Results 51 to 60 of about 605,588 (181)

Tolerance analysis approach based on the classification of uncertainty (aleatory / epistemic) [PDF]

, 2012
Uncertainty is ubiquitous in tolerance analysis problem. This paper deals with tolerance analysis formulation, more particularly, with the uncertainty which is necessary to take into account into the foundation of this formulation.
Qureshi, A.J., LEMAIRE, Maurice, Etienne, A., DANTAN, Jean-Yves, Gayton, Nicolas, QURESHI, Ahmed Jawad, GAYTON, N., Lemaire, M., ETIENNE, Alain, Dantan, J.Y.   +9 more
core   +1 more source

Antifungal Susceptibility Testing of Five Antifungal Agents against Clinically Isolated Dermatophytes Species from a Tertiary Care Hospital in Northern India [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Dermatophytosis form approximately 15-75% of all the mycological infections. Dermatophytes are closely related keratinolytic fungi with ability to degrade keratin and invade the skin, hair and nails causing dermatophytosis.
Sachin Sharma, Megha Maheshwari, Rameshwari Thakur, Sumesh Prasad Sah, Sapna Chauhan   +4 more
doaj   +1 more source

Recent Increase in the Prevalence of Fluconazole-Non-susceptible Candida tropicalis Blood Isolates in Turkey: Clinical Implication of Azole-Non-susceptible and Fluconazole Tolerant Phenotypes and Genotyping [PDF]

Frontiers in Microbiology, 2020
Candida tropicalis is the fourth leading cause of candidemia in Turkey. Although C. tropicalis isolates from 1997 to 2017 were characterized as fully susceptible to antifungals, the increasing global prevalence of azole-non-susceptible (ANS) C. tropicalis and the association between high fluconazole tolerance (HFT) and fluconazole therapeutic failure ...
Amir Arastehfar, Süleyha Hilmioğlu-Polat, Farnaz Daneshnia, Ahmed Hafez, Mohammadreza Salehi, Furkan Polat, Melike Yaşar, Nazlı Arslan, Tuğrul Hoşbul, Nevzat Ünal, Nevzat Ünal, Dilek Yeşim Metin, Şaban Gürcan, Asuman Birinci, Ayşe Nedret Koç, Weihua Pan, Macit Ilkit, David S. Perlin, Cornelia Lass-Flörl   +18 more
openaire   +7 more sources

Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal. [PDF]

, 2013
Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice.
A. Loyse, Dromer, F, Day, J, Lortholary, O, O. Lortholary, Harrison, TS, F. Dromer, Day, Jeremy, T. S. Harrison, J. Day, Loyse, A   +10 more
core   +1 more source

Species Distribution and in Vitro Antifungal Susceptibility of Oral Yeast Isolates from Tanzanian HIV-Infected Patients With Primary and Recurrent Oropharyngeal Candidiasis. [PDF]

, 2008
\ud In Tanzania, little is known on the species distribution and antifungal susceptibility profiles of yeast isolates from HIV-infected patients with primary and recurrent oropharyngeal candidiasis.
Rijs Antonius JMM, Mugusi Ferdinand, Simon Elison NM, van der Ven, A.J., Rijs, A.J.M.M, Verweij, P.E., Verweij, P.E, Simon, Elison N M, Matee, Mecky I N, Palenstein Helderman, W.H. van, Moshi, M.J, Van Palenstein Helderman, W.H, Moshi, Mainen J, Rijs, Antonius J M M, Hamza, O.J.M., Wim Helderman, Frans HM Mikx, Simon, E.N.M., Verweij, Paul E, Ferdinand Mugusi, Mugusi, Ferdinand, Hamza, Omar J M, van der Ven André JAM, Antonius JMM Rijs, Mikx, F.H.M., Rijs, A.J.M.M., Elison NM Simon, Ven, A.J.A.M. van der, Mikx Frans HM, Matee Mecky IN, Matee, M.I.N, Simon, E.N., Verweij Paul E, Paul E Verweij, Helderman, W.H.P., Moshi, M.J., Moshi Mainen J, Simon, E.N.M, Helderman, Wim H van Palenstein, André JAM van der Ven, Mecky IN Matee, Mikx, Frans H M, Omar JM Hamza, Mugusi, F., van der Ven, André J A M, Mainen J Moshi, Matee, M.I.N., Mikx, F.H.M, Van der Ven, A.J.A.M, Hamza, O.J.M, Hamza Omar JM, Helderman Wim   +51 more
core   +2 more sources

Machine Learning Approach for Candida albicans Fluconazole Resistance Detection Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

Frontiers in Microbiology, 2020
Candida albicans causes life-threatening systemic infections in immunosuppressed patients. These infections are commonly treated with fluconazole, an antifungal agent targeting the ergosterol biosynthesis pathway.
Margot Delavy, Lorenzo Cerutti, Antony Croxatto, Guy Prod’hom, Dominique Sanglard, Gilbert Greub, Alix T. Coste   +6 more
doaj   +1 more source

Poor long-term outcomes for cryptococcal meningitis in rural South Africa. [PDF]

, 2011
OBJECTIVES: To explore linkage to and retention in HIV care after an episode of cryptococcal meningitis (CM) in rural South Africa. Design. A retrospective case series of adult individuals (> or = 16 years old) with laboratory-confirmed CM from January -
Newell, Marie-Louise, Heller, T, Mutevedzi, PC, Heller, Tom, Lessells, Richard J, Newell, ML, Lessells, RJ, Mutevedzi, Portia C   +7 more
core   +1 more source

Comparative fitness trade-offs associated with azole resistance in Candida auris clinical isolates

Heliyon
Multidrug-resistant yeast Candida auris is a serious threat to public health with documented survival in various hospital niches. The dynamics of this survival benefit and its trade off with drug resistance are still unknown for this pathogen.
Sourav Das, Shreya Singh, Yamini Tawde, Tushar K. Dutta, Shivaprakash M. Rudramurthy, Harsimran Kaur, Tushar Shaw, Anup Ghosh   +7 more
doaj   +1 more source

Phytochemistry, Chemotypic Diversity and Antimicrobial Potential of Essential Oils From Native Aromatic Plants of the Americas: A Systematic Review

Flavour and Fragrance Journal, EarlyView.
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez, Mozaniel Santana de Oliveira, João Paulo Viana Leite   +2 more
wiley   +1 more source

Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans [PDF]

Molecular Microbiology, 2012
SummaryThis study shows the importance of PDK1, TOR and PKC signalling pathways to the basal tolerance of Cryptococcus neoformans towards fluconazole, the widely used drug for treatment of cryptococcosis. Mutations in genes integral to these pathway resulted in hypersensitivity to the drug. Upon fluconazole treatment, Mpk1, the downstream target of PKC
Hyeseung, Lee, Ami, Khanal Lamichhane, H Martin, Garraffo, Kyung J, Kwon-Chung, Yun C, Chang   +4 more
openaire   +2 more sources