretroviral-therapy (ART) initiation and pre-emptively treating those testing positive.
Thomas S Harrison, Wood, R, Meintjes, Graeme, Joseph N. Jarvis, Joseph N. Jarvis (435279), Harrison Thomas S., Lawn, Stephen D, Cleary, Susan, Robin Wood, Joseph N Jarvis, Stephen D Lawn, Jarvis, JN, Jarvis Joseph N., Meintjes Graeme, Thomas S. Harrison (222993), Graeme Meintjes (221054), Stephen D. Lawn (116037), Robin Wood (4924), Lawn Stephen D., Susan Cleary, Susan Cleary (158497), Stephen D. Lawn, Harrison, Thomas S, Cleary, S, Wood Robin, Harrison, TS, Thomas S. Harrison, Cleary Susan, Lawn, SD, Graeme Meintjes, Meintjes, G, Jarvis, Joseph N, Wood, Robin   +32 more
core   +1 more source

Additivity interactions between fluconazole and citrus essential oils to Aspergillus fumigatus

Journal of Pre-Clinical and Clinical Research, 2021
Introduction Aspergillus fumigatus is the most common pathogen causing allergic bronchopulmonary mycosis. The pathogenic capacity of Aspergillus fumigatus is related to its thermal tolerance and the small size of the ...
Paula Wróblewska-Łuczka, Jarogniew Łuszczki   +1 more
doaj   +1 more source